The Dr. Eileen Berman and Stanley Berman Foundation Chair in Biomedical Research, Professor, Program in Molecular Medicine,
Co-Director, UMass Chan Diabetes Center of Excellence

Reconstructing & studying human Type 1 diabetes in our humanized mice as preclinical models using cells and tissues derived from T1D patients 

Testing encapsulation devices and genetically modified stem cell-derived insulin-producing beta cells to protect them from autoimmune attack

The William and Doris Krupp Professor of Medicine, Co-Director, UMass Chan Diabetes Center of Excellence, Director, JDRF Center of Excellence in New England

Exploring beta cell biology and anti-beta cell immune responses underlying Type 1 diabetes

Developing innovative techniques to sort human pancreatic islet cell subsets from donors with both Type 1 and Type 2 diabetes to determine the transcriptome from those purified cells

Associate Professor, Program in Molecular Medicine, Co-Director, UMass Humanized Mouse Core, Investigator, JDRF Center of Excellence in New England

Developing unique humanized mouse models to observe and identify immune mechanisms that regulate Type 1 diabetes development

Investigating interactions between human pancreatic beta cells and immune cells from individuals with Type 1 diabetes in vivo to understand the etiology and pathogenesis of autoimmune T1D

Assistant Professor, Program in Molecular Medicine, UMass Chan Diabetes Center of Excellence, JDRF Center of Excellence in New England

Investigating the influence of molecular metabolism on cell function and fate in pancreatic beta cells and local immune cells in health, obesity and diabetes. We've identified metabolic pathways which protect against inflammation associated with metabolic disease. Now we're looking at how these pathways shape the metabolic milieu of pancreatic islets and local immune cell activities using metabolomics, proteomics and transcriptomics.

Endowed Chair in Diabetes Research, Director, Clinical Translational Research Pathway, T.H. Chan School of Medicine, Professor, Program in Molecular Medicine

Professor, Program in Molecular Medicine, The Isadore and Fannie Foxman Chair of Medical Research

Investigating molecular mechanisms whereby insulin signaling regulates energy homeostasis

Gene editing & deletion to enhance insulin signaling/energy expenditure in Type 2 diabetes & obesity

Techniques include RNAi screens, digital imaging, TIRF microscopy, gene knockouts and analysis of human adipose tissues

Chair, Program in Molecular Medicine, H. Arthur Smith Chair in Biomedical Research, Howard Hughes Medical Institute Investigator

Investigating molecular mechanisms by which inflammation contributes to Type 2 diabetes, cancer & stroke

Our studies of stress signaling pathways have led to the discovery of new genes that contribute to the development of Type 2 diabetes and other metabolic diseases

Professor, Program in Molecular Medicine

Investigating insulin resistance development in obesity and lipodystrophy

Identifying therapeutic strategies to improve how the body processes blood glucose

Exploring biochemical mechanisms controlling cell growth and metabolism and their significance to the pathogenesis of Type 2 diabetes

The George F. and Sybil H. Fuller Term Chair in Diabetes, Associate Professor, Department of Medicine, Investigator, JDRF Center of Excellence in New England

Professor of Molecular Medicine, Professor, Division of Endocrinology, Metabolism and Diabetes, Director of National Mouse Metabolic Phenotyping Center

Associate Professor, Program in Molecular Medicine, Investigator, JDRF Center of Excellence in New England

Johnnie Ray Cox Term Chair in Biomedical Research, Professor and Vice Chair, Department of Surgery

Investigating new hematopoietic stem cell–based therapeutic approaches to treat people with Type 2 diabetes and other common diseases

Determining the effects of Type 2 diabetes on wound healing and identifying the molecular & cellular mechanisms that could lead to potential therapies

Chair and Professor, Department of Obstetrics and Gynecology, Professor of Pediatrics, Psychiatry and Population & Quantitative Health Sciences, Founding Director of the Ob/Gyn Research Division

Professor of Medicine, Division of Infectious Diseases and Immunology, Investigator, JDRF Center of Excellence in New England