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By interweaving nucleic acid scientists with clinicians dedicated to finding new cures, our goal is to create a new paradigm for organizing molecular research that enables the rapid application of new biological discoveries to solutions for unmet challenges in human health.
Andrei Korostelev, PhD, professor of RNA therapeutics, studies how bacteria can develop resistance to antibiotics, which has become a problem in treating infection. “Antibiotic resistance may cause the next global health crisis,” Dr. Korostelev said. Learn more about his work.
Save the dates for June 22-24, 2022 for the 4th annual RNA Therapeutics Symposium. Inclusivity and family support awards are available!
ScienceLIVE is an educational science outreach program for Worcester area middle schools. We provide opportunities for students to engage with our diverse postdoctoral and graduate student trainees through interactive, exciting virtual and hands-on STEM activities.
Preeclampsia (PE) affects up to 10% of human pregnancies worldwide and is a leading cause of maternal and fetal mortality and morbidity. Building off of the work of Melissa Moore's group, the Khvorova lab developed a framework for the chemical optimization of siRNAs for preeclampsia as well as other targets and clinical indications. This allows for more efficient placental delivery, silencing, as well as safety of sFLT1-targeting siRNAs. See more at Molecular Therapy Nucleic Acids on the Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1.
Meet Craig Mello, part of the RTI at UMass Chan, who was awarded the 2006 Nobel Prize in Physiology or Medicine, with Andrew Z. Fire, for the discovery of RNA interference. The discovery of RNAi has given scientists unprecedented opportunities to develop new life-saving therapies and advance our basic understanding of biology.
Worcester, known as the “Heart of the Commonwealth” is located in Central Massachusetts
