Michael Green, M.D., Ph.D.
Vice Provost for Strategic Research Initiatives
|M.D., Ph.D., 1981, Washington University School of Medicine|
|Postdoctoral research: Harvard University|
|Office:||University of Massachusetts Medical School
364 Plantation Street, LRB-628
Worcester, MA 01605
Alterations in gene regulation play a critical role in a wide range of human diseases. We are interested in the mechanisms that regulate gene expression in eukaryotes, and the role of gene expression in various human disease states, in particular cancer. To pursue these interests we use transcription-based approaches, functional screens (such as genome-wide loss-of-function RNAi- and CRISPR-based genetic screens) and proteomics methods to identify new genes, proteins and regulatory pathways that contribute to the disease state. These studies are intended to enhance our understanding of the molecular basis of disease and reveal potential new targets for therapeutic intervention. For a more detailed description of our research, click here.
A wide range of projects are available for rotating graduate students. Rotation projects are individually tailored to the research interests and objectives of each student. To discuss rotation projects, please contact Michael Green directly.
A wide range of projects are available for postdoctoral fellows. Projects are individually tailored to the research interests and objectives of each postdoctoral fellow. To discuss postdoctoral projects, please contact Michael Green directly.