Depression

05/03/2025

The COMP005 study is looking into a new investigational treatment approach for people with treatment-resistant depression (TRD).  TRD is depression that has failed to respond to treatment with 2, 3 or 4 pharmacological medications.

• You may be able to join this study if you:
• Are 18 years of age or older
• Have major depression and have not responded to antidepressant

The study, which will last up to 62 weeks, will compare the effectiveness of an investigational medicine versus placebo, a substance that has no therapeutic effect, given with psychological support.  If you are interested in learning more about the COMP005 study, you can find out more by visiting www.compasspathfinderstudies.com.

You can also call us at your local study center to find out more.
Please note that expressing an interest does not oblige you in any way to take part in the study. So please, do get in touch if you want to find out more. Reimbursement may be available for time and travel.

Email CPRT team at CPRTResearchOffice@umassmed.edu or call: 508-856-1882

 IRB ID STUDY00000671-AJRothschild

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