Search Close Search
Search Close Search
Page Menu

Publications 2017

Malaby AW, Das S, Chakravarthy S, Irving TC, Bilsel O, Lambright DG. Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors. Structure. 2018;26(1):106-17 e6. Epub 2017/12/26. doi: 10.1016/j.str.2017.11.019. PubMed PMID: 29276036; PMCID: PMC5752578.
https://www.ncbi.nlm.nih.gov/pubmed/29276036 

Nyalwidhe JO, Gallagher GR, Glenn LM, Morris MA, Vangala P, Jurczyk A, Bortell R, Harlan DM, Wang JP, Nadler JL. Coxsackievirus-Induced Proteomic Alterations in Primary Human Islets Provide Insights for the Etiology of Diabetes. J Endocr Soc. 2017;1(10):1272-86. Epub 2017/12/22. doi: 10.1210/js.2017-00278. PubMed PMID: 29264452; PMCID: PMC5686651.
https://www.ncbi.nlm.nih.gov/pubmed/29264452 

Soltis AR, Kennedy NJ, Xin X, Zhou F, Ficarro SB, Yap YS, Matthews BJ, Lauffenburger DA, White FM, Marto JA, Davis RJ, Fraenkel E. Hepatic Dysfunction Caused by Consumption of a High-Fat Diet. Cell Rep. 2017;21(11):3317-28. Epub 2017/12/16. doi: 10.1016/j.celrep.2017.11.059. PubMed PMID: 29241556; PMCID: PMC5734865.
https://www.ncbi.nlm.nih.gov/pubmed/29241556 

Kim SP, Frey JL, Li Z, Kushwaha P, Zoch ML, Tomlinson RE, Da H, Aja S, Noh HL, Kim JK, Hussain MA, Thorek DLJ, Wolfgang MJ, Riddle RC. Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes. Proc Natl Acad Sci U S A. 2017;114(52):E11238-E47. Epub 2017/12/13. doi: 10.1073/pnas.1707876115. PubMed PMID: 29229807; PMCID: PMC5748171. https://www.ncbi.nlm.nih.gov/pubmed/29229807

Aslan N, Watkin LB, Gil A, Mishra R, Clark FG, Welsh RM, Ghersi D, Luzuriaga K, Selin LK. Severity of Acute Infectious Mononucleosis Correlates with Cross-Reactive Influenza CD8 T-Cell Receptor Repertoires. MBio. 2017;8(6). Epub 2017/12/07. doi: 10.1128/mBio.01841-17. PubMed PMID: 29208744; PMCID: PMC5717389. https://www.ncbi.nlm.nih.gov/pubmed/29208744

Venkatesan AM, Vyas R, Gramann AK, Dresser K, Gujja S, Bhatnagar S, Chhangawala S, Gomes CBF, Xi HS, Lian CG, Houvras Y, Edwards YJK, Deng A, Green M, Ceol CJ. Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. J Clin Invest. 2018;128(1):294-308. Epub 2017/12/05. doi: 10.1172/JCI92513. PubMed PMID: 29202482; PMCID: PMC5749509. https://www.ncbi.nlm.nih.gov/pubmed/29202482

Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM. Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. MBio. 2017;8(6). Epub 2017/12/01. doi: 10.1128/mBio.01872-17. PubMed PMID: 29184017; PMCID: PMC5705919. https://www.ncbi.nlm.nih.gov/pubmed/29184017

Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis. Cell Metab. 2018;27(1):195-209 e6. Epub 2017/11/21. doi: 10.1016/j.cmet.2017.10.008. PubMed PMID: 29153407; PMCID: PMC5762420.
https://www.ncbi.nlm.nih.gov/pubmed/29153407 

Gao FB, Richter JD, Cleveland DW. Rethinking Unconventional Translation in Neurodegeneration. Cell. 2017;171(5):994-1000. Epub 2017/11/18. doi: 10.1016/j.cell.2017.10.042. PubMed PMID: 29149615; PMCID: PMC5728172.
https://www.ncbi.nlm.nih.gov/pubmed/29149615

Girnius N, Davis RJ. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017;21(7):1910-21. Epub 2017/11/16. doi: 10.1016/j.celrep.2017.10.067. PubMed PMID: 29141222; PMCID: PMC5711519.
https://www.ncbi.nlm.nih.gov/pubmed/29141222

Czech MP. Macrophages dispose of catecholamines in adipose tissue. Nat Med. 2017;23(11):1255-7. Epub 2017/11/09. doi: 10.1038/nm.4440. PubMed PMID: 29117176. https://www.ncbi.nlm.nih.gov/pubmed/29117176

Jourdan T, Nicoloro SM, Zhou Z, Shen Y, Liu J, Coffey NJ, Cinar R, Godlewski G, Gao B, Aouadi M, Czech MP, Kunos G. Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice. Mol Metab. 2017;6(11):1517-28. Epub 2017/11/07. doi: 10.1016/j.molmet.2017.08.011. PubMed PMID: 29107297; PMCID: PMC5681272.
https://www.ncbi.nlm.nih.gov/pubmed/29107297 

Bozler J, Kacsoh BZ, Chen H, Theurkauf WE, Weng Z, Bosco G. A systems level approach to temporal expression dynamics in Drosophila reveals clusters of long term memory genes. PLoS Genet. 2017;13(10):e1007054. Epub 2017/10/31. doi: 10.1371/journal.pgen.1007054. PubMed PMID: 29084214; PMCID: PMC5679645. https://www.ncbi.nlm.nih.gov/pubmed/29084214 

Kasheta M, Painter CA, Moore FE, Lobbardi R, Bryll A, Freiman E, Stachura D, Rogers AB, Houvras Y, Langenau DM, Ceol CJ. Identification and characterization of T reg-like cells in zebrafish. J Exp Med. 2017;214(12):3519-30. Epub 2017/10/27. doi: 10.1084/jem.20162084. PubMed PMID: 29066577; PMCID: PMC5716030. https://www.ncbi.nlm.nih.gov/pubmed/29066577 

Borel F, Tang Q, Gernoux G, Greer C, Wang Z, Barzel A, Kay MA, Shultz LD, Greiner DL, Flotte TR, Brehm MA, Mueller C. Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of alpha-1 Antitrypsin Deficiency. Mol Ther. 2017;25(11):2477-89. Epub 2017/10/17. doi: 10.1016/j.ymthe.2017.09.020. PubMed PMID: 29032169; PMCID: PMC5675605. https://www.ncbi.nlm.nih.gov/pubmed/29032169 

Hartwig C, Monis WJ, Chen X, Dickman DK, Pazour GJ, Faundez V. Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes. Dev Neurobiol. 2018;78(3):311-30. Epub 2017/10/08. doi: 10.1002/dneu.22542. PubMed PMID: 28986965; PMCID: PMC5816705. https://www.ncbi.nlm.nih.gov/pubmed/28986965

Zhang Y, Liu H, Li W, Zhang Z, Shang X, Zhang D, Li Y, Zhang S, Liu J, Hess RA, Pazour GJ, Zhang Z. Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice. Dev Biol. 2017;432(1):125-39. Epub 2017/10/02. doi: 10.1016/j.ydbio.2017.09.023. PubMed PMID: 28964737; PMCID: PMC5694392.
https://www.ncbi.nlm.nih.gov/pubmed/28964737 

Neiswender JV, Kortum RL, Bourque C, Kasheta M, Zon LI, Morrison DK, Ceol CJ. KIT Suppresses BRAF(V600E)-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling. Cancer Res. 2017;77(21):5820-30. Epub 2017/09/28. doi: 10.1158/0008-5472.CAN-17-0473. PubMed PMID: 28947418; PMCID: PMC5679278. https://www.ncbi.nlm.nih.gov/pubmed/28947418

Moraes MN, de Assis LVM, Henriques FDS, Batista ML, Jr., Guler AD, Castrucci AML. Cold-sensing TRPM8 channel participates in circadian control of the brown adipose tissue. Biochim Biophys Acta Mol Cell Res. 2017;1864(12):2415-27. Epub 2017/09/26. doi: 10.1016/j.bbamcr.2017.09.011. PubMed PMID: 28943398. https://www.ncbi.nlm.nih.gov/pubmed/28943398

Cotton JL, Li Q, Ma L, Park JS, Wang J, Ou J, Zhu LJ, Ip YT, Johnson RL, Mao J. YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme. Dev Cell. 2017;43(1):35-47 e4. Epub 2017/09/26. doi: 10.1016/j.devcel.2017.08.019. PubMed PMID: 28943241; PMCID: PMC5823011. https://www.ncbi.nlm.nih.gov/pubmed/28943241 

Kant S, Standen CL, Morel C, Jung DY, Kim JK, Swat W, Flavell RA, Davis RJ. A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress. Cell Rep. 2017;20(12):2775-83. Epub 2017/09/21. doi: 10.1016/j.celrep.2017.08.025. PubMed PMID: 28930674; PMCID: PMC5659285. https://www.ncbi.nlm.nih.gov/pubmed/28930674

Parhad SS, Tu S, Weng Z, Theurkauf WE. Adaptive Evolution Leads to Cross-Species Incompatibility in the piRNA Transposon Silencing Machinery. Dev Cell. 2017;43(1):60-70 e5. Epub 2017/09/19. doi: 10.1016/j.devcel.2017.08.012. PubMed PMID: 28919205; PMCID: PMC5653967.
https://www.ncbi.nlm.nih.gov/pubmed/28919205

Wu S, Fagan RR, Uttamapinant C, Lifshitz LM, Fogarty KE, Ting AY, Melikian HE. The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach. J Neurosci. 2017;37(39):9438-52. Epub 2017/08/30. doi: 10.1523/JNEUROSCI.3885-16.2017. PubMed PMID: 28847807; PMCID: PMC5618262. https://www.ncbi.nlm.nih.gov/pubmed/28847807

Shi X, Garcia G, 3rd, Van De Weghe JC, McGorty R, Pazour GJ, Doherty D, Huang B, Reiter JF. Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome. Nat Cell Biol. 2017;19(10):1178-88. Epub 2017/08/29. doi: 10.1038/ncb3599. PubMed PMID: 28846093; PMCID: PMC5695680.
https://www.ncbi.nlm.nih.gov/pubmed/28846093 

Harrington LB, Doxzen KW, Ma E, Liu JJ, Knott GJ, Edraki A, Garcia B, Amrani N, Chen JS, Cofsky JC, Kranzusch PJ, Sontheimer EJ, Davidson AR, Maxwell KL, Doudna JA. A Broad-Spectrum Inhibitor of CRISPR-Cas9. Cell. 2017;170(6):1224-33 e15. Epub 2017/08/29. doi: 10.1016/j.cell.2017.07.037. PubMed PMID: 28844692; PMCID: PMC5875921.
https://www.ncbi.nlm.nih.gov/pubmed/28844692 

Gioacchini N, Peterson CL. Chromatin remodeling: a complex affair. EMBO Rep. 2017;18(10):1673-4. Epub 2017/08/25. doi: 10.15252/embr.201744852. PubMed PMID: 28835548; PMCID: PMC5623829.
https://www.ncbi.nlm.nih.gov/pubmed/28835548 

Fitzgibbons TP, Edwards YJK, Shaw P, Iskandar A, Ahmed M, Bote J, Shah T, Sinha S, Gerszten RE, Keaney JF, Jr., Zile MR, Aurigemma GP. Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy. Front Cardiovasc Med. 2017;4:49. Epub 2017/08/22. doi: 10.3389/fcvm.2017.00049. PubMed PMID: 28824923; PMCID: PMC5541033.
https://www.ncbi.nlm.nih.gov/pubmed/28824923 

Xu P, Davis RJ. Correction for Xu and Davis, "c-Jun NH2-Terminal Kinase Is Required for Lineage-Specific Differentiation but Not Stem Cell Self-Renewal". Mol Cell Biol. 2017;37(17). Epub 2017/08/13. doi: 10.1128/MCB.00280-17. PubMed PMID: 28801454; PMCID: PMC5559671.
https://www.ncbi.nlm.nih.gov/pubmed/28801454 

Nechama M, Lin CL, Richter JD. Correction for Nechama et al., "An Unusual Two-Step Control of CPEB Destruction by Pin1". Mol Cell Biol. 2017;37(17). Epub 2017/08/13. doi: 10.1128/MCB.00220-17. PubMed PMID: 28801452; PMCID: PMC5559675. https://www.ncbi.nlm.nih.gov/pubmed/28801452 

Mori A, Holdorf AD, Walhout AJM. Many transcription factors contribute to C. elegans growth and fat storage. Genes Cells. 2017;22(9):770-84. Epub 2017/08/10. doi: 10.1111/gtc.12516. PubMed PMID: 28791781; PMCID: PMC6495572. https://www.ncbi.nlm.nih.gov/pubmed/28791781

Noon JB, Aroian RV. Recombinant subunit vaccines for soil-transmitted helminths. Parasitology. 2017;144(14):1845-70. Epub 2017/08/05. doi: 10.1017/S003118201700138X. PubMed PMID: 28770689; PMCID: PMC5729844. https://www.ncbi.nlm.nih.gov/pubmed/28770689

Falanga YT, Frascoli M, Kaymaz Y, Forconi C, Ong'echa JM, Bailey JA, Berg LJ, Moormann AM. High pathogen burden in childhood promotes the development of unconventional innate-like CD8+ T cells. JCI Insight. 2017;2(15). Epub 2017/08/05. doi: 10.1172/jci.insight.93814. PubMed PMID: 28768916; PMCID: PMC5543908. https://www.ncbi.nlm.nih.gov/pubmed/28768916

Gonzalez-Perez MP, Peters PJ, O'Connell O, Silva N, Harbison C, Cummings Macri S, Kaliyaperumal S, Luzuriaga K, Clapham PR. Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications. J Virol. 2017;91(20). Epub 2017/08/05. doi: 10.1128/JVI.00755-17. PubMed PMID: 28768859; PMCID: PMC5625501.
https://www.ncbi.nlm.nih.gov/pubmed/28768859 

Chen Z, Wang GX, Ma SL, Jung DY, Ha H, Altamimi T, Zhao XY, Guo L, Zhang P, Hu CR, Cheng JX, Lopaschuk GD, Kim JK, Lin JD. Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders. Mol Metab. 2017;6(8):863-72. Epub 2017/07/29. doi: 10.1016/j.molmet.2017.03.016. PubMed PMID: 28752050; PMCID: PMC5518721. https://www.ncbi.nlm.nih.gov/pubmed/28752050

Guilherme A, Pedersen DJ, Henchey E, Henriques FS, Danai LV, Shen Y, Yenilmez B, Jung D, Kim JK, Lodhi IJ, Semenkovich CF, Czech MP. Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming. Mol Metab. 2017;6(8):781-96. Epub 2017/07/29. doi: 10.1016/j.molmet.2017.05.012. PubMed PMID: 28752043; PMCID: PMC5518709. https://www.ncbi.nlm.nih.gov/pubmed/28752043

Leonard JL, Leonard DM, Wolfe SA, Liu J, Rivera J, Yang M, Leonard RT, Johnson JPS, Kumar P, Liebmann KL, Tutto AA, Mou Z, Simin KJ. The Dkk3 gene encodes a vital intracellular regulator of cell proliferation. PLoS One. 2017;12(7):e0181724. Epub 2017/07/25. doi: 10.1371/journal.pone.0181724. PubMed PMID: 28738084; PMCID: PMC5524345.
https://www.ncbi.nlm.nih.gov/pubmed/28738084 

Xue Y, Pradhan SK, Sun F, Chronis C, Tran N, Su T, Van C, Vashisht A, Wohlschlegel J, Peterson CL, Timmers HTM, Kurdistani SK, Carey MF. Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals. Mol Cell. 2017;67(4):594-607 e4. Epub 2017/07/25. doi: 10.1016/j.molcel.2017.06.029. PubMed PMID: 28735899; PMCID: PMC5573681. https://www.ncbi.nlm.nih.gov/pubmed/28735899

McFleder RL, Mansur F, Richter JD. Dynamic Control of Dendritic mRNA Expression by CNOT7 Regulates Synaptic Efficacy and Higher Cognitive Function. Cell Rep. 2017;20(3):683-96. Epub 2017/07/21. doi: 10.1016/j.celrep.2017.06.078. PubMed PMID: 28723570; PMCID: PMC5557029. https://www.ncbi.nlm.nih.gov/pubmed/28723570

Huang L, Pan D, Chen Q, Zhu LJ, Ou J, Wabitsch M, Wang YX. Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation. Nat Commun. 2017;8(1):68. Epub 2017/07/14. doi: 10.1038/s41467-017-00098-2. PubMed PMID: 28701693; PMCID: PMC5507986. https://www.ncbi.nlm.nih.gov/pubmed/28701693

Czech MP. Insulin action and resistance in obesity and type 2 diabetes. Nat Med. 2017;23(7):804-14. Epub 2017/07/12. doi: 10.1038/nm.4350. PubMed PMID: 28697184; PMCID: PMC6048953.
https://www.ncbi.nlm.nih.gov/pubmed/28697184 

Saddic LA, Nicoloro SM, Gupta OT, Czech MP, Gorham J, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Fitzgibbons TP, Muehlschlegel JD. Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia. Cardiovasc Diabetol. 2017;16(1):87. Epub 2017/07/09. doi: 10.1186/s12933-017-0567-x. PubMed PMID: 28687077; PMCID: PMC5501278. https://www.ncbi.nlm.nih.gov/pubmed/28687077

Martinez-Sanchez N, Seoane-Collazo P, Contreras C, Varela L, Villarroya J, Rial-Pensado E, Buque X, Aurrekoetxea I, Delgado TC, Vazquez-Martinez R, Gonzalez-Garcia I, Roa J, Whittle AJ, Gomez-Santos B, Velagapudi V, Tung YCL, Morgan DA, Voshol PJ, Martinez de Morentin PB, Lopez-Gonzalez T, Linares-Pose L, Gonzalez F, Chatterjee K, Sobrino T, Medina-Gomez G, Davis RJ, Casals N, Oresic M, Coll AP, Vidal-Puig A, Mittag J, Tena-Sempere M, Malagon MM, Dieguez C, Martinez-Chantar ML, Aspichueta P, Rahmouni K, Nogueiras R, Sabio G, Villarroya F, Lopez M. Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance. Cell Metab. 2017;26(1):212-29 e12. Epub 2017/07/07. doi: 10.1016/j.cmet.2017.06.014. PubMed PMID: 28683288; PMCID: PMC5501726.
https://www.ncbi.nlm.nih.gov/pubmed/28683288 

Wang J, Kho DH, Zhou JY, Davis RJ, Wu GS. MKP-1 suppresses PARP-1 degradation to mediate cisplatin resistance. Oncogene. 2017;36(43):5939-47. Epub 2017/06/27. doi: 10.1038/onc.2017.197. PubMed PMID: 28650468; PMCID: PMC5658239. https://www.ncbi.nlm.nih.gov/pubmed/28650468

Neto A, Ceol CJ. Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling. Pigment Cell Melanoma Res. 2018;31(1):115-9. Epub 2017/06/25. doi: 10.1111/pcmr.12610. PubMed PMID: 28646617.
https://www.ncbi.nlm.nih.gov/pubmed/28646617 

Sun X, Bizhanova A, Matheson TD, Yu J, Zhu LJ, Kaufman PD. Ki-67 Contributes to Normal Cell Cycle Progression and Inactive X Heterochromatin in p21 Checkpoint-Proficient Human Cells. Mol Cell Biol. 2017;37(17). Epub 2017/06/21. doi: 10.1128/MCB.00569-16. PubMed PMID: 28630280; PMCID: PMC5559680. https://www.ncbi.nlm.nih.gov/pubmed/28630280

Mou H, Smith JL, Peng L, Yin H, Moore J, Zhang XO, Song CQ, Sheel A, Wu Q, Ozata DM, Li Y, Anderson DG, Emerson CP, Sontheimer EJ, Moore MJ, Weng Z, Xue W. CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion. Genome Biol. 2017;18(1):108. Epub 2017/06/16. doi: 10.1186/s13059-017-1237-8. PubMed PMID: 28615073; PMCID: PMC5470253. https://www.ncbi.nlm.nih.gov/pubmed/28615073

Roth Flach RJ, DiStefano MT, Danai LV, Senol-Cosar O, Yawe JC, Kelly M, Garcia Menendez L, Czech MP. Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity. Am J Physiol Endocrinol Metab. 2017;313(3):E303-E13. Epub 2017/06/15. doi: 10.1152/ajpendo.00037.2017. PubMed PMID: 28611026; PMCID: PMC5625083.
https://www.ncbi.nlm.nih.gov/pubmed/28611026 

Roberts FR, Hupple C, Norowski E, Walsh NC, Przewozniak N, Aryee KE, Van Dessel FM, Jurczyk A, Harlan DM, Greiner DL, Bortell R, Yang C. Possible type 1 diabetes risk prediction: Using ultrasound imaging to assess pancreas inflammation in the inducible autoimmune diabetes BBDR model. PLoS One. 2017;12(6):e0178641. Epub 2017/06/13. doi: 10.1371/journal.pone.0178641. PubMed PMID: 28605395; PMCID: PMC5468055.
https://www.ncbi.nlm.nih.gov/pubmed/28605395 

Hu Q, D'Amora DR, MacNeil LT, Walhout AJM, Kubiseski TJ. The Oxidative Stress Response in Caenorhabditis elegans Requires the GATA Transcription Factor ELT-3 and SKN-1/Nrf2. Genetics. 2017;206(4):1909-22. Epub 2017/06/11. doi: 10.1534/genetics.116.198788. PubMed PMID: 28600327; PMCID: PMC5560797. https://www.ncbi.nlm.nih.gov/pubmed/28600327

Haraszti RA, Roux L, Coles AH, Turanov AA, Alterman JF, Echeverria D, Godinho B, Aronin N, Khvorova A. 5-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo. Nucleic Acids Res. 2017;45(13):7581-92. Epub 2017/06/08. doi: 10.1093/nar/gkx507. PubMed PMID: 28591791; PMCID: PMC5570069. https://www.ncbi.nlm.nih.gov/pubmed/28591791

Mirza Z, Soto ER, Dikengil F, Levitz SM, Ostroff GR. Beta-Glucan Particles as Vaccine Adjuvant Carriers. Methods Mol Biol. 2017;1625:143-57. Epub 2017/06/07. doi: 10.1007/978-1-4939-7104-6_11. PubMed PMID: 28584989.
https://www.ncbi.nlm.nih.gov/pubmed/28584989 

Monis WJ, Faundez V, Pazour GJ. BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia. J Cell Biol. 2017;216(7):2131-50. Epub 2017/06/04. doi: 10.1083/jcb.201611138. PubMed PMID: 28576874; PMCID: PMC5496619.
https://www.ncbi.nlm.nih.gov/pubmed/28576874 

Xu R, Zhang C, Shin DY, Kim JM, Lalani S, Li N, Yang YS, Liu Y, Eiseman M, Davis RJ, Shim JH, Greenblatt MB. c-Jun N-Terminal Kinases (JNKs) Are Critical Mediators of Osteoblast Activity In Vivo. J Bone Miner Res. 2017;32(9):1811-5. Epub 2017/06/01. doi: 10.1002/jbmr.3184. PubMed PMID: 28561373; PMCID: PMC5599178. https://www.ncbi.nlm.nih.gov/pubmed/28561373

Zheng K, Lu P, Delpapa E, Bellve K, Deng R, Condon JC, Fogarty K, Lifshitz LM, Simas TAM, Shi F, ZhuGe R. Bitter taste receptors as targets for tocolytics in preterm labor therapy. FASEB J. 2017;31(9):4037-52. Epub 2017/06/01. doi: 10.1096/fj.201601323RR. PubMed PMID: 28559440; PMCID: PMC5572693.
https://www.ncbi.nlm.nih.gov/pubmed/28559440

Suk S, Kwon GT, Lee E, Jang WJ, Yang H, Kim JH, Thimmegowda NR, Chung MY, Kwon JY, Yang S, Kim JK, Park JHY, Lee KW. Gingerenone A, a polyphenol present in ginger, suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice. Mol Nutr Food Res. 2017;61(10). Epub 2017/05/31. doi: 10.1002/mnfr.201700139. PubMed PMID: 28556482; PMCID: PMC5947313.
https://www.ncbi.nlm.nih.gov/pubmed/28556482 

Clapier CR, Iwasa J, Cairns BR, Peterson CL. Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes. Nat Rev Mol Cell Biol. 2017;18(7):407-22. Epub 2017/05/18. doi: 10.1038/nrm.2017.26. PubMed PMID: 28512350.
https://www.ncbi.nlm.nih.gov/pubmed/28512350 

Tammela T, Sanchez-Rivera FJ, Cetinbas NM, Wu K, Joshi NS, Helenius K, Park Y, Azimi R, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz OH, Xue W, Katajisto P, Bhutkar A, Jacks T. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. 2017;545(7654):355-9. Epub 2017/05/11. doi: 10.1038/nature22334. PubMed PMID: 28489818; PMCID: PMC5903678.
https://www.ncbi.nlm.nih.gov/pubmed/28489818 

Kaymaz Y, Oduor CI, Yu H, Otieno JA, Ong'echa JM, Moormann AM, Bailey JA. Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type-Specific Differences. Mol Cancer Res. 2017;15(5):563-76. Epub 2017/05/04. doi: 10.1158/1541-7786.MCR-16-0305. PubMed PMID: 28465297; PMCID: PMC5471630.
https://www.ncbi.nlm.nih.gov/pubmed/28465297 

Lin Z, Neiswender J, Fang B, Ma X, Zhang J, Hu X. Value of circulating cell-free DNA analysis as a diagnostic tool for breast cancer: a meta-analysis. Oncotarget. 2017;8(16):26625-36. Epub 2017/05/04. doi: 10.18632/oncotarget.15775. PubMed PMID: 28460452; PMCID: PMC5432284.
https://www.ncbi.nlm.nih.gov/pubmed/28460452 

Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J. INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma. Oncogene. 2017;36(35):4997-5005. Epub 2017/05/02. doi: 10.1038/onc.2017.117. PubMed PMID: 28459465; PMCID: PMC5578876.
https://www.ncbi.nlm.nih.gov/pubmed/28459465 

Kouno T, Silvas TV, Hilbert BJ, Shandilya SMD, Bohn MF, Kelch BA, Royer WE, Somasundaran M, Kurt Yilmaz N, Matsuo H, Schiffer CA. Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity. Nat Commun. 2017;8:15024. Epub 2017/04/30. doi: 10.1038/ncomms15024. PubMed PMID: 28452355; PMCID: PMC5414352.
https://www.ncbi.nlm.nih.gov/pubmed/28452355 

Miller JRC, Pfister EL, Liu W, Andre R, Trager U, Kennington LA, Lo K, Dijkstra S, Macdonald D, Ostroff G, Aronin N, Tabrizi SJ. Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells. Sci Rep. 2017;7:46740. Epub 2017/04/25. doi: 10.1038/srep46740. PubMed PMID: 28436437; PMCID: PMC5402279. https://www.ncbi.nlm.nih.gov/pubmed/28436437

Liu H, Li W, Zhang Y, Zhang Z, Shang X, Zhang L, Zhang S, Li Y, Somoza AV, Delpi B, Gerton GL, Foster JA, Hess RA, Pazour GJ, Zhang Z. IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation. Biol Reprod. 2017;96(5):993-1006. Epub 2017/04/22. doi: 10.1093/biolre/iox029. PubMed PMID: 28430876; PMCID: PMC6355109. https://www.ncbi.nlm.nih.gov/pubmed/28430876

Quattrochi B, Gulvady A, Driscoll DR, Sano M, Klimstra DS, Turner CE, Lewis BC. MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression. Oncotarget. 2017;8(22):35902-18. Epub 2017/04/19. doi: 10.18632/oncotarget.16277. PubMed PMID: 28415794; PMCID: PMC5482626. https://www.ncbi.nlm.nih.gov/pubmed/28415794

Rasoulianboroujeni M, Kupgan G, Moghadam F, Tahriri M, Boughdachi A, Khoshkenar P, Ambrose JJ, Kiaie N, Vashaee D, Ramsey JD, Tayebi L. Development of a DNA-liposome complex for gene delivery applications. Mater Sci Eng C Mater Biol Appl. 2017;75:191-7. Epub 2017/04/19. doi: 10.1016/j.msec.2017.02.012. PubMed PMID: 28415454.
https://www.ncbi.nlm.nih.gov/pubmed/28415454

Pearring JN, San Agustin JT, Lobanova ES, Gabriel CJ, Lieu EC, Monis WJ, Stuck MW, Strittmatter L, Jaber SM, Arshavsky VY, Pazour GJ. Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration. PLoS Genet. 2017;13(4):e1006740. Epub 2017/04/15. doi: 10.1371/journal.pgen.1006740. PubMed PMID: 28410364; PMCID: PMC5409180. https://www.ncbi.nlm.nih.gov/pubmed/28410364

Oduor CI, Movassagh M, Kaymaz Y, Chelimo K, Otieno J, Ong'echa JM, Moormann AM, Bailey JA. Human and Epstein-Barr Virus miRNA Profiling as Predictive Biomarkers for Endemic Burkitt Lymphoma. Front Microbiol. 2017;8:501. Epub 2017/04/13. doi: 10.3389/fmicb.2017.00501. PubMed PMID: 28400759; PMCID: PMC5368269.
https://www.ncbi.nlm.nih.gov/pubmed/28400759 

Shin J, Paek KY, Ivshina M, Stackpole EE, Richter JD. Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism. Nucleic Acids Res. 2017;45(11):6793-804. Epub 2017/04/07. doi: 10.1093/nar/gkx239. PubMed PMID: 28383716; PMCID: PMC5499868. https://www.ncbi.nlm.nih.gov/pubmed/28383716

Colleoni B, Paternot S, Pita JM, Bisteau X, Coulonval K, Davis RJ, Raspe E, Roger PP. JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21. Oncogene. 2017;36(30):4349-61. Epub 2017/04/04. doi: 10.1038/onc.2017.7. PubMed PMID: 28368408; PMCID: PMC5537611.
https://www.ncbi.nlm.nih.gov/pubmed/28368408 

Keeler AM, Liu D, Zieger M, Xiong L, Salemi J, Bellve K, Byrne BJ, Fuller DD, ZhuGe R, ElMallah MK. Airway smooth muscle dysfunction in Pompe (Gaa(-/-) ) mice. Am J Physiol Lung Cell Mol Physiol. 2017;312(6):L873-L81. Epub 2017/03/25. doi: 10.1152/ajplung.00568.2016. PubMed PMID: 28336814; PMCID: PMC5495946. https://www.ncbi.nlm.nih.gov/pubmed/28336814

Azmi IF, Watanabe S, Maloney MF, Kang S, Belsky JA, MacAlpine DM, Peterson CL, Bell SP. Nucleosomes influence multiple steps during replication initiation. Elife. 2017;6. Epub 2017/03/23. doi: 10.7554/eLife.22512. PubMed PMID: 28322723; PMCID: PMC5400510.
https://www.ncbi.nlm.nih.gov/pubmed/28322723 

Mou H, Moore J, Malonia SK, Li Y, Ozata DM, Hough S, Song CQ, Smith JL, Fischer A, Weng Z, Green MR, Xue W. Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis. Proc Natl Acad Sci U S A. 2017;114(14):3648-53. Epub 2017/03/23. doi: 10.1073/pnas.1620861114. PubMed PMID: 28320962; PMCID: PMC5389295.
https://www.ncbi.nlm.nih.gov/pubmed/28320962 

Doloff JC, Veiseh O, Vegas AJ, Tam HH, Farah S, Ma M, Li J, Bader A, Chiu A, Sadraei A, Aresta-Dasilva S, Griffin M, Jhunjhunwala S, Webber M, Siebert S, Tang K, Chen M, Langan E, Dholokia N, Thakrar R, Qi M, Oberholzer J, Greiner DL, Langer R, Anderson DG. Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. Nat Mater. 2017;16(6):671-80. Epub 2017/03/21. doi: 10.1038/nmat4866. PubMed PMID: 28319612; PMCID: PMC5445003.
https://www.ncbi.nlm.nih.gov/pubmed/28319612 

Chao LF, Singh M, Thompson J, Yates JR, 3rd, Hagstrom KA. An SMC-like protein binds and regulates Caenorhabditis elegans condensins. PLoS Genet. 2017;13(3):e1006614. Epub 2017/03/17. doi: 10.1371/journal.pgen.1006614. PubMed PMID: 28301465; PMCID: PMC5373644.
https://www.ncbi.nlm.nih.gov/pubmed/28301465

Bruel AL, Franco B, Duffourd Y, Thevenon J, Jego L, Lopez E, Deleuze JF, Doummar D, Giles RH, Johnson CA, Huynen MA, Chevrier V, Burglen L, Morleo M, Desguerres I, Pierquin G, Doray B, Gilbert-Dussardier B, Reversade B, Steichen-Gersdorf E, Baumann C, Panigrahi I, Fargeot-Espaliat A, Dieux A, David A, Goldenberg A, Bongers E, Gaillard D, Argente J, Aral B, Gigot N, St-Onge J, Birnbaum D, Phadke SR, Cormier-Daire V, Eguether T, Pazour GJ, Herranz-Perez V, Goldstein JS, Pasquier L, Loget P, Saunier S, Megarbane A, Rosnet O, Leroux MR, Wallingford JB, Blacque OE, Nachury MV, Attie-Bitach T, Riviere JB, Faivre L, Thauvin-Robinet C. Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes. J Med Genet. 2017;54(6):371-80. Epub 2017/03/16. doi: 10.1136/jmedgenet-2016-104436. PubMed PMID: 28289185; PMCID: PMC5557276. https://www.ncbi.nlm.nih.gov/pubmed/28289185

McJunkin K, Ambros V. A microRNA family exerts maternal control on sex determination in C. elegans. Genes Dev. 2017;31(4):422-37. Epub 2017/03/11. doi: 10.1101/gad.290155.116. PubMed PMID: 28279983; PMCID: PMC5358761. https://www.ncbi.nlm.nih.gov/pubmed/28279983

Beauparlant D, Rusert P, Magnus C, Kadelka C, Weber J, Uhr T, Zagordi O, Oberle C, Duenas-Decamp MJ, Clapham PR, Metzner KJ, Gunthard HF, Trkola A. Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality. PLoS Pathog. 2017;13(3):e1006255. Epub 2017/03/07. doi: 10.1371/journal.ppat.1006255. PubMed PMID: 28264054; PMCID: PMC5354460. https://www.ncbi.nlm.nih.gov/pubmed/28264054

Khvorova A, Watts JK. The chemical evolution of oligonucleotide therapies of clinical utility. Nat Biotechnol. 2017;35(3):238-48. Epub 2017/03/01. doi: 10.1038/nbt.3765. PubMed PMID: 28244990; PMCID: PMC5517098.
https://www.ncbi.nlm.nih.gov/pubmed/28244990 

Lee PL, Jung SM, Guertin DA. The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond. Trends Endocrinol Metab. 2017;28(5):319-39. Epub 2017/02/27. doi: 10.1016/j.tem.2017.01.004. PubMed PMID: 28237819; PMCID: PMC5682923. https://www.ncbi.nlm.nih.gov/pubmed/28237819

Rainwater-Lovett K, Ziemniak C, Watson D, Luzuriaga K, Siberry G, Petru A, Chen Y, Uprety P, McManus M, Ho YC, Lamers SL, Persaud D. Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection. PLoS One. 2017;12(2):e0170548. Epub 2017/02/09. doi: 10.1371/journal.pone.0170548. PubMed PMID: 28178277; PMCID: PMC5298215 our adherence to PLOS ONE policies on sharing data and materials. https://www.ncbi.nlm.nih.gov/pubmed/28178277

Sherrard R, Luehr S, Holzkamp H, McJunkin K, Memar N, Conradt B. miRNAs cooperate in apoptosis regulation during C. elegans development. Genes Dev. 2017;31(2):209-22. Epub 2017/02/09. doi: 10.1101/gad.288555.116. PubMed PMID: 28167500; PMCID: PMC5322734. https://www.ncbi.nlm.nih.gov/pubmed/28167500

Henriques FS, Sertie RAL, Franco FO, Knobl P, Neves RX, Andreotti S, Lima FB, Guilherme A, Seelaender M, Batista ML, Jr. Early suppression of adipocyte lipid turnover induces immunometabolic modulation in cancer cachexia syndrome. FASEB J. 2017;31(5):1976-86. Epub 2017/02/01. doi: 10.1096/fj.201601151R. PubMed PMID: 28138038.
https://www.ncbi.nlm.nih.gov/pubmed/28138038 

Nishita M, Park SY, Nishio T, Kamizaki K, Wang Z, Tamada K, Takumi T, Hashimoto R, Otani H, Pazour GJ, Hsu VW, Minami Y. Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness. Sci Rep. 2017;7(1):1. Epub 2017/01/28. doi: 10.1038/s41598-016-0028-x. PubMed PMID: 28127051; PMCID: PMC5428335.
https://www.ncbi.nlm.nih.gov/pubmed/28127051 

Cederquist CT, Lentucci C, Martinez-Calejman C, Hayashi V, Orofino J, Guertin D, Fried SK, Lee MJ, Cardamone MD, Perissi V. Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Mol Metab. 2017;6(1):125-37. Epub 2017/01/27. doi: 10.1016/j.molmet.2016.10.007. PubMed PMID: 28123943; PMCID: PMC5220281. https://www.ncbi.nlm.nih.gov/pubmed/28123943

Gao FB, Richter JD. Microsatellite Expansion Diseases: Repeat Toxicity Found in Translation. Neuron. 2017;93(2):249-51. Epub 2017/01/20. doi: 10.1016/j.neuron.2017.01.001. PubMed PMID: 28103472.
https://www.ncbi.nlm.nih.gov/pubmed/28103472 

Yilmaz LS, Walhout AJ. Metabolic network modeling with model organisms. Curr Opin Chem Biol. 2017;36:32-9. Epub 2017/01/16. doi: 10.1016/j.cbpa.2016.12.025. PubMed PMID: 28088694; PMCID: PMC5458607.
https://www.ncbi.nlm.nih.gov/pubmed/28088694 

Jourdan T, Szanda G, Cinar R, Godlewski G, Holovac DJ, Park JK, Nicoloro S, Shen Y, Liu J, Rosenberg AZ, Liu Z, Czech MP, Kunos G. Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes. Diabetes. 2017;66(4):994-1007. Epub 2017/01/14. doi: 10.2337/db16-1199. PubMed PMID: 28082458; PMCID: PMC5360301.
https://www.ncbi.nlm.nih.gov/pubmed/28082458 

Lu P, Zhang CH, Lifshitz LM, ZhuGe R. Extraoral bitter taste receptors in health and disease. J Gen Physiol. 2017;149(2):181-97. Epub 2017/01/06. doi: 10.1085/jgp.201611637. PubMed PMID: 28053191; PMCID: PMC5299619.
https://www.ncbi.nlm.nih.gov/pubmed/28053191 

Secco B, Camire E, Briere MA, Caron A, Billong A, Gelinas Y, Lemay AM, Tharp KM, Lee PL, Gobeil S, Guimond JV, Patey N, Guertin DA, Stahl A, Haddad E, Marsolais D, Bosse Y, Birsoy K, Laplante M. Amplification of Adipogenic Commitment by VSTM2A. Cell Rep. 2017;18(1):93-106. Epub 2017/01/05. doi: 10.1016/j.celrep.2016.12.015. PubMed PMID: 28052263; PMCID: PMC5551894. https://www.ncbi.nlm.nih.gov/pubmed/28052263

Khvorova A. Oligonucleotide Therapeutics - A New Class of Cholesterol-Lowering Drugs. N Engl J Med. 2017;376(1):4-7. Epub 2017/01/05. doi: 10.1056/NEJMp1614154. PubMed PMID: 28052224.
https://www.ncbi.nlm.nih.gov/pubmed/28052224 

Maurizi G, Poloni A, Mattiucci D, Santi S, Maurizi A, Izzi V, Giuliani A, Mancini S, Zingaretti MC, Perugini J, Severi I, Falconi M, Vivarelli M, Rippo MR, Corvera S, Giordano A, Leoni P, Cinti S. Human White Adipocytes Convert Into "Rainbow" Adipocytes In Vitro. J Cell Physiol. 2017;232(10):2887-99. Epub 2016/12/18. doi: 10.1002/jcp.25743. PubMed PMID: 27987321.
https://www.ncbi.nlm.nih.gov/pubmed/27987321 

Ly S, Navaroli DM, Didiot MC, Cardia J, Pandarinathan L, Alterman JF, Fogarty K, Standley C, Lifshitz LM, Bellve KD, Prot M, Echeverria D, Corvera S, Khvorova A. Visualization of self-delivering hydrophobically modified siRNA cellular internalization. Nucleic Acids Res. 2017;45(1):15-25. Epub 2016/12/03. doi: 10.1093/nar/gkw1005. PubMed PMID: 27899655; PMCID: PMC5224471.
https://www.ncbi.nlm.nih.gov/pubmed/27899655 

Parsi KM, Hennessy E, Kearns N, Maehr R. Using an Inducible CRISPR-dCas9-KRAB Effector System to Dissect Transcriptional Regulation in Human Embryonic Stem Cells. Methods Mol Biol. 2017;1507:221-33. Epub 2016/11/11. doi: 10.1007/978-1-4939-6518-2_16. PubMed PMID: 27832543.
https://www.ncbi.nlm.nih.gov/pubmed/27832543 

Weiss ER, Alter G, Ogembo JG, Henderson JL, Tabak B, Bakis Y, Somasundaran M, Garber M, Selin L, Luzuriaga K. High Epstein-Barr Virus Load and Genomic Diversity Are Associated with Generation of gp350-Specific Neutralizing Antibodies following Acute Infectious Mononucleosis. J Virol. 2017;91(1). Epub 2016/11/01. doi: 10.1128/JVI.01562-16. PubMed PMID: 27733645; PMCID: PMC5165192. https://www.ncbi.nlm.nih.gov/pubmed/27733645