World-Class Diabetes Research
Research to Prevent and Cure Diabetes at UMass Chan Medical School
Under the co-direction of Dale L. Greiner, PhD, and David M. Harlan, MD, the goal of the Diabetes Center of Excellence (DCOE) at UMass Chan Medical School is to prevent and cure diabetes. DCOE research faculty are gaining new knowledge of the disease by studying human tissues & human cells inside of our novel biological models that mimic the human immune system. Understanding what causes diabetes will allow us to develop effective therapies and ultimately find the cure.
Research Strategies
Meet the UMass Diabetes Center of Excellence Scientists
Diabetes Research Laboratories
DCOE News
Total: displaying 5 out of 126 results-
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Guertin Lab Publication in Nature Discovers New Information About Brown Fat Metabolism
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Studying Blood Glucose Management During Pregnancy to Improve the Health of Mothers and Children
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Study to Boost Energy Production in Fat Cells Could Lead to Weight Maintenance Therapies
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Investigating the Effects of High Cholesterol on Artery Development in the Messina Lab
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Six Sigma Project Reduced Prescription Wait Times and Increased Efficiency in the Endocrinology & Diabetes Clinics
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Understanding Liver Disease and Its Connection to Type 2 Diabetes
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Developing Improved Models for Cutting-Edge Immune Cell Studies to Accelerate Disease Treatments in the Brehm & Greiner Laboratories
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UMass Memorial Diabetic Health Outreach Clinic for Worcester's Underserved Community
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Adipose (Fat) Tissue Plays an Important Role in the Aging Process
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Michael Brehm, PhD, Promoted to Associate Director
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Czech Lab PhD Student Najihah Aziz Wins Three Minute Thesis Competition
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Certified Child Life Specialists in Pediatric Diabetes Care
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Berkman Diabetes Clinical Innovation Grant to Develop Liver Screening in the Adult Diabetes Clinic
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Free Diabetic Health Outreach Clinic for Worcester's Underserved Community
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Generation and Molecular Characterization of Human Pluripotent Stem Cell-Derived Pharyngeal Endoderm
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Surgeon-Scientist Tammy Nguyen Found a Distinct Class of Stem Cells Develop from Yellow Bone Marrow in Humans
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Tree Connected to "Father of Medicine" Planted Between the UMass Chan Diabetes Clinic and Research Laboratories
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John Haley Awarded Emerging Scientist in Metabolism Prize
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Shrewsbury High School Teacher Completes American Association of Immunologists Research Program at UMass Diabetes Center of Excellence
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Young Adult Clinic Pilot Program to Improve Diabetes Care at UMass Memorial
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Researcher Spotlight: Sambra Redick, PhD - Creating Stem Cell-Derived Pancreatic Islets
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New “Humanized” Mouse Model Supports Human Immune System Development and the Study of Human-Specific Innate Immunity in the Brehm & Greiner Labs
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UMass Chan Medical School Student Conducting Pilot Study to Analyze Skin Reactions to CGM at UMass Memorial Diabetes Center of Excellence
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Testing Efficacy and Impact of an AI Diabetic Retinopathy Screening Program in Primary Care Clinics
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$500K from the Arthur M. and Martha R. Pappas Foundation to Advance UMass Chan Diabetes Research Capabilities
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Secreted Protein in Brown Fat Shown to Control Thermogenesis and Blood Glucose
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Wang Lab Study Finds Early Islet Transcriptional Signature is Associated with Local Inflammation in Type 1 Diabetes
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UMass Memorial Diabetic Health Clinic for Worcester's Underserved
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Joseph Nozzolillo Memorial Foundation Surpassed $111,000 in Fundraising for UMass Chan Diabetes Center of Excellence Research
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Diabetes Center of Excellence Immunologist Sally Kent Investigating Autoreactive T Cell Function in Vitiligo
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The Czech Lab Reviews the Adipocyte Supersystem of Insulin and cAMP Signaling in Trends in Cell Biology
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The Kent Lab is Investigating the Role of Extracellular Vesicles in the Development of Type 1 Diabetes
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Endocrinologist Mark O'Connor Awarded Academic Collaboration Prize to Study the Use of Smart Watch Technology to Prevent Dangerous Hypoglycemia
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Investigating CAR T Cell Therapy Targeting Type 1 Diabetes Specific Cells in the Kent and Brehm Labs
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Enhanced Development of Functional Human Natural Killer Cells for Pre-Clinical Study in the Greiner and Brehm Labs
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Tammy Nguyen Receives NIDDK K08 Career Development Award to Investigate and Improve Non-Healing Wounds in People with Type 2 Diabetes
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Investigating a Potential Path to Medication for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in the Czech Lab
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Studying the Benefits of Continuous Glucose Monitors to Reduce Hospitalizations and Diabetic Complications
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Jason Kim's Lab is Hosting Visiting Researchers from South Korea to Conduct Type 2 Diabetes Research
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Diabetes Virtual Camp for Future Scientists and Physicians Created by the Family of UMass Diabetes Researcher Jason Kim
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UMass Diabetes Center of Excellence Co-Director David Harlan Appointed Director of the JDRF Research Center in New England
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Vascular Surgeon-Scientist Tammy Nguyen Received the Wylie Scholar Award For Diabetic Wound Healing Research
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Diabetes Coaching Program is Helping Struggling Patients Improve Dangerously High Blood Sugars
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Endocrinologist Mark O'Connor Identifying Genes Linked to the Risk of Developing Type 2 Diabetes
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Genetically Modifying Adipocytes to Increase Fat Burning and Improve Metabolic Function as a Potential Therapy for Type 2 Diabetes
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Guertin Lab Reviews the Multi-omics Era of Adipocyte Insulin Signaling and Metabolism Research in Trends in Biochemical Sciences
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Two UMass Chan Medical Students Created an Elective Course Teaching In-Depth Diabetes Management and Care
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Affordable Insulin Now Act Includes a Monthly Out-Of-Pocket Patient Maximum of $35 for Insulin Prescriptions
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The Diabetes Center of Excellence and Worcester Polytechnic Institute Awarded a Grant to Develop Type 1 Diabetes Research Tools
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Gene Engineering of Fat Cells as a Potential Therapy for Type 2 Diabetes
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Identifying Genes and Signaling Pathways to Develop Thymus Cells to Explore the Root Cause of Type 1 Diabetes in the Maehr Lab
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The Latest Blood Glucose Management Tools and Products
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Gene Analysis Research Uncovered a Physiological Brake Protecting Thermogenesis in Fat Tissue
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Modeling and Studying the Autoimmune Processes of Human Type 1 Diabetes Using Human Cells and Tissues
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Diabetes Nurse Practitioner Nancy Sidhom Describes the Benefits of Continuous Glucose Monitors
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Identifying Therapeutic Targets Using RNAi Technology to Treat Liver Disease in the Czech Lab
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Type 2 Diabetes Researcher Spotlight: Adilson Guilherme, PhD
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The Wang Lab Sheds New Light on the Relationship Between Viral Infections and Type 1 Diabetes
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Greiner Lab Helping to Improve a Macroencapsulation Device to Advance the Development of Beta Cell Replacement Technology
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Bioinformatician Mason Tarpley Named UMass Chan Diabetes Center of Excellence Cammett Scholar in Type 1 Diabetes Research
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Mello Scholar Awards Recognize Molecular Research, including Type 2 Diabetes Studies at UMass Chan Medical School
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Type 2 Diabetes Research in the Guertin Lab Tracked and Discovered New Functions of Glucose in Brown Fat
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Researcher Spotlight: Carey Zammitti
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Investigating Leptin Regulation of the Human Diabetic Immune System in Nonhealing Diabetic Foot Ulcers
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The COVID-19 Pandemic and Pediatric Type 1 Diabetes
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FDA Approves Interchangeable Biosimilar Insulin to Potentially Reduce Cost for People to Treat Diabetes
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Means, Motive, and Opportunity: Investigating the Role of Immune Cells in the Development of Type 1 Diabetes
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UMass Diabetes Nurse Practitioner Sean Collins Appointed Commander of the Air Force Medical Readiness Agency
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Roger Davis Elected to The American Academy of Arts & Sciences
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UMass Diabetes Center of Excellence Researchers Recognized in Cell Metabolism's 100 Years of Insulin Issue
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Newly Published Clinical Study Evaluates a Remote Glucose Monitoring Program to Help People With Poorly Controlled Type 2 Diabetes at UMass Memorial
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Researcher Spotlight: Sushobhana Bandyopadhyay, PhD
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A Collaboration to Genetically Engineer Human Insulin-Producing Beta Cells as a Potential Therapeutic Cure for Type 1 Diabetes
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Dr. David Harlan Celebrates 100 Years Since the Initial Purification & Use of Insulin in Diabetes Therapy with "The Noble and Often Nobel Role of Insulin-Related Research"
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Vascular and Endovascular Surgery Society Award to Investigate Diabetic Wound Healing in the Nguyen Lab
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Diabetes Virtual Camp for Future Scientists and Physicians Created by the Family of UMass Diabetes Researcher Jason Kim
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Davis Lab Investigating a Potential Hormone Therapy for Type 2 Diabetes
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Protein Commonly Screened For During Pregnancy is Linked to Gestational Diabetes
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Re-engineering “Bad Fat” into “Good Fat” as a Therapeutic Approach to Type 2 Diabetes in the Czech & Corvera Labs
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Studying Fat Cell Function in the Guertin Lab in an Effort to Develop & Test Therapies for Type 2 Diabetes
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The Corvera Lab is Examining How Different Body Fat Plays a Role in Type 2 Diabetes
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Mello Scholars Recognized for Molecular Research at UMass Chan Medical School in Pursuit of the Advancement of Human Health
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Corvera Lab Leading a Clinical Study to Investigate the Relationship Between Fat, Diabetes and Obesity
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The Kim Lab Participated in Newly Published Collaborative Type 2 Diabetes Research That Identified a Potential Oral Treatment
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Research Project by Medical Students Looks at Improving Prediabetes and Diabetes in Primary Health Care
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Modeling Type 1 Diabetes Using Human Stem Cells in the Brehm and Greiner Labs
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Physician-Scientist Jennifer Wang Uses Stem-Cell Derived Beta Cells to Study the Effects of Viral Infections on Type 1 Diabetes Development
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Virtual Telehealth Could Become the New Normal in Diabetes Care
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Smaller Pancreas Size in People with Type 1 Diabetes Suggests It's More than Just a Beta Cell Problem
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Type 2 Diabetes Research in the Czech Lab Investigating Beige Fat to Potentially Increase Metabolism
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Continuous Glucose Monitors Now Permitted at UMass Memorial to Monitor Diabetes Patients and Protect Hospital Workers During the COVID-19 Pandemic
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Alan Derr Named Cammett Scholar in Type 1 Diabetes Research at UMass Chan Medical School
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Guertin Lab Published New Data About mTORC2 Signaling in Brown Adipocytes
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Program Developed to Help At-Risk Type 2 Diabetes Patients Receive Necessary Care
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Glass Family Fellowship in Diabetes Research Established at the UMass Chan Medical School Diabetes Center of Excellence
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Davis Lab Sheds Light on Complications From High Blood Glucose and Excess Body Fat Which Lead to Type 2 Diabetes
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Guertin Lab mTORC2 Signaling Study Published in Nature Communications
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Developing a Thymus in the Maehr Lab to Improve Type 1 Diabetes Research
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The Harlan and Greiner Labs Developed a Method to Study Human Cells and Tissue That Improves Type 1 Diabetes Research
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Using RNA Interference to Study Behaviors and Function Cells Within Adipose Fat Tissue and the Effect on Blood Glucose Metabolism
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David Harlan Interviews Nobel Laureate Wally Gilbert About Pioneering Work in DNA Sequencing That Led to the Creation of the First Genetically Engineered Human Insulin
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Sally Kent Named Fuller Foundation Term Chair in Diabetes at UMass Chan
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Guertin Lab review on the metabolism of fat cells in type 2 diabetes published in Current Diabetes Reports
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Mapping Your Plan to Control Blood Glucose with Diabetes Education
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Carl H. June, MD, pioneer of CAR T Cell Immunotherapy
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The Corvera Lab Discovered New Fat Cells with Specialized Functions in Human Metabolism
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Testing a Lockheed Martin Developed Pancreatic Islet Encapsulation Device
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Herman G. Berkman Diabetes Clinical Innovation Grant Awarded to Improve Inpatient Diabetes Care at UMass Memorial Hospitals
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The Harlan and Kent Labs Resolved a 30 Year Debate by Locating Beta Cells in People with Type 1 Diabetes That Express Important Immune Pathway Gene Products
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Corvera Lab is Creating "Good Fat" as a Potential Therapy for Type 2 Diabetes
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Newly Published Research in the Brehm and Davis Labs Uncovered New Memory T Cells Data
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UMass Diabetes Center of Excellence Receives a $10.5K Gift From a Grateful Family
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Michael Czech and Silvia Corvera receive $2.5 million grant to advance potential therapy for type 2 diabetes
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Unexpected cell population slows down fat cells
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Infectious Disease Expert Jennifer Wang Receives Funding to Identify Immune Responses and Investigate How Viruses Trigger Type 1 Diabetes
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Why Language is Important in Diabetes Management
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Care Team Spotlight: Cheryl Barry, RN, MS, CDCES
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The Maehr Lab's Thymus Development Study Featured as the Cover Story in Immunity
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The Role of a Nurse Practitioner in Diabetes Care
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Roger Davis Elected into the National Academy of Sciences
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Nancy Morris Receives Excellence in Nursing Education Award from American Nursing Association Massachusetts
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Sally Kent receives Pioneer Award from the Network for Pancreatic Organ Donors with Diabetes (nPod)
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The Corvera Lab Sheds Light on Beige Fat as a Potential Therapy for Type 2 Diabetes
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The Kent and Harlan Labs Isolated Immune Cells from Islets of Donors with Type 1 Diabetes
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UMass Chan Medical School hosts American Diabetes Association Step Out Walk to Stop Diabetes
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Patient Wall of Honor
After 10 years of taking oral medication for his type 2 diabetes, Dan's weight and A1c were both on the rise. He was prescribed insulin by his primary care physician in Ohio, where he resides, but did not feel he was receiving the support necessary to improve his health. Dan's diabetes control greatly improved after he reconnected with his high school friend, Dr. David Harlan. Dan's Story
Jason Winters has been living with type 1 diabetes since he was 21 years old. After 10 years of uncontrolled blood sugars, his primary care physician referred him to the UMass Memorial Diabetes Center of Excellence. He arrived with a dangerously high A1c of 12.3% and today it's below 7%. His journey wasn't easy, but working with his care team and using the latest technology, Jason's diabetes is finally under control and his health is improving.
Meet Jason