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Publications 2013

Jurczyk A, Diiorio P, Brostowin D, Leehy L, Yang C, Urano F, Harlan DM, Shultz LD, Greiner DL, Bortell R. Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rgamma(null) mice treated with alogliptin. Diabetes Metab Syndr Obes. 2013;6:493-9. Epub 2014/01/01. doi: 10.2147/DMSO.S53154. PubMed PMID: 24376359; PMCID: PMC3864939. https://www.ncbi.nlm.nih.gov/pubmed/24376359

Amano SU, Cohen JL, Vangala P, Tencerova M, Nicoloro SM, Yawe JC, Shen Y, Czech MP, Aouadi M. Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation. Cell Metab. 2014;19(1):162-71. Epub 2014/01/01. doi: 10.1016/j.cmet.2013.11.017. PubMed PMID: 24374218; PMCID: PMC3931314. https://www.ncbi.nlm.nih.gov/pubmed/24374218

Yang K, Shrestha S, Zeng H, Karmaus PW, Neale G, Vogel P, Guertin DA, Lamb RF, Chi H. T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming. Immunity. 2013;39(6):1043-56. Epub 2013/12/10. doi: 10.1016/j.immuni.2013.09.015. PubMed PMID: 24315998; PMCID: PMC3986063.
https://www.ncbi.nlm.nih.gov/pubmed/24315998

Usami Y, Gottlinger H. HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity. Cell Rep. 2013;5(3):802-12. Epub 2013/11/12. doi: 10.1016/j.celrep.2013.09.028. PubMed PMID: 24209751; PMCID: PMC3864691. https://www.ncbi.nlm.nih.gov/pubmed/24209751

Gabriel LR, Wu S, Kearney P, Bellve KD, Standley C, Fogarty KE, Melikian HE. Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton. J Neurosci. 2013;33(45):17836-46. Epub 2013/11/08. doi: 10.1523/JNEUROSCI.3284-13.2013. PubMed PMID: 24198373; PMCID: PMC3818556.
https://www.ncbi.nlm.nih.gov/pubmed/24198373

Vernia S, Cavanagh-Kyros J, Barrett T, Jung DY, Kim JK, Davis RJ. Diet-induced obesity mediated by the JNK/DIO2 signal transduction pathway. Genes Dev. 2013;27(21):2345-55. Epub 2013/11/05. doi: 10.1101/gad.223800.113. PubMed PMID: 24186979; PMCID: PMC3828520.
https://www.ncbi.nlm.nih.gov/pubmed/24186979

Jung DY, Chalasani U, Pan N, Friedline RH, Prosdocimo DA, Nam M, Azuma Y, Maganti R, Yu K, Velagapudi A, O'Sullivan-Murphy B, Sartoretto JL, Jain MK, Cooper MP, Urano F, Kim JK, Gray S. KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance. PLoS One. 2013;8(10):e77851. Epub 2013/10/30. doi: 10.1371/journal.pone.0077851. PubMed PMID: 24167585; PMCID: PMC3805598.
https://www.ncbi.nlm.nih.gov/pubmed/24167585

Brehm MA, Shultz LD, Luban J, Greiner DL. Overcoming current limitations in humanized mouse research. J Infect Dis. 2013;208 Suppl 2:S125-30. Epub 2013/10/30. doi: 10.1093/infdis/jit319. PubMed PMID: 24151318; PMCID: PMC3807974. https://www.ncbi.nlm.nih.gov/pubmed/24151318

Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M, Jr., Chun TW, Strain M, Richman D, Luzuriaga K. Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med. 2013;369(19):1828-35. Epub 2013/10/25. doi: 10.1056/NEJMoa1302976. PubMed PMID: 24152233; PMCID: PMC3954754. https://www.ncbi.nlm.nih.gov/pubmed/24152233

Yang C, Jurczyk A, diIorio P, Norowski E, Brehm MA, Grant CW, Guberski DL, Greiner DL, Bortell R. Salicylate prevents virus-induced type 1 diabetes in the BBDR rat. PLoS One. 2013;8(10):e78050. Epub 2013/10/23. doi: 10.1371/journal.pone.0078050. PubMed PMID: 24147110; PMCID: PMC3797740. https://www.ncbi.nlm.nih.gov/pubmed/24147110

Fuxman Bass JI, Tamburino AM, Mori A, Beittel N, Weirauch MT, Reece-Hoyes JS, Walhout AJ. Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters. Nucleic Acids Res. 2014;42(1):153-62. Epub 2013/09/27. doi: 10.1093/nar/gkt858. PubMed PMID: 24068555; PMCID: PMC3874175.
https://www.ncbi.nlm.nih.gov/pubmed/24068555 

Cheng W, Ip YT, Xu Z. Gudu, an Armadillo repeat-containing protein, is required for spermatogenesis in Drosophila. Gene. 2013;531(2):294-300. Epub 2013/09/24. doi: 10.1016/j.gene.2013.08.080. PubMed PMID: 24055424; PMCID: PMC3839114. https://www.ncbi.nlm.nih.gov/pubmed/24055424

Peterson CL, Almouzni G. Nucleosome dynamics as modular systems that integrate DNA damage and repair. Cold Spring Harb Perspect Biol. 2013;5(9). Epub 2013/09/05. doi: 10.1101/cshperspect.a012658. PubMed PMID: 24003210; PMCID: PMC3753706.
https://www.ncbi.nlm.nih.gov/pubmed/24003210

Kant S, Barrett T, Vertii A, Noh YH, Jung DY, Kim JK, Davis RJ. Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity. Cell Rep. 2013;4(4):681-8. Epub 2013/08/21. doi: 10.1016/j.celrep.2013.07.019. PubMed PMID: 23954791; PMCID: PMC3769115. https://www.ncbi.nlm.nih.gov/pubmed/23954791

Malaby AW, van den Berg B, Lambright DG. Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors. Proc Natl Acad Sci U S A. 2013;110(35):14213-8. Epub 2013/08/14. doi: 10.1073/pnas.1301883110. PubMed PMID: 23940353; PMCID: PMC3761562. https://www.ncbi.nlm.nih.gov/pubmed/23940353

Danai LV, Guilherme A, Guntur KV, Straubhaar J, Nicoloro SM, Czech MP. Map4k4 suppresses Srebp-1 and adipocyte lipogenesis independent of JNK signaling. J Lipid Res. 2013;54(10):2697-707. Epub 2013/08/09. doi: 10.1194/jlr.M038802. PubMed PMID: 23924694; PMCID: PMC3770083.
https://www.ncbi.nlm.nih.gov/pubmed/23924694

Kearns NA, Genga RM, Ziller M, Kapinas K, Peters H, Brehm MA, Meissner A, Maehr R. Generation of organized anterior foregut epithelia from pluripotent stem cells using small molecules. Stem Cell Res. 2013;11(3):1003-12. Epub 2013/08/07. doi: 10.1016/j.scr.2013.06.007. PubMed PMID: 23917481.
https://www.ncbi.nlm.nih.gov/pubmed/23917481

Hong EG, Kim BW, Jung DY, Kim JH, Yu T, Seixas Da Silva W, Friedline RH, Bianco SD, Seslar SP, Wakimoto H, Berul CI, Russell KS, Lee KW, Larsen PR, Bianco AC, Kim JK. Cardiac expression of human type 2 iodothyronine deiodinase increases glucose metabolism and protects against doxorubicin-induced cardiac dysfunction in male mice. Endocrinology. 2013;154(10):3937-46. Epub 2013/07/19. doi: 10.1210/en.2012-2261. PubMed PMID: 23861374; PMCID: PMC4411365. https://www.ncbi.nlm.nih.gov/pubmed/23861374

Watanabe S, Peterson CL. Chromatin dynamics: flipping the switch on a chromatin remodeling machine. Cell Cycle. 2013;12(15):2337-8. Epub 2013/07/17. doi: 10.4161/cc.25704. PubMed PMID: 23856580; PMCID: PMC3841306. https://www.ncbi.nlm.nih.gov/pubmed/23856580

Mishra AK, Del Campo CM, Collins RE, Roy CR, Lambright DG. The Legionella pneumophila GTPase activating protein LepB accelerates Rab1 deactivation by a non-canonical hydrolytic mechanism. J Biol Chem. 2013;288(33):24000-11. Epub 2013/07/04. doi: 10.1074/jbc.M113.470625. PubMed PMID: 23821544; PMCID: PMC3745345. https://www.ncbi.nlm.nih.gov/pubmed/23821544

Bennett G, Papamichos-Chronakis M, Peterson CL. DNA repair choice defines a common pathway for recruitment of chromatin regulators. Nat Commun. 2013;4:2084. Epub 2013/07/03. doi: 10.1038/ncomms3084. PubMed PMID: 23811932; PMCID: PMC3731036.
https://www.ncbi.nlm.nih.gov/pubmed/23811932 

Corvera S, Gealekman O. Adipose tissue angiogenesis: impact on obesity and type-2 diabetes. Biochim Biophys Acta. 2014;1842(3):463-72. Epub 2013/06/19. doi: 10.1016/j.bbadis.2013.06.003. PubMed PMID: 23770388; PMCID: PMC3844681. https://www.ncbi.nlm.nih.gov/pubmed/23770388 

Brehm MA, Jouvet N, Greiner DL, Shultz LD. Humanized mice for the study of infectious diseases. Curr Opin Immunol. 2013;25(4):428-35. Epub 2013/06/12. doi: 10.1016/j.coi.2013.05.012. PubMed PMID: 23751490; PMCID: PMC3775881. https://www.ncbi.nlm.nih.gov/pubmed/23751490

Sanchez-Gurmaches J, Guertin DA. Adipocyte lineages: tracing back the origins of fat. Biochim Biophys Acta. 2014;1842(3):340-51. Epub 2013/06/12. doi: 10.1016/j.bbadis.2013.05.027. PubMed PMID: 23747579; PMCID: PMC3805734. https://www.ncbi.nlm.nih.gov/pubmed/23747579 

Aouadi M, Tencerova M, Vangala P, Yawe JC, Nicoloro SM, Amano SU, Cohen JL, Czech MP. Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice. Proc Natl Acad Sci U S A. 2013;110(20):8278-83. Epub 2013/05/01. doi: 10.1073/pnas.1300492110. PubMed PMID: 23630254; PMCID: PMC3657808. https://www.ncbi.nlm.nih.gov/pubmed/23630254 

Lopes da Rosa J, Bajaj V, Spoonamore J, Kaufman PD. A small molecule inhibitor of fungal histone acetyltransferase Rtt109. Bioorg Med Chem Lett. 2013;23(10):2853-9. Epub 2013/04/17. doi: 10.1016/j.bmcl.2013.03.112. PubMed PMID: 23587423; PMCID: PMC3654155.
https://www.ncbi.nlm.nih.gov/pubmed/23587423 

Watanabe S, Radman-Livaja M, Rando OJ, Peterson CL. A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme. Science. 2013;340(6129):195-9. Epub 2013/04/13. doi: 10.1126/science.1229758. PubMed PMID: 23580526; PMCID: PMC3727404.
https://www.ncbi.nlm.nih.gov/pubmed/23580526

Watson E, MacNeil LT, Arda HE, Zhu LJ, Walhout AJM. Integration of metabolic and gene regulatory networks modulates the C. elegans dietary response. Cell. 2013;153(1):253-66. Epub 2013/04/02. doi: 10.1016/j.cell.2013.02.050. PubMed PMID: 23540702; PMCID: PMC3817025.
https://www.ncbi.nlm.nih.gov/pubmed/23540702

Strambio-De-Castilla C. Jumping over the fence: RNA nuclear export revisited. Nucleus. 2013;4(2):95-9. Epub 2013/03/27. doi: 10.4161/nucl.24237. PubMed PMID: 23528257; PMCID: PMC3621751.
https://www.ncbi.nlm.nih.gov/pubmed/23528257

Schiel JA, Childs C, Prekeris R. Endocytic transport and cytokinesis: from regulation of the cytoskeleton to midbody inheritance. Trends Cell Biol. 2013;23(7):319-27. Epub 2013/03/26. doi: 10.1016/j.tcb.2013.02.003. PubMed PMID: 23522622; PMCID: PMC4228945.
https://www.ncbi.nlm.nih.gov/pubmed/23522622

Hehnly H, Hung HF, Doxsey S. One among many: ODF2 isoform 9, a.k.a. Cenexin-1, is required for ciliogenesis. Cell Cycle. 2013;12(7):1021. Epub 2013/03/21. doi: 10.4161/cc.24330. PubMed PMID: 23511168; PMCID: PMC3646858. https://www.ncbi.nlm.nih.gov/pubmed/23511168

Follit JA, Pazour GJ. Analysis of ciliary membrane protein dynamics using SNAP technology. Methods Enzymol. 2013;524:195-204. Epub 2013/03/19. doi: 10.1016/B978-0-12-397945-2.00011-1. PubMed PMID: 23498741; PMCID: PMC3844868. https://www.ncbi.nlm.nih.gov/pubmed/23498741

Guo CA, Kogan S, Amano SU, Wang M, Dagdeviren S, Friedline RH, Aouadi M, Kim JK, Czech MP. CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance. Am J Physiol Endocrinol Metab. 2013;304(9):E951-63. Epub 2013/03/14. doi: 10.1152/ajpendo.00514.2012. PubMed PMID: 23482447; PMCID: PMC3651645.
https://www.ncbi.nlm.nih.gov/pubmed/23482447

Jung DY, Ko HJ, Lichtman EI, Lee E, Lawton E, Ong H, Yu K, Azuma Y, Friedline RH, Lee KW, Kim JK. Short-term weight loss attenuates local tissue inflammation and improves insulin sensitivity without affecting adipose inflammation in obese mice. Am J Physiol Endocrinol Metab. 2013;304(9):E964-76. Epub 2013/03/14. doi: 10.1152/ajpendo.00462.2012. PubMed PMID: 23482446; PMCID: PMC3651644.
https://www.ncbi.nlm.nih.gov/pubmed/23482446

Eren E, Parkin J, Adelanwa A, Cheneke B, Movileanu L, Khalid S, van den Berg B. Toward understanding the outer membrane uptake of small molecules by Pseudomonas aeruginosa. J Biol Chem. 2013;288(17):12042-53. Epub 2013/03/08. doi: 10.1074/jbc.M113.463570. PubMed PMID: 23467408; PMCID: PMC3636890. https://www.ncbi.nlm.nih.gov/pubmed/23467408 

D'Ambrogio A, Nagaoka K, Richter JD. Translational control of cell growth and malignancy by the CPEBs. Nat Rev Cancer. 2013;13(4):283-90. Epub 2013/03/01. doi: 10.1038/nrc3485. PubMed PMID: 23446545.
https://www.ncbi.nlm.nih.gov/pubmed/23446545

Czech MP, Tencerova M, Pedersen DJ, Aouadi M. Insulin signalling mechanisms for triacylglycerol storage. Diabetologia. 2013;56(5):949-64. Epub 2013/02/28. doi: 10.1007/s00125-013-2869-1. PubMed PMID: 23443243; PMCID: PMC3652374. https://www.ncbi.nlm.nih.gov/pubmed/23443243 

Kim S, Ishidate T, Sharma R, Soto MC, Conte D, Jr., Mello CC, Shirayama M. Wnt and CDK-1 regulate cortical release of WRM-1/beta-catenin to control cell division orientation in early Caenorhabditis elegans embryos. Proc Natl Acad Sci U S A. 2013;110(10):E918-27. Epub 2013/02/23. doi: 10.1073/pnas.1300769110. PubMed PMID: 23431196; PMCID: PMC3593879.
https://www.ncbi.nlm.nih.gov/pubmed/23431196

Chen CT, Ettinger AW, Huttner WB, Doxsey SJ. Resurrecting remnants: the lives of post-mitotic midbodies. Trends Cell Biol. 2013;23(3):118-28. Epub 2012/12/19. doi: 10.1016/j.tcb.2012.10.012. PubMed PMID: 23245592; PMCID: PMC4196272. https://www.ncbi.nlm.nih.gov/pubmed/23245592

Roth Flach RJ, Matevossian A, Akie TE, Negrin KA, Paul MT, Czech MP. beta3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation. J Biol Chem. 2013;288(4):2882-92. Epub 2012/12/14. doi: 10.1074/jbc.M112.412346. PubMed PMID: 23235150; PMCID: PMC3554952.
https://www.ncbi.nlm.nih.gov/pubmed/23235150

Wang M, Amano SU, Flach RJ, Chawla A, Aouadi M, Czech MP. Identification of Map4k4 as a novel suppressor of skeletal muscle differentiation. Mol Cell Biol. 2013;33(4):678-87. Epub 2012/12/05. doi: 10.1128/MCB.00618-12. PubMed PMID: 23207904; PMCID: PMC3571342.
https://www.ncbi.nlm.nih.gov/pubmed/23207904

Nechama M, Lin CL, Richter JD. An unusual two-step control of CPEB destruction by Pin1. Mol Cell Biol. 2013;33(1):48-58. Epub 2012/10/24. doi: 10.1128/MCB.00904-12. PubMed PMID: 23090969; PMCID: PMC3536308.
https://www.ncbi.nlm.nih.gov/pubmed/23090969

O'Connell O, Repik A, Reeves JD, Gonzalez-Perez MP, Quitadamo B, Anton ED, Duenas-Decamp M, Peters P, Lin R, Zolla-Pazner S, Corti D, Wallace A, Wang S, Kong XP, Lu S, Clapham PR. Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism. J Virol. 2013;87(1):187-98. Epub 2012/10/12. doi: 10.1128/JVI.01834-12. PubMed PMID: 23055568; PMCID: PMC3536387.
https://www.ncbi.nlm.nih.gov/pubmed/23055568

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