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updated.gif 07/04/2024

The COMP005 study is looking into a new investigational treatment approach for people with treatment-resistant depression (TRD).  TRD is depression that has failed to respond to treatment with 2, 3 or 4 pharmacological medications.

  • You may be able to join this study if you:
  • Are 18 years of age or older
  • Have major depression and have not responded to antidepressant

The study, which will last up to 62 weeks, will compare the effectiveness of an investigational medicine versus placebo, a substance that has no therapeutic effect, given with psychological support.  If you are interested in learning more about the COMP005 study, you can find out more by visiting

You can also call us at your local study center to find out more.
Please note that expressing an interest does not oblige you in any way to take part in the study. So please, do get in touch if you want to find out more. Reimbursement may be available for time and travel.

Email CPRT team at or call: 508-856-1882

 IRB ID STUDY00000671-AJRothschild


Are you suffering from depression?
Is your current antidepressant not working and you are planning to take an additional medication or non-medication treatment?

Learn more about the observational VENTURA‑RWE study, which may be an option for you.

Reimbursement for travel will be available for qualified participants.

Email CPRT team at or call: 508-856-1882

WCG STUDYID1364569 - AJRothschild


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