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Publications 2019

Allen TM, Brehm MA, Bridges S, Ferguson S, Kumar P, Mirochnitchenko O, Palucka K, Pelanda R, Sanders-Beer B, Shultz LD, Su L, PrabhuDas M. Humanized immune system mouse models: progress, challenges and opportunities. Nat Immunol. 2019;20(7):770-4. Epub 2019/06/05. doi: 10.1038/s41590-019-0416-z. PubMed PMID: 31160798.
https://www.ncbi.nlm.nih.gov/pubmed/31160798

Batista TM, Garcia-Martin R, Cai W, Konishi M, O'Neill BT, Sakaguchi M, Kim JH, Jung DY, Kim JK, Kahn CR. Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo. Cell Rep. 2019;26(12):3429-43 e3. Epub 2019/03/21. doi: 10.1016/j.celrep.2019.02.081. PubMed PMID: 30893613; PMCID: PMC6543850.
https://www.ncbi.nlm.nih.gov/pubmed/30893613

Biscans A, Coles A, Haraszti R, Echeverria D, Hassler M, Osborn M, Khvorova A. Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo. Nucleic Acids Res. 2019;47(3):1082-96. Epub 2018/12/14. doi: 10.1093/nar/gky1239. PubMed PMID: 30544191; PMCID: PMC6379722. https://www.ncbi.nlm.nih.gov/pubmed/30544191   

Blaszczak AM, Wright VP, Anandani K, Liu J, Jalilvand A, Bergin S, Nicoloro SM, Czech MP, Lafuse W, Deng T, Bradley D, Hsueh WA. Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism. J Immunol. 2019;202(8):2451-9. Epub 2019/03/10. doi: 10.4049/jimmunol.1801470. PubMed PMID: 30850480. https://www.ncbi.nlm.nih.gov/pubmed/30850480   

Boucher JI, Whitfield TW, Dauphin A, Nachum G, Hollins C, Zeldovich KB, Swanstrom R, Schiffer CA, Luban J, Bolon DNA. Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution. Mol Biol Evol. 2019;36(4):798-810. Epub 2019/02/06. doi: 10.1093/molbev/msz022. PubMed PMID: 30721995.
https://www.ncbi.nlm.nih.gov/pubmed/30721995   

Braun MC, Castillo-Ruiz A, Indic P, Jung DY, Kim JK, Brown RH, Jr., Swoap SJ, Schwartz WJ. Defective daily temperature regulation in a mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2019;311:305-12. Epub 2018/07/22. doi: 10.1016/j.expneurol.2018.07.008. PubMed PMID: 30031021; PMCID: PMC6263852.
https://www.ncbi.nlm.nih.gov/pubmed/30031021    

Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Mendez-Solis O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. TRIM5alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27(11):3269-83 e6. Epub 2019/06/13. doi: 10.1016/j.celrep.2019.05.040. PubMed PMID: 31189110. https://www.ncbi.nlm.nih.gov/pubmed/31189110   

Choi S, Ambros V. The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis. Development. 2019;146(5). Epub 2019/02/13. doi: 10.1242/dev.164293. PubMed PMID: 30745431; PMCID: PMC6432661.
https://www.ncbi.nlm.nih.gov/pubmed/30745431    

Chowdhury M, Li CF, He Z, Lu Y, Liu XS, Wang YF, Ip YT, Strand MR, Yu XQ. Toll family members bind multiple Spatzle proteins and activate antimicrobial peptide gene expression in Drosophila. J Biol Chem. 2019;294(26):10172-81. Epub 2019/05/16. doi: 10.1074/jbc.RA118.006804. PubMed PMID: 31088910.
https://www.ncbi.nlm.nih.gov/pubmed/31088910    

Dahan O, Dorfman BS, Sayin S, Rosener B, Hua T, Yarden A, Mitchell A. Harnessing robotic automation and web-based technologies to modernize scientific outreach. PLoS Biol. 2019;17(6):e3000348. Epub 2019/06/27. doi: 10.1371/journal.pbio.3000348. PubMed PMID: 31242174. https://www.ncbi.nlm.nih.gov/pubmed/31242174   

Duan J, Lambright DG. TRAPPing a Rab GTPase by the Tail. Dev Cell. 2019;48(1):9-11. Epub 2019/01/09. doi: 10.1016/j.devcel.2018.12.008. PubMed PMID: 30620905.
https://www.ncbi.nlm.nih.gov/pubmed/30620905    

Dumas SN, Guo CA, Kim JK, Friedline RH, Ntambi JM. Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver. Biochem Biophys Res Commun. 2019;508(1):87-91. Epub 2018/11/25. doi: 10.1016/j.bbrc.2018.11.083. PubMed PMID: 30470572; PMCID: PMC6309575. https://www.ncbi.nlm.nih.gov/pubmed/30470572   

Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Peterfy M. Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans. Obesity (Silver Spring). 2019;27(3):434-43. Epub 2019/02/26. doi: 10.1002/oby.22418. PubMed PMID: 30801985; PMCID: PMC6474357.
https://www.ncbi.nlm.nih.gov/pubmed/30801985    

Farah S, Doloff JC, Muller P, Sadraei A, Han HJ, Olafson K, Vyas K, Tam HH, Hollister-Lock J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, Oberholzer J, Weir GC, Greiner DL, Langer R, Anderson DG. Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations. Nat Mater. 2019. Epub 2019/06/27. doi: 10.1038/s41563-019-0377-5. PubMed PMID: 31235902.
https://www.ncbi.nlm.nih.gov/pubmed/31235902    

Feldman JL, Peterson CL. Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability. Cell Rep. 2019;27(10):2978-89 e5. Epub 2019/06/06. doi: 10.1016/j.celrep.2019.05.009. PubMed PMID: 31167142.
https://www.ncbi.nlm.nih.gov/pubmed/31167142    

Fernandez S, Viola JM, Torres A, Wallace M, Trefely S, Zhao S, Affronti HC, Gengatharan JM, Guertin DA, Snyder NW, Metallo CM, Wellen KE. Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. Cell Rep. 2019;27(9):2772-84 e6. Epub 2019/05/30. doi: 10.1016/j.celrep.2019.04.112. PubMed PMID: 31141698; PMCID: PMC6608748.
https://www.ncbi.nlm.nih.gov/pubmed/31141698    

Fischer DS, Fiedler AK, Kernfeld EM, Genga RMJ, Bastidas-Ponce A, Bakhti M, Lickert H, Hasenauer J, Maehr R, Theis FJ. Inferring population dynamics from single-cell RNA-sequencing time series data. Nat Biotechnol. 2019;37(4):461-8. Epub 2019/04/03. doi: 10.1038/s41587-019-0088-0. PubMed PMID: 30936567.
https://www.ncbi.nlm.nih.gov/pubmed/30936567    

Gawron MA, Duval M, Carbone C, Jaiswal S, Wallace A, Martin JC, 3rd, Dauphin A, Brehm MA, Greiner DL, Shultz LD, Luban J, Cavacini LA. Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1. J Immunol. 2019;202(3):799-804. Epub 2018/12/30. doi: 10.4049/jimmunol.1801085. PubMed PMID: 30593536; PMCID: PMC6344273.
https://www.ncbi.nlm.nih.gov/pubmed/30593536    

Genga RMJ, Kernfeld EM, Parsi KM, Parsons TJ, Ziller MJ, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 2019;27(3):708-18 e10. Epub 2019/04/18. doi: 10.1016/j.celrep.2019.03.076. PubMed PMID: 30995470; PMCID: PMC6525305.
https://www.ncbi.nlm.nih.gov/pubmed/30995470    

Ghadieh HE, Russo L, Muturi HT, Ghanem SS, Manaserh IH, Noh HL, Suk S, Kim JK, Hill JW, Najjar SM. Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis. Metabolism. 2019;93:33-43. Epub 2019/01/22. doi: 10.1016/j.metabol.2019.01.008. PubMed PMID: 30664851; PMCID: PMC6401268.
https://www.ncbi.nlm.nih.gov/pubmed/30664851    

Guilherme A, Henriques F, Bedard AH, Czech MP. Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus. Nat Rev Endocrinol. 2019;15(4):207-25. Epub 2019/02/09. doi: 10.1038/s41574-019-0165-y. PubMed PMID: 30733616. https://www.ncbi.nlm.nih.gov/pubmed/30733616   

Hamza Z, El-Hashash M, Aly S, Hathout A, Soto E, Sabry B, Ostroff G. Preparation and characterization of yeast cell wall beta-glucan encapsulated humic acid nanoparticles as an enhanced aflatoxin B1 binder. Carbohydr Polym. 2019;203:185-92. Epub 2018/10/16. doi: 10.1016/j.carbpol.2018.08.047. PubMed PMID: 30318202.
https://www.ncbi.nlm.nih.gov/pubmed/30318202    

Hayden CA, Hung CY, Zhang H, Negron A, Esquerra R, Ostroff G, Abraham A, Lopez AG, Gonzales JE, Howard JA. Maize-Produced Ag2 as a Subunit Vaccine for Valley Fever. J Infect Dis. 2019. Epub 2019/06/12. doi: 10.1093/infdis/jiz196. PubMed PMID: 31184702. https://www.ncbi.nlm.nih.gov/pubmed/31184702   

Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM. A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Rep. 2019;28(3):773-91 e7. Epub 2019/07/18. doi: 10.1016/j.celrep.2019.06.061. PubMed PMID: 31315054. https://www.ncbi.nlm.nih.gov/pubmed/31315054   

Ilbay O, Ambros V. Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans. Curr Biol. 2019;29(11):1735-45 e4. Epub 2019/05/21. doi: 10.1016/j.cub.2019.04.034. PubMed PMID: 31104929.
https://www.ncbi.nlm.nih.gov/pubmed/31104929    

Jangalwe S, Kapoor VN, Xu J, Girnius N, Kennedy NJ, Edwards YJK, Welsh RM, Davis RJ, Brehm MA. Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim. J Immunol. 2019;202(3):647-51. Epub 2019/01/06. doi: 10.4049/jimmunol.1800278. PubMed PMID: 30610162; PMCID: PMC6344249.
https://www.ncbi.nlm.nih.gov/pubmed/30610162    

Jung SM, Sanchez-Gurmaches J, Guertin DA. Brown Adipose Tissue Development and Metabolism. Handb Exp Pharmacol. 2019;251:3-36. Epub 2018/09/12. doi: 10.1007/164_2018_168. PubMed PMID: 30203328.
https://www.ncbi.nlm.nih.gov/pubmed/30203328    

Kucukural A, Yukselen O, Ozata DM, Moore MJ, Garber M. DEBrowser: interactive differential expression analysis and visualization tool for count data. BMC Genomics. 2019;20(1):6. Epub 2019/01/07. doi: 10.1186/s12864-018-5362-x. PubMed PMID: 30611200; PMCID: PMC6321710. https://www.ncbi.nlm.nih.gov/pubmed/30611200   

Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W. Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes. Hepatology. 2019. Epub 2019/06/13. doi: 10.1002/hep.30807. PubMed PMID: 31188495.
https://www.ncbi.nlm.nih.gov/pubmed/31188495    

Li Q, Nirala NK, Chen HJ, Nie Y, Wang W, Zhang B, Czech MP, Wang Q, Xu L, Mao J, Ip YT. The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium. J Cell Physiol. 2019. Epub 2019/05/02. doi: 10.1002/jcp.28756. PubMed PMID: 31042012. https://www.ncbi.nlm.nih.gov/pubmed/31042012   

Liu B, Molinaro G, Shu H, Stackpole EE, Huber KM, Richter JD. Optimization of ribosome profiling using low-input brain tissue from fragile X syndrome model mice. Nucleic Acids Res. 2019;47(5):e25. Epub 2018/12/28. doi: 10.1093/nar/gky1292. PubMed PMID: 30590705; PMCID: PMC6411937. https://www.ncbi.nlm.nih.gov/pubmed/30590705   

Liu J, Wang T, Creighton CJ, Wu SP, Ray M, Janardhan KS, Willson CJ, Cho SN, Castro PD, Ittmann MM, Li JL, Davis RJ, DeMayo FJ. JNK(1/2) represses Lkb(1)-deficiency-induced lung squamous cell carcinoma progression. Nat Commun. 2019;10(1):2148. Epub 2019/05/16. doi: 10.1038/s41467-019-09843-1. PubMed PMID: 31089135; PMCID: PMC6517592. https://www.ncbi.nlm.nih.gov/pubmed/31089135   

Liu P, Luk K, Shin M, Idrizi F, Kwok S, Roscoe B, Mintzer E, Suresh S, Morrison K, Frazao JB, Bolukbasi MF, Ponnienselvan K, Luban J, Zhu LJ, Lawson ND, Wolfe SA. Enhanced Cas12a editing in mammalian cells and zebrafish. Nucleic Acids Res. 2019;47(8):4169-80. Epub 2019/03/21. doi: 10.1093/nar/gkz184. PubMed PMID: 30892626; PMCID: PMC6486634. https://www.ncbi.nlm.nih.gov/pubmed/30892626   

Luban J. The hidden cost of genetic resistance to HIV-1. Nat Med. 2019;25(6):878-9. Epub 2019/06/05. doi: 10.1038/s41591-019-0481-8. PubMed PMID: 31160816. https://www.ncbi.nlm.nih.gov/pubmed/31160816 

Luciano AK, Guertin DA. Oncogenic AKTivation by methylation. Nat Cell Biol. 2019;21(2):114-5. Epub 2019/01/30. doi: 10.1038/s41556-019-0275-8. PubMed PMID: 30692624.
https://www.ncbi.nlm.nih.gov/pubmed/30692624    

Ma L, Pak ML, Ou J, Yu J, St Louis P, Shan Y, Hutchinson L, Li S, Brehm MA, Zhu LJ, Green MR. Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells. Proc Natl Acad Sci U S A. 2019;116(21):10482-7. Epub 2019/05/10. doi: 10.1073/pnas.1903550116. PubMed PMID: 31068472; PMCID: PMC6535024.
https://www.ncbi.nlm.nih.gov/pubmed/31068472    

McDougall WM, Perreira JM, Hung HF, Vertii A, Xiaofei E, Zimmerman W, Kowalik TF, Doxsey S, Brass AL. Viral Infection or IFN-alpha Alters Mitotic Spindle Orientation by Modulating Pericentrin Levels. iScience. 2019;12:270-9. Epub 2019/02/05. doi: 10.1016/j.isci.2019.01.025. PubMed PMID: 30716700; PMCID: PMC6360249.
https://www.ncbi.nlm.nih.gov/pubmed/30716700    

Megquier K, Genereux DP, Hekman J, Swofford R, Turner-Maier J, Johnson J, Alonso J, Li X, Morrill K, Anguish LJ, Koltookian M, Logan B, Sharp CR, Ferrer L, Lindblad-Toh K, Meyers-Wallen VN, Hoffman A, Karlsson EK. BarkBase: Epigenomic Annotation of Canine Genomes. Genes (Basel). 2019;10(6). Epub 2019/06/12. doi: 10.3390/genes10060433. PubMed PMID: 31181663. https://www.ncbi.nlm.nih.gov/pubmed/31181663   

Min SY, Learnard H, Kant S, Gealikman O, Rojas-Rodriguez R, DeSouza T, Desai A, Keaney JF, Jr., Corvera S, Craige SM. Exercise Rescues Gene Pathways Involved in Vascular Expansion and Promotes Functional Angiogenesis in Subcutaneous White Adipose Tissue. Int J Mol Sci. 2019;20(8). Epub 2019/04/28. doi: 10.3390/ijms20082046. PubMed PMID: 31027261; PMCID: PMC6515240.
https://www.ncbi.nlm.nih.gov/pubmed/31027261    

Mookerjee-Basu J, Hua X, Ge L, Nicolas E, Li Q, Czyzewicz P, Zhongping D, Peri S, FuxmanBass JI, Walhout AJM, Kappes DJ. Functional Conservation of a Developmental Switch in Mammals since the Jurassic Age. Mol Biol Evol. 2019;36(1):39-53. Epub 2018/10/09. doi: 10.1093/molbev/msy191. PubMed PMID: 30295892; PMCID: PMC6340473.
https://www.ncbi.nlm.nih.gov/pubmed/30295892    

Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W. CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling. Genome Med. 2019;11(1):21. Epub 2019/04/17. doi: 10.1186/s13073-019-0627-9. PubMed PMID: 30987660; PMCID: PMC6466773.
https://www.ncbi.nlm.nih.gov/pubmed/30987660    

Muniraju M, Mutsvunguma LZ, Foley J, Escalante GM, Rodriguez E, Nabiee R, Totonchy J, Mulama DH, Nyagol J, Wussow F, Barasa AK, Brehm M, Ogembo JG. Kaposi Sarcoma-associated Herpesvirus Glycoprotein H is Indispensable for Infection of Epithelial, Endothelial, and Fibroblast Cell Types. J Virol. 2019. Epub 2019/05/31. doi: 10.1128/JVI.00630-19. PubMed PMID: 31142670. https://www.ncbi.nlm.nih.gov/pubmed/31142670   

Nelson C, Ambros V. Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity. Development. 2019;146(5). Epub 2019/02/17. doi: 10.1242/dev.172031. PubMed PMID: 30770392; PMCID: PMC6432665.
https://www.ncbi.nlm.nih.gov/pubmed/30770392    

Noon JB, Schwarz EM, Ostroff GR, Aroian RV. A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection. PLoS Negl Trop Dis. 2019;13(4):e0007345. Epub 2019/04/23. doi: 10.1371/journal.pntd.0007345. PubMed PMID: 31009474; PMCID: PMC6497320.
https://www.ncbi.nlm.nih.gov/pubmed/31009474   

Ou J, Zhu LJ. trackViewer: a Bioconductor package for interactive and integrative visualization of multi-omics data. Nat Methods. 2019;16(6):453-4. Epub 2019/05/28. doi: 10.1038/s41592-019-0430-y. PubMed PMID: 31133757. https://www.ncbi.nlm.nih.gov/pubmed/31133757   

Pan SC, Ward DV, Yin Y, Hu Y, Elfawal MA, Clark RE, Aroian RV. Cognitive and Microbiome Impacts of Experimental Ancylostoma ceylanicum Hookworm Infections in Hamsters. Sci Rep. 2019;9(1):7868. Epub 2019/05/28. doi: 10.1038/s41598-019-44301-4. PubMed PMID: 31133690; PMCID: PMC6536493.
https://www.ncbi.nlm.nih.gov/pubmed/31133690    

Parhad SS, Theurkauf WE. Rapid evolution and conserved function of the piRNA pathway. Open Biol. 2019;9(1):180181. Epub 2019/04/09. doi: 10.1098/rsob.180181. PubMed PMID: 30958115; PMCID: PMC6367137. https://www.ncbi.nlm.nih.gov/pubmed/30958115   

Picariello T, Brown JM, Hou Y, Swank G, Cochran DA, King OD, Lechtreck K, Pazour GJ, Witman GB. A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia. J Cell Sci. 2019;132(3). Epub 2019/01/20. doi: 10.1242/jcs.220749. PubMed PMID: 30659111; PMCID: PMC6382014. https://www.ncbi.nlm.nih.gov/pubmed/30659111

Qu M, Lu P, Bevell K, Fogarty K, Lifshitz L, Shi F, ZhuGe R. Smooth muscle cell-specific TMEM16A deletion does not alter Ca2+ signaling, uterine contraction, gestation length or litter size in micedagger. Biol Reprod. 2019. Epub 2019/06/09. doi: 10.1093/biolre/ioz096. PubMed PMID: 31175367. https://www.ncbi.nlm.nih.gov/pubmed/31175367   

Quitadamo B, Peters PJ, Koch M, Luzuriaga K, Cheng-Mayer C, Clapham PR, Gonzalez-Perez MP. No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications. Arch Virol. 2019;164(2):473-82. Epub 2018/11/12. doi: 10.1007/s00705-018-4094-1. PubMed PMID: 30415390; PMCID: PMC6369005.
https://www.ncbi.nlm.nih.gov/pubmed/30415390    

Russell MA, Redick SD, Blodgett DM, Richardson SJ, Leete P, Krogvold L, Dahl-Jorgensen K, Bottino R, Brissova M, Spaeth JM, Babon JAB, Haliyur R, Powers AC, Yang C, Kent SC, Derr AG, Kucukural A, Garber MG, Morgan NG, Harlan DM. HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet beta-Cells From Donors With Type 1 Diabetes. Diabetes. 2019;68(5):988-1001. Epub 2019/03/06. doi: 10.2337/db18-0686. PubMed PMID: 30833470; PMCID: PMC6477908.
https://www.ncbi.nlm.nih.gov/pubmed/30833470    

Sanchez-Gurmaches J, Martinez Calejman C, Jung SM, Li H, Guertin DA. Brown fat organogenesis and maintenance requires AKT1 and AKT2. Mol Metab. 2019;23:60-74. Epub 2019/03/06. doi: 10.1016/j.molmet.2019.02.004. PubMed PMID: 30833219; PMCID: PMC6480051. https://www.ncbi.nlm.nih.gov/pubmed/30833219   

Shi L, Zhou T, Huang Q, Zhang S, Li W, Zhang L, Hess RA, Pazour GJ, Zhang Z. Intraflagellar transport protein 74 is essential for spermatogenesis and male fertility in micedagger. Biol Reprod. 2019;101(1):188-99. Epub 2019/04/21. doi: 10.1093/biolre/ioz071. PubMed PMID: 31004481; PMCID: PMC6614581. https://www.ncbi.nlm.nih.gov/pubmed/31004481   

Singh RK, Fan J, Gioacchini N, Watanabe S, Bilsel O, Peterson CL. Transient Kinetic Analysis of SWR1C-Catalyzed H2A.Z Deposition Unravels the Impact of Nucleosome Dynamics and the Asymmetry of Histone Exchange. Cell Rep. 2019;27(2):374-86 e4. Epub 2019/04/11. doi: 10.1016/j.celrep.2019.03.035. PubMed PMID: 30970243; PMCID: PMC6545893. https://www.ncbi.nlm.nih.gov/pubmed/30970243   

Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Haring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I. Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019;364(6444). Epub 2019/06/07. doi: 10.1126/science.aas9536. PubMed PMID: 31171666. https://www.ncbi.nlm.nih.gov/pubmed/31171666   

Sztul E, Chen PW, Casanova JE, Cherfils J, Dacks JB, Lambright DG, Lee FS, Randazzo PA, Santy LC, Schurmann A, Wilhelmi I, Yohe ME, Kahn RA. ARF GTPases and their GEFs and GAPs: concepts and challenges. Mol Biol Cell. 2019;30(11):1249-71. Epub 2019/05/16. doi: 10.1091/mbc.E18-12-0820. PubMed PMID: 31084567.
https://www.ncbi.nlm.nih.gov/pubmed/31084567    

Thavalingam A, Cheng Z, Garcia B, Huang X, Shah M, Sun W, Wang M, Harrington L, Hwang S, Hidalgo-Reyes Y, Sontheimer EJ, Doudna J, Davidson AR, Moraes TF, Wang Y, Maxwell KL. Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun. 2019;10(1):2806. Epub 2019/06/28. doi: 10.1038/s41467-019-10577-3. PubMed PMID: 31243272; PMCID: PMC6594998. https://www.ncbi.nlm.nih.gov/pubmed/31243272   

Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, Zhang G. Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis. Cancer Res. 2019;79(8):1822-30. Epub 2019/02/26. doi: 10.1158/0008-5472.CAN-18-3221. PubMed PMID: 30803995; PMCID: PMC6467714. https://www.ncbi.nlm.nih.gov/pubmed/30803995   

Wehrle A, Witkos TM, Unger S, Schneider J, Follit JA, Hermann J, Welting T, Fano V, Hietala M, Vatanavicharn N, Schoner K, Spranger J, Schmidts M, Zabel B, Pazour GJ, Bloch-Zupan A, Nishimura G, Superti-Furga A, Lowe M, Lausch E. Hypomorphic mutations of TRIP11 cause odontochondrodysplasia. JCI Insight. 2019;4(3). Epub 2019/02/08. doi: 10.1172/jci.insight.124701. PubMed PMID: 30728324; PMCID: PMC6413787. https://www.ncbi.nlm.nih.gov/pubmed/30728324   

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