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Integrated Biomarkers Core

ABOUT US

The Integrated Biomarkers Core supports investigators in the acquisition and incorporation of Multiomics and Spatial Transcriptomics data into their research projects to ultimately reveal new insights into inflammatory diseases of multiple organ systems. We aim to:

  • Support the acquisition and integration of multiomics data points (single cell transcriptomics, proteomics, metabolomics) into signaling networks that characterize human disease progression
  • Create and supply spatial transcriptomics assays to understand constructed single cell networks within a spatial context
  • Build and optimize novel live tissue culture assays to validate and advance the mechanistic understanding of disease signaling pathways discovered and characterized through multiomics

 SERVICES

  • Access to Olink proteomics analysis for human fluids
  • Spatial transcriptomics using Multiplexed error-robust fluorescence in situ hybridization (merFISH) – SCOPE core
  • Access to merFISH assays in human tissues
  • Optimization and application of live tissue sectioning through Compresstome and culture for human tissue assays

CONTACT US

Please feel free to reach out to us to discuss your research project needs, and let us know how we can be of assistance.

Email: John.Harris@umassmed.edu