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  • UMass Chan researchers develop dual therapeutic that holds promise as pancreatic cancer treatment

    UMass Chan researchers develop dual therapeutic that holds promise as pancreatic cancer treatment

    UMass Chan Medical School scientists Marcus Ruscetti, PhD, and Prabhani Atukorale, PhD, have developed a new, dual immunotherapy approach that may potentially change the way clinicians treat pancreatic cancer.  

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  • UMass Chan Early Independence Fellows program aims to develop future top investigators

    UMass Chan Early Independence Fellows program aims to develop future top investigators

    Two new donor-funded fellowships are being launched this year at UMass Chan to recruit recent postdoctoral scientists and, through intensive mentoring and resource support, foster their development as independent investigators. The fellowships align with the vision embodied in The Morningside Foundation’s transformational $175 million gift in 2021.  

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  • Summer Undergraduate Research Program provides hands-on experience, community collaboration

    Summer Undergraduate Research Program provides hands-on experience, community collaboration

    Thirty college students participated in the 2024 Summer Undergraduate Research Program at UMass Chan Medical School, refining their career goals through networking with peers and mentors, collaborative research and developing critical thinking skills.  

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MCCB Upcoming Events

  • Thursday, October 10, 2024

    IN-HOUSE SEMINAR

    Location: LRB 5th Floor Conference Room LRB 516
    Time: 12:00 PM - 1:00 PM

    Chandler Friend - Davis Lab

    Ewa Sroka, PhD - Kelliher Lab


  • Thursday, October 17, 2024

    IN-HOUSE SEMINAR

    Location: LRB 5th Floor Conference Room LRB 516
    Time: 12:00 PM - 1:00 PM

    UMASS RESEARCH RETREAT


  • Thursday, October 24, 2024

    IN-HOUSE SEMINAR

    Location: LRB 5th Floor Conference Room LRB 516
    Time: 12:00 PM - 1:00 PM

    Yong-Xu Wang, PhD


More events...

MCCB Publications

Liu P et al. (2024) Increasing intracellular dNTP levels improves prime editing efficiency.
Article | Wolfe Lab

Jo M et al. (2024) Flourescent tagging of endogenous IRS2 with an auxin-dependent degron to assess dynamic intracellular localization and function.
Article | Shaw Lab

Chibaya L et al. (2024) Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer.
Article | Ruscetti Lab

Liu H et al. (2024) CleanUpRNAseq:  An R/Bioconductor Package for Detecting and Correcting DNA Contamination in RNA-Seq Data.
Article |Bioinformatics Core

Flynn MJ et al. (2024) Calcineurin promotes adaptation to chronic stress through two distinct mechanisms.
Article | Benanti Lab

Kingsley SF et al. (2024) Glucose-fed microbiota alters C. elegans intestinal epithelium and increases susceptibility to multiple bacterial pathogens.
Article | Tissenbaum Lab

Ye T et al. (2024) Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma.
Article | Green Lab

O'Connor KW et al. (2024) The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance.
Article | Kelliher Lab

Mishra AK et al. (2024) Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer.
Article | Green Lab

Cong K et al. (2024) FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells.
Article | Cantor Lab

Lee N et al. (2024) Selenium reduction of ubiquinone via SQOR suppresses ferroptosis.
Article | Kim Lab

Kim S et al. (2024) Regulation of proteostasis and innate immunity via mitochondria-nuclear communication.
Article | Haynes Lab 

Roderick-Richardson JE et al. (2024) ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice.
Article | Kelliher Lab

Wang F et al. (2023) Roles of the Rlim-Rex1 axis during X chromosome inactivation in mice.
Article | Bach Lab

Mukhopadhyay D et al. (2023) The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing.
Article | Mercurio Lab

Doshi MB et al. (2023) Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells.
Article | Kim Lab

Ahmad MH et al. (2023) Runx1-R188Q germline mutation induces inflammation and predisposition to hematologic malignancies in mice.
Article | Castilla Lab

Shin M et al. (2023) Generation and application of endogenously floxed alleles for cell-specific knockout in zebrafish.
Article | Lawson Lab

Wang R et al. (2023) PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development.
Article | Baehrecke Lab

Liang SQ et al. (2023) Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag.
Article | Wolfe Lab

Xu Z et al. (2023) Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer.
A
rticle | Mercurio Lab

Conti MM et al. (2023) Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1. 
Article | Benanti Lab

Chibaya L et al. (2023) EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance.
Article | Ruscetti Lab

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