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Publications 2023

Adams, G., Moreno, G.K., Petros, B.A., Uddin, R., Levine, Z., Kotzen, B., Messer, K., Dobbins, S.T., DeRuff, K.C., Loreth, C., et al. (2023). The 2022 RSV surge was driven by multiple viral lineages. medRxiv. doi:10.1101/2023.01.04.23284195. PMCID: PMC9844019

Adler, B.A., Trinidad, M.I., Bellieny-Rabelo, D., Zhang, E., Karp, H.M., Skopintsev, P., Thornton, B.W., Weissman, R.F., Yoon, P.H., Chen, L., et al. (2023). CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes. Nucleic Acids Res.  Online ahead of print doi:10.1093/nar/gkad890.

Alexander, K.D., Ramachandran, S., Biswas, K., Lambert, C.M., Russell, J., Oliver, D.B., Armstrong, W., Rettler, M., Liu, S., Doitsidou, M., et al. (2023). The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling. Nat Commun 14, 7520. doi:10.1038/s41467-023-43281-4. PMCID: PMC10657367

Andolina, C., Ramjith, J., Rek, J., Lanke, K., Okoth, J., Grignard, L., Arinaitwe, E., Briggs, J., Bailey, J., Aydemir, O., et al. (2023). Plasmodium falciparum gametocyte carriage in longitudinally monitored incident infections is associated with duration of infection and human host factors. Sci Rep 13, 7072. doi:10.1038/s41598-023-33657-3. PMCID: PMC10150352

Andrews, G., Fan, K., Pratt, H.E., Phalke, N., Zoonomia Consortium section, s., Karlsson, E.K., Lindblad-Toh, K., Gazal, S., Moore, J.E., and Weng, Z. (2023). Mammalian evolution of human cis-regulatory elements and transcription factor binding sites. Science 380, eabn7930. doi:10.1126/science.abn7930.

Aroian, R.V., Loukas, A., and Martin, R.J. (2023). Anthelmintics V: Drugs, resistance, and vaccines. Int J Parasitol 53, 391-392. doi:10.1016/j.ijpara.2023.05.004. PMCID: PMC10226775

Aryee, K.E., Shultz, L.D., Burzenski, L.M., Greiner, D.L., and Brehm, M.A. (2023). NOD-scid IL2rgammanull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity. J Leukoc Biol 113, 418-433. doi:10.1093/jleuko/qiac020.

Baier, A.S., Gioacchini, N., Eek, P., Tan, S., and Peterson, C.L. (2023). Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. Res Sq. doi:10.21203/ PMCID: PMC10402270

Bakey, Z., Cabrera, O.A., Hoefele, J., Antony, D., Wu, K., Stuck, M.W., Micha, D., Eguether, T., Smith, A.O., van der Wel, N.N., et al. (2023). IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans. PLoS Genet 19, e1010796. doi:10.1371/journal.pgen.1010796.  PMCID: PMC10298753

Bamidele, N., Zhang, H., Dong, X., Gaston, N., Cheng, H., Kelly, K., Watts, J.K., Xie, J., Gao, G., and Sontheimer, E.J. (2023). Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope. bioRxiv. doi:10.1101/2023.04.14.536905. PMCID: PMC10153126

Bryll, A.R., and Peterson, C.L. (2023). The circular logic of mRNA homeostasis. Transcription 14, 18-26. doi:10.1080/21541264.2023.2183684. PMCID: PMC10353332

Cao, J., Yu, T., Xu, B., Hu, Z., Zhang, X.O., Theurkauf, W.E., and Weng, Z. (2023). Epigenetic and chromosomal features drive transposon insertion in Drosophila melanogaster. Nucleic Acids Res 51, 2066-2086. doi:10.1093/nar/gkad054. PMCID: PMC10018349

Ceol, C.J. (2023). Microenvironmental GABA Signaling Regulates Melanomagenesis through Reciprocal Melanoma-Keratinocyte Communication. Cancer Discov 13, 2128-2130. doi:10.1158/2159-8290.CD-23-0843.

Chen, Y., Lei, X., Jiang, Z., Humphries, F., Parsi, K.M., Mustone, N.J., Ramos, I., Mutetwa, T., Fernandez-Sesma, A., Maehr, R., et al. (2023). Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates. Proc Natl Acad Sci U S A 120, e2308355120. doi:10.1073/pnas.2308355120. PMCID: PMC10666094

Chen, Z., Kwan, S.Y., Mir, A., Hazeltine, M., Shin, M., Liang, S.Q., Chan, I.L., Kelly, K., Ghanta, K.S., Gaston, N., et al. (2023). A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors. CRISPR J 6, 570-582. doi:10.1089/crispr.2023.0048. PMCID: PMC10753986

Chibaya, L., Lusi, C.F., DeMarco, K.D., Kane, G.I., Brassil, M.L., Parikh, C.N., Murphy, K.C., Li, J., Naylor, T.E., Cerrutti, J., et al. (2023). Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer. bioRxiv. doi:10.1101/2023.09.18.558307. PMCID: PMC10542133

Chibaya, L., Murphy, K.C., DeMarco, K.D., Gopalan, S., Liu, H., Parikh, C.N., Lopez-Diaz, Y., Faulkner, M., Li, J., Morris, J.P.t., et al. (2023). EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance. Nat Cancer 4, 872-892. doi:10.1038/s43018-023-00553-8. PMCID: PMC10516132

Chio, U.S., Rechiche, O., Bryll, A.R., Zhu, J., Feldman, J.L., Peterson, C.L., Tan, S., and Armache, J.P. (2023). Cryo-EM structure of the human Sirtuin 6-nucleosome complex. bioRxiv. doi:10.1101/2023.03.17.533206. PMCID: PMC10055229

Chio, U.S., Rechiche, O., Bryll, A.R., Zhu, J., Leith, E.M., Feldman, J.L., Peterson, C.L., Tan, S., and Armache, J.P. (2023). Cryo-EM structure of the human Sirtuin 6-nucleosome complex. Sci Adv 9, eadf7586. doi:10.1126/sciadv.adf7586. PMCID: PMC10104460

Christmas, M.J., Kaplow, I.M., Genereux, D.P., Dong, M.X., Hughes, G.M., Li, X., Sullivan, P.F., Hindle, A.G., Andrews, G., Armstrong, J.C., et al. (2023). Evolutionary constraint and innovation across hundreds of placental mammals. Science 380, eabn3943. doi:10.1126/science.abn3943. PMCID: PMC10250106

Chuprin, J., Buettner, H., Seedhom, M.O., Greiner, D.L., Keck, J.G., Ishikawa, F., Shultz, L.D., and Brehm, M.A. (2023). Humanized mouse models for immuno-oncology research. Nat Rev Clin Oncol 20, 192-206. doi:10.1038/s41571-022-00721-2. PMCID: PMC10593256

Connelly, S.V., Brazeau, N.F., Msellem, M., Ngasala, B.E., Aydemir, O., Goel, V., Niare, K., Giesbrecht, D.J., Popkin-Hall, Z.R., Hennelly, C.M., et al. (2023). Strong isolation by distance and evidence of population microstructure reflect ongoing Plasmodium falciparum transmission in Zanzibar. medRxiv. doi:10.1101/2023.02.15.23285960. PMCID: PMC9980253

Dagdeviren, S., Hoang, M.F., Sarikhani, M., Meier, V., Benoit, J.C., Okawa, M.C., Melnik, V.Y., Ricci-Blair, E.M., Foot, N., Friedline, R.H., et al. (2023). An insulin-regulated arrestin domain protein controls hepatic glucagon action. J Biol Chem 299, 105045. doi:10.1016/j.jbc.2023.105045. PMCID: PMC10413355

Derr, A.G., Arowosegbe, A., Satish, B., Redick, S.D., Qaisar, N., Guo, Z., Vanderleeden, E., Trombly, M.I., Baer, C.E., Harlan, D.M., et al. (2023). An Early Islet Transcriptional Signature Is Associated With Local Inflammation in Autoimmune Diabetes. Diabetes 72, 261-274. doi:10.2337/db22-0521. PMCID: PMC9871196

Devarajan, P., Vong, A.M., Castonguay, C.H., Silverstein, N.J., Kugler-Umana, O., Bautista, B.L., Kelly, K.A., Luban, J., and Swain, S.L. (2023). Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15. Cell Rep 42, 113182. doi:10.1016/j.celrep.2023.113182.

Doloff, J.C., Ma, M., Sadraei, A., Tam, H.H., Farah, S., Hollister-Lock, J., Vegas, A.J., Veiseh, O., Quiroz, V.M., Rakoski, A., et al. (2023). Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response. Sci Adv 9, eade9488. doi:10.1126/sciadv.ade9488. PMCID: PMC10275594

Doxsey, D.D., Tettoni, S.D., Egri, S.B., and Shen, K. (2023). Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells. J Biol Chem 299, 104880. doi:10.1016/j.jbc.2023.104880. PMCID: PMC10316081

Egri, S.B., Wang, X., Diaz-Salinas, M.A., Luban, J., Dudkina, N.V., Munro, J.B., and Shen, K. (2023). Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination. Nat Commun 14, 2527. doi:10.1038/s41467-023-38251-9. PMCID: PMC10154187

Fanelli, M.J., Welsh, C.M., Lui, D.S., Smulan, L.J., and Walker, A.K. (2023). Immunity-linked genes are stimulated by a membrane stress pathway linked to Golgi function and the ARF-1 GTPase. Sci Adv 9, eadi5545. doi:10.1126/sciadv.adi5545. PMCID: PMC10699786

Ferreira, V., Folgueira, C., Garcia-Altares, M., Guillen, M., Ruiz-Rosario, M., DiNunzio, G., Garcia-Martinez, I., Alen, R., Bookmeyer, C., Jones, J.G., et al. (2023). Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition. Redox Biol 63, 102741. doi:10.1016/j.redox.2023.102741. PMCID: PMC10225935

Foley, N.M., Mason, V.C., Harris, A.J., Bredemeyer, K.R., Damas, J., Lewin, H.A., Eizirik, E., Gatesy, J., Karlsson, E.K., Lindblad-Toh, K., et al. (2023). A genomic timescale for placental mammal evolution. Science 380, eabl8189. doi:10.1126/science.abl8189. PMCID: PMC10233747

Francis, R.J.B., San Agustin, J.T., Szabo Rogers, H.L., Cui, C., Jonassen, J.A., Eguether, T., Follit, J.A., Lo, C.W., and Pazour, G.J. (2023). Autonomous and non-cell autonomous role of cilia in structural birth defects in mice. PLoS Biol 21, e3002425. doi:10.1371/journal.pbio.3002425. PMCID: PMC10735189

Frantz, W.T., Iyengar, S., Neiswender, J., Cousineau, A., Maehr, R., and Ceol, C.J. (2023). Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish. Elife 12. doi:10.7554/eLife.78942. PMCID: PMC10139689

Godbole, A.A., Gopalan, S., Nguyen, T.K., Munden, A.L., Lui, D.S., Fanelli, M.J., Vo, P., Lewis, C.A., Spinelli, J.B., Fazzio, T.G., and Walker, A.K. (2023). S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress. Elife 12. doi:10.7554/eLife.79511. PMCID: PMC9984191

Gong, J., Nirala, N.K., Chen, J., Wang, F., Gu, P., Wen, Q., Ip, Y.T., and Xiang, Y. (2023). TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila. Sci Adv 9, eadc9660. doi:10.1126/sciadv.adc9660. PMCID: PMC10208578

Goo, B.S., Mun, D.J., Kim, S., Nhung, T.T.M., Lee, S.B., Woo, Y., Kim, S.J., Suh, B.K., Park, S.J., Lee, H.E., et al. (2023). Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex. Mol Psychiatry 28, 856-870. doi:10.1038/s41380-022-01856-5. PMCID: PMC9908555

Guertin, D.A., and Wellen, K.E. (2023). Acetyl-CoA metabolism in cancer. Nat Rev Cancer 23, 156-172. doi:10.1038/s41568-022-00543-5.

Guilherme, A., Rowland, L.A., Wang, H., and Czech, M.P. (2023). The adipocyte supersystem of insulin and cAMP signaling. Trends Cell Biol 33, 340-354. doi:10.1016/j.tcb.2022.07.009. PMCID: PMC10339226

Guilherme, A., Rowland, L.A., Wetoska, N., Tsagkaraki, E., Santos, K.B., Bedard, A.H., Henriques, F., Kelly, M., Munroe, S., Pedersen, D.J., et al. (2023). Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program. Cell Rep 42, 112488. doi:10.1016/j.celrep.2023.112488. PMCID: PMC10286105

Guney, M.H., Nagalekshmi, K., McCauley, S.M., Carbone, C., Aydemir, O., and Luban, J. (2023). IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus. bioRxiv. doi:10.1101/2023.11.17.567619. PMCID: PMC10680824

Gupta, M., and Pazour, G.J. (2023). Intraflagellar transport: A critical player in photoreceptor development and the pathogenesis of retinal degenerative diseases. Cytoskeleton (Hoboken). doi:10.1002/cm.21823.

Haley, J.A., Jang, C., and Guertin, D.A. (2023). A new era of understanding in vivo metabolic flux in thermogenic adipocytes. Curr Opin Genet Dev 83, 102112. doi:10.1016/j.gde.2023.102112.

Hariharan, V.N., Shin, M., Chang, C.W., O'Reilly, D., Biscans, A., Yamada, K., Guo, Z., Somasundaran, M., Tang, Q., Monopoli, K., et al. (2023). Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection. Proc Natl Acad Sci U S A 120, e2219523120. doi:10.1073/pnas.2219523120. PMCID: PMC10089225

Harmon, C., Zaborowski, A., Moore, H., St Louis, P., Slattery, K., Duquette, D., Scanlan, J., Kane, H., Kunkemoeller, B., McIntyre, C.L., et al. (2023). gammadelta T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors. Nat Cancer 4, 1122-1137. doi:10.1038/s43018-023-00589-w.

Herbert, C., Manabe, Y.C., Filippaios, A., Lin, H., Wang, B., Achenbach, C., Kheterpal, V., Hartin, P., Suvarna, T., Harman, E., et al. (2023). Differential Viral Dynamics by Sex and Body Mass Index During Acute SARS-CoV-2 Infection: Results from a Longitudinal Cohort Study. Clin Infect Dis. doi:10.1093/cid/ciad701.

Ho, S., Rice, N.P., Yu, T., Weng, Z., and Theurkauf, W.E. (2023). Aub, Vasa and Armi localization to phase separated nuage is dispensable for piRNA biogenesis and transposon silencing in Drosophila. bioRxiv. doi:10.1101/2023.07.25.549160. PMCID: PMC10402007

Honeywell, M.E., Isidor, M.S., Harper, N.W., Fontana, R.E., Cruz-Gordillo, P., Porto, S.A., Fraser, C.S., Sarosiek, K.A., Guertin, D.A., Spinelli, J.B., and Lee, M.J. (2023). p53 controls choice between apoptotic and non-apoptotic death following DNA damage. bioRxiv. doi:10.1101/2023.01.17.524444. PMCID: PMC9882237

Huang, L., Liu, P., Du, Y., Pan, D., Lee, A., Wolfe, S.A., and Wang, Y.X. (2023). A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite. bioRxiv. doi:10.1101/2023.09.12.557454. PMCID: PMC10515849

Huang, Y.S., Mendez, R., Fernandez, M., and Richter, J.D. (2023). CPEB and translational control by cytoplasmic polyadenylation: impact on synaptic plasticity, learning, and memory. Mol Psychiatry 28, 2728-2736. doi:10.1038/s41380-023-02088-x. PMCID: PMC10620108

Itah, Z., Chaudhry, S., Raju Ponny, S., Aydemir, O., Lee, A., Cavanagh-Kyros, J., Tournier, C., Muller, W.J., and Davis, R.J. (2023). HER2-driven breast cancer suppression by the JNK signaling pathway. Proc Natl Acad Sci U S A 120, e2218373120. doi:10.1073/pnas.2218373120. PMCID: PMC9942916

Jain, A., Govindan, R., Berkman, A.R., Luban, J., Diaz-Salinas, M.A., Durham, N.D., and Munro, J.B. (2023). Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome. PLoS Pathog 19, e1011848. doi:10.1371/journal.ppat.1011848. PMCID: PMC10727438

Jiang, H.C., Park, S.J., Wang, I.H., Bear, D.M., Nowlan, A., and Greer, P.L. (2023). CD20 is a mammalian odorant receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predators. Res Sq. doi:10.21203/ PMCID: PMC10543371

Jung, S., Shah, S., Han, G., and Richter, J.D. (2023). FMRP deficiency leads to multifactorial dysregulation of splicing and mislocalization of MBNL1 to the cytoplasm. PLoS Biol 21, e3002417. doi:10.1371/journal.pbio.3002417. PMCID: PMC10721184

Kearns, N.A., Lobo, M., Genga, R.M.J., Abramowitz, R.G., Parsi, K.M., Min, J., Kernfeld, E.M., Huey, J.D., Kady, J., Hennessy, E., et al. (2023). Generation and molecular characterization of human pluripotent stem cell-derived pharyngeal foregut endoderm. Dev Cell 58, 1801-1818 e1815. doi:10.1016/j.devcel.2023.08.024. PMCID: PMC10637111

Keough, K.C., Whalen, S., Inoue, F., Przytycki, P.F., Fair, T., Deng, C., Steyert, M., Ryu, H., Lindblad-Toh, K., Karlsson, E., et al. (2023). Three-dimensional genome rewiring in loci with human accelerated regions. Science 380, eabm1696. doi:10.1126/science.abm1696.

Ketchesin, K.D., Becker-Krail, D.D., Xue, X., Wilson, R.S., Lam, T.T., Williams, K.R., Nairn, A.C., Tseng, G.C., and Logan, R.W. (2023). Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. J Proteome Res 22, 2377-2390. doi:10.1021/acs.jproteome.3c00126. PMCID: PMC10392613

Kraus, C., and Sontheimer, E.J. (2023). Applications of Anti-CRISPR Proteins in Genome Editing and Biotechnology. J Mol Biol 435, 168120. doi:10.1016/j.jmb.2023.168120.

Kreutzfeld, O., Tumwebaze, P.K., Okitwi, M., Orena, S., Byaruhanga, O., Katairo, T., Conrad, M.D., Rasmussen, S.A., Legac, J., Aydemir, O., et al. (2023). Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline. Microbiol Spectr 11, e0523622. doi:10.1128/spectrum.05236-22. PMCID: PMC10269555

Kulkarni, A., Ewen-Campen, B., Terao, K., Matsumoto, Y., Li, Y., Watanabe, T., Kao, J.A., Parhad, S.S., Ylla, G., Mizunami, M., and Extavour, C.G. (2023). oskar acts with the transcription factor Creb to regulate long-term memory in crickets. Proc Natl Acad Sci U S A 120, e2218506120. doi:10.1073/pnas.2218506120. PMCID: PMC10214185

Landshammer, A., Bolondi, A., Kretzmer, H., Much, C., Buschow, R., Rose, A., Wu, H.J., Mackowiak, S.D., Braendl, B., Giesselmann, P., et al. (2023). T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. Elife 12. doi:10.7554/eLife.83077. PMCID: PMC9889090

Lee, L., Yu, H., Jia, B.B., Jussila, A., Zhu, C., Chen, J., Xie, L., Hafner, A., Mishra, S., Wang, D.D., et al. (2023). SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data. Nat Commun 14, 4873. doi:10.1038/s41467-023-40658-3. PMCID: PMC10423204

Leylek, O., Honeywell, M.E., Lee, M.J., Hemann, M.T., and Ozcan, G. (2023). Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy. bioRxiv. doi:10.1101/2023.10.07.561351. PMCID: PMC10592690

Li, H., Gazzola, D., Hu, Y., and Aroian, R.V. (2023). An efficient method for viable cryopreservation and recovery of hookworms and other gastrointestinal nematodes in the laboratory. Int J Parasitol 53, 451-458. doi:10.1016/j.ijpara.2023.05.001. PMCID: PMC10330584

Liang, S.Q., Liu, P., Ponnienselvan, K., Suresh, S., Chen, Z., Kramme, C., Chatterjee, P., Zhu, L.J., Sontheimer, E.J., Xue, W., and Wolfe, S.A. (2023). Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag. Nat Methods 20, 898-907. doi:10.1038/s41592-023-01859-2.

Liu, H., Caliz, A.D., Learnard, H., Koupenova, M., Keaney, J.F., Kant, S., Zhu, L.J., and Vertii, A. (2023). Inflammatory stress-mediated chromatin changes underlie dysfunction in endothelial cells. bioRxiv. doi:10.1101/2023.10.11.561959. PMCID: PMC10614786

Luo, S., Lyu, Z., Ge, L., Li, Y., Liu, Y., Yuan, Y., Zhao, R., Huang, L., Zhao, J., Huang, H., and Luo, Y. (2023). Ataxia Telangiectasia Mutated Protects against Lipopolysaccaride-Induced Blood-Brain Barrier Disruption by Regulating Atk/Drp1-Mediated Mitochondrial Homeostasis. Shock 60, 100-109. doi:10.1097/SHK.0000000000002139. PMCID: PMC10417231

Malvi, P., Chava, S., Cai, G., Hu, K., Zhu, L.J., Edwards, Y.J.K., Green, M.R., Gupta, R., and Wajapeyee, N. (2023). HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B. Cell Rep Med 4, 101285. doi:10.1016/j.xcrm.2023.101285. PMCID: PMC10694669

McGee, A.V., Liu, Y.V., Griffith, A.L., Szegletes, Z.M., Wen, B., Kraus, C., Miller, N.W., Steger, R.J., Velasco, B.E., Bosch, J.A., et al. (2023). Modular vector assembly enables rapid assessment of emerging CRISPR technologies. bioRxiv. doi:10.1101/2023.10.25.564061. PMCID: PMC10634825

Mirza, Z., Walhout, A.J.M., and Ambros, V. (2023). A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans. Cell Rep 42, 113189. doi:10.1016/j.celrep.2023.113189.

Mou, H., Eskiocak, O., Ozler, K.A., Gorman, M., Yue, J., Jin, Y., Wang, Z., Gao, Y., Janowitz, T., Meyer, H.V., et al. (2023). CRISPR-induced exon skipping of beta-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer. J Pathol 259, 415-427. doi:10.1002/path.6054. PMCID: PMC10273193

Nandy, A., Helderman, R.C.M., Thapa, S., Jayapalan, S., Richards, A., Narayani, N., Czech, M.P., Rosen, C.J., and Rendina-Ruedy, E. (2023). Lipolysis supports bone formation by providing osteoblasts with endogenous fatty acid substrates to maintain bioenergetic status. Bone Res 11, 62. doi:10.1038/s41413-023-00297-2. PMCID: PMC10673934

Odongo, L., Zadrozny, K.K., Diehl, W.E., Luban, J., White, J.M., Ganser-Pornillos, B.K., Tamm, L.K., and Pornillos, O. (2023). Purification and structure of luminal domain C of human Niemann-Pick C1 protein. Acta Crystallogr F Struct Biol Commun 79, 45-50. doi:10.1107/S2053230X23000705. PMCID: PMC9903137

Osmanski, A.B., Paulat, N.S., Korstian, J., Grimshaw, J.R., Halsey, M., Sullivan, K.A.M., Moreno-Santillan, D.D., Crookshanks, C., Roberts, J., Garcia, C., et al. (2023). Insights into mammalian TE diversity through the curation of 248 genome assemblies. Science 380, eabn1430. doi:10.1126/science.abn1430.

Park, G., Haley, J.A., Le, J., Jung, S.M., Fitzgibbons, T.P., Korobkina, E.D., Li, H., Fluharty, S.M., Chen, Q., Spinelli, J.B., et al. (2023). Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis. Nat Metab 5, 1204-1220. doi:10.1038/s42255-023-00825-8. PMCID: PMC10696589

Park, S.J., Greer, P.L., and Lee, N. (2023). From odor to oncology: non-canonical odorant receptors in cancer. Oncogene. doi:10.1038/s41388-023-02908-y.

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