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RNA Therapeutics Institute Faculty

  • Neil Aronin

    Neil Aronin, MD

    Professor, Department of Medicine

    Focus:
    Pathogenesis of neurodegenerative diseases, especially Parkinson's disease and Huntington's disease.

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  • Nikolaus Grigorieff

    Nikolaus Grigorieff

    Professor

    Focus:
    High-resolution electron cryo-microscopy of macromolecular machines to understand their molecular mechanisms and the cellular processes they are involved in.

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  • David Grunwald

    David Grunwald, PhD

    Associate Professor

    Focus:
    The interface between microscopy development and (nuclear) cell biology, with a strong focus on the travels of mRNA and nucleocytoplasmic transport.

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  • Anastasia Khvorova

    Anastasia Khvorova, PhD

    Professor

    Focus:
    Development of novel oligonucleotide-based therapeutics, drug development. Mechanism of small RNA trafficing, RNA medicinal chemistry and delivery.

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  • Andrei Korostelev

    Andrei Korostelev, PhD

    Associate Professor

    Focus:
    Structure and function of ribosome.

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  • Craig Mello

    Craig Mello, PhD

    Investigator Howard Hughes Medical Institute, Blais Chair of Molecular Medicine, Professor

    Focus:
    Investigation of the mechanism of RNA interference; investigation of how embryonic cells differentiate and communicate during development.

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  • Melissa J. Moore

    Melissa J. Moore, PhD

    Eleanor Eustis Farrington Chair in Cancer Research, Professor

    Focus:
    Post-transcriptional gene regulation in eukaryotes via mechanisms involving RNA.

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  • Athma A. Pai

    Athma A. Pai, PhD

    Assistant Professor

    Focus:
    Kinetics of RNA processing; genetic and genomic investigations of the dynamics of alternative mRNA splicing.

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  • Erik Sontheimer

    Erik Sontheimer, PhD

    Professor

    Focus:
    Biology and mechanism of RNA-based gene regulation; CRISPR interference; RNA-directed genome editing and gene control.

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  • Jonathan K. Watts

    Jonathan K. Watts, PhD

    Associate Professor

    Focus:
    Chemistry and chemical biology of oligonucleotides; Nucleic acid drug development.

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  • Wen Xue

    Wen Xue, PhD

    Assistant Professor

    Focus:
    Mouse models of cancer. Use CRISPR genome editing to functionally dissect cancer mutations in liver and lung cancer.

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  • Phillip Zamore

    Phillip Zamore, PhD

    Investigator Howard Hughes Medical Institute, Gretchen Stone Cook Professor of Biomedical Sciences, Chair and Professor

    Focus:
    Dissecting the RNAi and miRNA pathways.

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