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MDCCC Physicians - Kristina M. Deligiannidis, M.D.


Kristina M. Deligiannidis, M.D.
Assistant Professor of Psychiatry and Obstetrics & Gynecology, UMass Chan Medical School
Medical Director, Depression Specialty Clinic at UMassMemorial Medical Center
Psychiatrist, Women's Mental Health Specialty Clinic at UMassMemorial Medical Center

Dr. Deligiannidis completed her undergraduate degrees and a Research Program in Neuroscience and Behavior at the University of Massachusetts at Amherst. As a recipient of NIH pre-doctoral Intramural Research Training Awards, she trained in molecular neuroendocrinology research at the NIH/National Institutes of Child Health and Human Development (NIH/NICHD). Her research was in the neural regulation of melatonin in the pineal gland by serotonin N-acetyltransferase.

Dr. Deligiannidis completed additional research training at the National Institute of Mental Health (NIMH) and NICHD during medical school and residency. She received her medical degree from the UMass Chan Medical School and completed her psychiatry residency and chief residency in psychopharmacology research at UMass Chan Medical School (UMass Chan)/UMass Memorial Health Care (UMMHC). Dr. Deligiannidis joined faculty at UMass Chan in October 2009 as an Assistant Professor of Psychiatry.

Dr. Deligiannidis is the Director of the Depression Specialty Clinic, a faculty-supervised resident and fellow clinic that specializes in the evaluation of adult patients suffering from depression. Dr. Deligiannidis additionally evaluates and treats women in the Women’s Mental Health Specialty Clinic at UMMHC. She provides initial evaluations and short-term treatment of women suffering from depression and anxiety during pregnancy or the post-partum period as well as preconception consultations regarding the use of medications during pregnancy and lactation.

Dr. Deligiannidis evaluates participants enrolled in depression research including research with investigational medications and neuromodulation in the Center for Psychopharmacologic Research & Treatment and conducts translational research into the causes of depression in women which occurs in pregnancy and the postpartum period. Her research involves the use of neuroimaging and measurement of endocrine biomarkers in depression.

Research Could Pinpoint Postpartum Depression Risks, By Sera Congi, WBZ-TV
Study uses brain imaging to understand postpartum depression, UMassMed

Dr. Deligiannidis' research efforts have been nationally recognized. She is the recipient of: a 2011 UMass Chan Medical School Center for Clinical & Translational Science (CTSA)-funded Pilot Project Program Grant, a 2011 Society for Biological Psychiatry Travel Scholarship Award, a 2010 Worcester Foundation for Biomedical Research Grant; 2010 Career Development Institute (CDI) for Psychiatry Award (NIMH R13MH069748 University of Pittsburgh/Stanford University), a 2009 NIMH/NCDEU New Investigator Award, APA/APIRE Junior Investigator Awards (2008, 2009) and American Society of Clinical Psychopharmacology/NIMH Clinical Trials in Psychopharmacology Awards (2007, 2008).

Dr. Deligiannidis is an appointed Young Investigator Member of the International Society of Psychoneuroendocrinology (ISPNE) and a member of the Society of Behavioral Neuroendocrinology (SBE), the Organization for Human Brain Mapping (OHBM), the American Society of Clinical Psychopharmacology (ASCP), the Marcé Society, the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG), the Association of Women Psychiatrists, the American Psychiatric Association (APA) and the Massachusetts Psychiatric Society (MPS).

Representative Publications:
  1. Deligiannidis KM, Girgis RR, Lau A, Balon R, Zisook S. (2012) A psychiatry resident/fellow initiated and designed multi-modal psychopharmacology curriculum for major depression. Academic Psychiatry, in press.
  2. Deligiannidis KM. The use of antidepressants in pregnancy and lactation. In AJ Rothschild (Ed.), The Evidence-Based Guide to Antidepressants. Arlington, VA: American Psychiatric Publishing, Inc. (APPI), 2012.
  3. Moore Simas T, Byatt N, Deligiannidis KM. (2011) Clinical Roundup: How do you treat premenstrual syndrome in your practice? Alternative and Complementary Therapies 17(4):237.
  4. Prabhakar D, Balon R, Deligiannidis, KM, Zisook S. (2011) The American Society for Clinical Psychopharmacology’s Modules in Depression and Bipolar Disorder: Answering the Call for a Model Curriculum, Original Contribution, Revista de Trastornos del Ánimo 7 (1): 8-13.
  5. Deligiannidis KM. (2011) Depression in women during childbearing years: causes, symptoms, challenges and treatment. Psychiatry Issue Briefs: Vol. 8: Iss. 1, Article 1. Available at
  6. Deligiannidis KM. (2010) Therapeutic drug monitoring in pregnant and postpartum women: Recommendations for SSRIs, lamotrigine and lithium. Journal of Clinical Psychiatry 71(5):649-650.
  7. Deligiannidis KM, Freeman MP. (2010) Complementary and alternative medicine for the treatment of depressive disorders in women. Psychiatric Clinics of North America 33(2):441-463.
  8. Patel JK, Deligiannidis KM: The Use of Antipsychotics in Schizophrenia and Schizoaffective Disorder. In AJ Rothschild (Ed.), The Evidence-Based Guide to Antipsychotics. Arlington, VA: American Psychiatric Publishing, Inc. (APPI), 2010.
  9. Deligiannidis KM, Rothschild AJ: The Use of Antipsychotics in Mood and Anxiety Disorders. In AJ Rothschild (Ed.), The Evidence-Based Guide to Antipsychotics. Arlington, VA: American Psychiatric Publishing, Inc. (APPI), 2010.
  10. Marsh WK, Deligiannidis KM. (2010) Sex-related differences in antidepressant response: When to adjust treatment. Current Psychiatry 9(5):25-30.
  11. Falcon J, Galarneau KM, Weller JL, Ron B, Chen G, Coon SL, Klein DC. (2001) Regulation of Arylalkylamine N-Acetyltransferase-2 in the Fish Pineal Organ: Evidence for a Role of Proteasomal Proteolysis. Endocrinology 142:1804-1813.