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Recent Publications

Recent publications shown with PMM Bioinformatics Core members as collaborators/co-authors.

  1. Jangalwe S, Kapoor VN, Xu J, Girnius N, Kennedy NJ, Edwards YJK, Welsh RM, Davis RJ, Brehm MA. (2019). Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim. J Immunology pii: ji1800278.
  2. Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline R, Kim JK, Czech MP. (2018). CRISPR delivery particles targeting Nrip1 in adipose cells to enhance energy expenditure. Journal of Biological Chemistry 293:17291-17305.
  3. Girnius N, Edwards YJK, Garlick DS, Davis RJ. (2018). The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation. eLife 7, pii: e36389.
  4. Girnius N, Edwards YJK, Davis RJ. (2018). The cJun NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution. Cell Death and Differentiation 25:1702-1715.
  5. Venkatesan AM, Vyas R, Gramann A, Dresser K, Gujja S, Bhatnagar S, Chhangawala S, Gomes C, Xi HS, Lian CG, Houvras Y, Edwards YJK, Deng A, Green M, Ceol CJ. (2018). Ligand-activated BMP signaling inhibits cell differentiation and cell death to promote melanoma. Journal Clinical Investigation 128:294-308.
  6. Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. (2018). Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis. Cell Metabolism 27:195-209.e6.
  7. Fitzgibbons TP, Edwards YJK, Shaw P, Iskandar A, Ahmed M, Bote J, Shah T, Sinha S, Gerszten RE, Keaney JF, Zile M, Aurigemma GP. (2017). Activation of Inflammatory and Pro-thrombotic Pathways in Acute Stress Cardiomyopathy. Frontiers in Cardiovascular Medicine 4:49.
  8. Vernia S, Edwards YJK, Han MS, Cavanagh-Kyros J, Barrett T, Kim JK and Davis RJ. (2016). An alternative splicing program promotes adipose tissue thermogenesis. Elife 5, pii: e17672.
  9. Mansur F, Ivshina M, Gu W, Schaevitz L, Gujja S, Edwards YJK, Richter JD. (2016). Gld2-catalyzed 3’ Mono-adenylation of miRNAs in the Hippocampus has no Detectable Effect on their Stability or on Animal Behavior. RNA, 22:1492-1499.
  10. Smulan L, Ding W, Freinkman E, Gujja S, Edwards YJK, Walker A. (2016). Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation. Cell Reports 16(1):9-18.
  11. Roth Flach RJ, Guo CA, Danai LV, Yawe JC, Gujja S, Edwards YJK, Czech MP. (2016). Endothelial MAP4K4 is critical for lymphatic vascular development and function. Molecular and Cellular Biology 36:1740-1749.