Publications

Cryo-EM structure of the human cardiac myosin filament Dutta, Debabrata; Nguyen, Vu; Campbell, Kenneth S; Padrón, Raúl; Craig, Roger Pumping of the heart is powered by filaments of the motor protein myosin that pull on actin filaments to generate cardiac contraction. In addition to myosin, the filaments contain cardiac myosin-binding protein C (cMyBP-C), which modulates contractility in response to physiological stimuli, and t...

First pass effect as an independent predictor of functional outcomes in medium vessel occlusions: An analysis of an international multicenter study Radu, Răzvan Alexandru; Costalat, Vincent; Fahed, Robert; Ghozy, Sherief; Siegler, James E; Shaikh, Hamza; Khalife, Jane; Abdalkader, Mohamad; Klein, Piers; Nguyen, Thanh N; Heit, Jeremy J; Sweid, Ahmad; El Naamani, Kareem; Regenhardt, Robert W; Diestro, Jose Danilo Bengzon; Cancel...

Stent-assisted Woven EndoBridge device for the treatment of intracranial aneurysms: an international multicenter study Diestro, Jose Danilo Bengzon; Dibas, Mahmoud; Adeeb, Nimer; Regenhardt, Robert W; Vranic, Justin E; Guenego, Adrien; Lay, Sovann V; Renieri, Leonardo; Balushi, Ali Al; Shotar, Eimad; Premat, Kévin; Namaani, Kareem El; Saliou, Guillaume; Möhlenbruch, Markus A; Lylyk, Ivan; Foreman, Paul M; Vachhani, Jay A; Župa...

Leveraging Differences in AI and Human "Vision" to Improve Breast Cancer Detection Mehta, Tejas S Screening mammography is the single most effective test to reduce breast cancer mortality. Despite improvements in mammography technology, including digital breast tomosynthesis, it remains an imperfect test, with one in eight cancers missed at time of interpretation. Supplemental imaging with US, contrast-enhanced MRI, or contras...

First United States multicenter experience with the new-generation FRED X surface-modified flow diversion stent: feasibility, safety, and short-term efficacy Abbas, Rawad; Lan, Matthews; Naamani, Kareem El; Atallah, Elias; Salem, Mohamed; Burkhardt, Jan-Karl; Kühn, Anna Luisa; Puri, Ajit; Monteiro, Andre; Levy, Elad I; Herial, Nabeel A; Gooch, M Reid; Jabbour, Jeffrey; Rosenwasser, Robert; Tjoumakaris, Stavropoula I Objective:...

Surface modification of neurovascular stents: from bench to patient Zoppo, Christopher T; Mocco, J; Manning, Nathan W; Bogdanov, Alexei A. Jr.; Gounis, Matthew J Flow-diverting stents (FDs) for the treatment of cerebrovascular aneurysms are revolutionary. However, these devices require systemic dual antiplatelet therapy (DAPT) to reduce thromboembolic complications. Given the risk of ischemic complications as well as morbidity...

Phosphaturic mesenchymal tumor: two cases highlighting differences in clinical and radiologic presentation Gu, Joey; Ge, Connie; Joshi, Ganesh; Most, Mathew; Tai, Ryan Phosphaturic mesenchymal tumors are rare, usually benign neoplasms that occur in the soft tissue or bone and are the cause of nearly all cases of tumor-induced osteomalacia. Tumor-induced osteomalacia due to phosphaturic mesenchymal tumor is a challenging diagno...

Dissecting aneurysm of the Posterior Cerebral Artery Kuhn, Anna Luisa; Puri, Ajit S; Singh, Jasmeet Posterior circulation aneurysms are more likely to rupture than those in the anterior circulation but also pose more of a challenge for endovascular treatment or neurosurgical clipping. Aneurysms arising from the posterior cerebral artery are rare; dissecting aneurysms are even rarer. Dissecting posterior cerebral artery aneurys...

Awake intracerebroventricular delivery and safety assessment of oligonucleotides in a large animal model Benatti, Hector Ribeiro; Prestigiacomo, Rachel D; Taghian, Toloo; Miller, Rachael; King, Robert; Gounis, Matthew J; Celik, Ugur; Bertrand, Stephanie; Tuominen, Susan; Bierfeldt, Lindsey; Parsley, Elizabeth; Gallagher, Jillian; Hall, Erin F; McElroy, Abigail W; Sena-Esteves, Miguel; Khvorova, Anastasia; Aronin, Neil; Gray-Ed...

Transvenous Embolization of Dural Arteriovenous Fistulas Through the Galenic (Deep Venous) System: Multicenter Case Series and Meta-Analysis Srinivasan, Visish M; Karahalios, Katherine; Colasurdo, Marco; Rhodenheiser, Emmajane; Scherschinski, Lea; Lazaro, Tyler T; Cortez, Gustavo; Gross, Bradley A; Kuhn, Anna Luisa; Puri, Ajit S; Winkler, Ethan A; Catapano, Joshua S; Akamatsu, Yosuke; Thomas, Ajith; Hanel, Ricardo A; Wakhloo, ...