Search Close Search
Search Close Search
Page Menu

Publications 2020

Armstrong J, Hickey G, Diekhans M, Fiddes IT, Novak AM, Deran A, Fang Q, Xie D, Feng S, Stiller J, Genereux D, Johnson J, Marinescu VD, Alfoldi J, Harris RS, Lindblad-Toh K, Haussler D, Karlsson E, Jarvis ED, Zhang G, Paten B. Progressive Cactus is a multiple-genome aligner for the thousand-genome era. Nature. 2020;587(7833):246-51. Epub 2020/11/13. doi: 10.1038/s41586-020-2871-y. PubMed PMID: 33177663; PMCID: PMC7673649.   

Batista TM, Dagdeviren S, Carroll SH, Cai W, Melnik VY, Noh HL, Saengnipanthkul S, Kim JK, Kahn CR, Lee RT. Arrestin domain-containing 3 (Arrdc3) modulates insulin action and glucose metabolism in liver. Proc Natl Acad Sci U S A. 2020;117(12):6733-40. Epub 2020/03/12. doi: 10.1073/pnas.1922370117. PubMed PMID: 32156724; PMCID: PMC7104271.   

Biscans A, Caiazzi J, Davis S, McHugh N, Sousa J, Khvorova A. The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy. Nucleic Acids Res. 2020;48(14):7665-80. Epub 2020/07/17. doi: 10.1093/nar/gkaa595. PubMed PMID: 32672813; PMCID: PMC7430635.   

Biscans A, Caiazzi J, McHugh N, Hariharan V, Muhuri M, Khvorova A. Docosanoic acid conjugation to siRNA enables functional and safe delivery to skeletal and cardiac muscles. Mol Ther. 2020. Epub 2020/12/22. doi: 10.1016/j.ymthe.2020.12.023. PubMed PMID: 33348054.   

Bose S, Volpatti LR, Thiono D, Yesilyurt V, McGladrigan C, Tang Y, Facklam A, Wang A, Jhunjhunwala S, Veiseh O, Hollister-Lock J, Bhattacharya C, Weir GC, Greiner DL, Langer R, Anderson DG. A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells. Nat Biomed Eng. 2020;4(8):814-26. Epub 2020/04/02. doi: 10.1038/s41551-020-0538-5. PubMed PMID: 32231313.   

Calejman CM, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villen J, Wellen KE, Guertin DA. Author Correction: mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nat Commun. 2020;11(1):4585. Epub 2020/09/10. doi: 10.1038/s41467-020-18510-9. PubMed PMID: 32901020; PMCID: PMC7479589.   

Campuzano A, Zhang H, Ostroff GR, Dos Santos Dias L, Wuthrich M, Klein BS, Yu JJ, Lara HH, Lopez-Ribot JL, Hung CY. CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection. J Immunol. 2020;204(12):3296-306. Epub 2020/05/03. doi: 10.4049/jimmunol.1900793. PubMed PMID: 32358020; PMCID: PMC7323849.   

Carlisle AE, Lee N, Matthew-Onabanjo AN, Spears ME, Park SJ, Youkana D, Doshi MB, Peppers A, Li R, Joseph AB, Smith M, Simin K, Zhu LJ, Greer PL, Shaw LM, Kim D. Selenium detoxification is required for cancer-cell survival. Nat Metab. 2020;2(7):603-11. Epub 2020/07/23. doi: 10.1038/s42255-020-0224-7. PubMed PMID: 32694795; PMCID: PMC7455022.   

Carreiro S, Marvel-Coen J, Lee R, Chapman B, Ambros V. Circulating microRNA Profiles in Acetaminophen Toxicity. J Med Toxicol. 2020;16(2):177-87. Epub 2019/12/04. doi: 10.1007/s13181-019-00739-6. PubMed PMID: 31792846; PMCID: PMC7099119.   

Chang ML, Yang Z, Yang SS. Roles of Adipokines in Digestive Diseases: Markers of Inflammation, Metabolic Alteration and Disease Progression. Int J Mol Sci. 2020;21(21). Epub 2020/11/11. doi: 10.3390/ijms21218308. PubMed PMID: 33167521; PMCID: PMC7663948.   

Chauhan G, McClure J, Hekman J, Marsh PW, Bailey JA, Daniels RF, Genereux DP, Karlsson EK. Combining Citizen Science and Genomics to Investigate Tick, Pathogen, and Commensal Microbiome at Single-Tick Resolution. Front Genet. 2019;10:1322. Epub 2020/02/11. doi: 10.3389/fgene.2019.01322. PubMed PMID: 32038704; PMCID: PMC6985576.   

Chen HJ, Li Q, Nirala NK, Ip YT. The Snakeskin-Mesh Complex of Smooth Septate Junction Restricts Yorkie to Regulate Intestinal Homeostasis in Drosophila. Stem Cell Reports. 2020;14(5):828-44. Epub 2020/04/25. doi: 10.1016/j.stemcr.2020.03.021. PubMed PMID: 32330445; PMCID: PMC7220990.   

Cheung P, Xiol J, Dill MT, Yuan WC, Panero R, Roper J, Osorio FG, Maglic D, Li Q, Gurung B, Calogero RA, Yilmaz OH, Mao J, Camargo FD. Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer. Cell Stem Cell. 2020;27(4):590-604 e9. Epub 2020/07/31. doi: 10.1016/j.stem.2020.07.003. PubMed PMID: 32730753.   

Chrudinova M, Moreau F, Noh HL, Panikova T, Zakova L, Friedline RH, Valenzuela FA, Kim JK, Jiracek J, Kahn CR, Altindis E. Characterization of viral insulins reveals white adipose tissue-specific effects in mice. Mol Metab. 2020;44:101121. Epub 2020/11/22. doi: 10.1016/j.molmet.2020.101121. PubMed PMID: 33220491; PMCID: PMC7770979.   

Corrigan JK, Ramachandran D, He Y, Palmer CJ, Jurczak MJ, Chen R, Li B, Friedline RH, Kim JK, Ramsey JJ, Lantier L, McGuinness OP, Mouse Metabolic Phenotyping Center Energy Balance Working G, Banks AS. A big-data approach to understanding metabolic rate and response to obesity in laboratory mice. Elife. 2020;9. Epub 2020/05/02. doi: 10.7554/eLife.53560. PubMed PMID: 32356724; PMCID: PMC7274785.   

Crespo M, Gonzalez-Teran B, Nikolic I, Mora A, Folgueira C, Rodriguez E, Leiva-Vega L, Pintor-Chocano A, Fernandez-Chacon M, Ruiz-Garrido I, Cicuendez B, Tomas-Loba A, N AG, Caballero-Molano A, Beiroa D, Hernandez-Cosido L, Torres JL, Kennedy NJ, Davis RJ, Benedito R, Marcos M, Nogueiras R, Hidalgo A, Matesanz N, Leiva M, Sabio G. Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. Elife. 2020;9. Epub 2020/12/09. doi: 10.7554/eLife.59258. PubMed PMID: 33287957; PMCID: PMC7723411.   

Cruz-Gordillo P, Honeywell ME, Harper NW, Leete T, Lee MJ. ELP-dependent expression of MCL1 promotes resistance to EGFR inhibition in triple-negative breast cancer cells. Sci Signal. 2020;13(658). Epub 2020/11/19. doi: 10.1126/scisignal.abb9820. PubMed PMID: 33203722; PMCID: PMC7685180.   

Csorgo B, Leon LM, Chau-Ly IJ, Vasquez-Rifo A, Berry JD, Mahendra C, Crawford ED, Lewis JD, Bondy-Denomy J. A compact Cascade-Cas3 system for targeted genome engineering. Nat Methods. 2020;17(12):1183-90. Epub 2020/10/21. doi: 10.1038/s41592-020-00980-w. PubMed PMID: 33077967.   

Cubero FJ, Mohamed MR, Woitok MM, Zhao G, Hatting M, Nevzorova YA, Chen C, Haybaeck J, de Bruin A, Avila MA, Boekschoten MV, Davis RJ, Trautwein C. Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma. Hepatol Commun. 2020;4(6):834-51. Epub 2020/06/04. doi: 10.1002/hep4.1495. PubMed PMID: 32490320; PMCID: PMC7262317   

Czech MP. Mechanisms of insulin resistance related to white, beige, and brown adipocytes. Mol Metab. 2020;34:27-42. Epub 2020/03/18. doi: 10.1016/j.molmet.2019.12.014. PubMed PMID: 32180558; PMCID: PMC6997501.   

Damas J, Hughes GM, Keough KC, Painter CA, Persky NS, Corbo M, Hiller M, Koepfli KP, Pfenning AR, Zhao H, Genereux DP, Swofford R, Pollard KS, Ryder OA, Nweeia MT, Lindblad-Toh K, Teeling EC, Karlsson EK, Lewin HA. Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates. Proc Natl Acad Sci U S A. 2020;117(36):22311-22. Epub 2020/08/23. doi: 10.1073/pnas.2010146117. PubMed PMID: 32826334; PMCID: PMC7486773.   

Damas J, Hughes GM, Keough KC, Painter CA, Persky NS, Corbo M, Hiller M, Koepfli KP, Pfenning AR, Zhao H, Genereux DP, Swofford R, Pollard KS, Ryder OA, Nweeia MT, Lindblad-Toh K, Teeling EC, Karlsson EK, Lewin HA. Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates. bioRxiv. 2020. Epub 2020/06/09. doi: 10.1101/2020.04.16.045302. PubMed PMID: 32511356; PMCID: PMC7263403.   

Darp R, Ceol C. Making a Melanoma: molecular and cellular changes underlying melanoma initiation. Pigment Cell Melanoma Res. 2020. Epub 2020/12/08. doi: 10.1111/pcmr.12950. PubMed PMID: 33283422.   

Das DK, Bulow U, Diehl WE, Durham ND, Senjobe F, Chandran K, Luban J, Munro JB. Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding. PLoS Biol. 2020;18(2):e3000626. Epub 2020/02/11. doi: 10.1371/journal.pbio.3000626. PubMed PMID: 32040508; PMCID: PMC7034923.   

Davidson AR, Lu WT, Stanley SY, Wang J, Mejdani M, Trost CN, Hicks BT, Lee J, Sontheimer EJ. Anti-CRISPRs: Protein Inhibitors of CRISPR-Cas Systems. Annu Rev Biochem. 2020;89:309-32. Epub 2020/03/19. doi: 10.1146/annurev-biochem-011420-111224. PubMed PMID: 32186918.   

Desai PB, Stuck MW, Lv B, Pazour GJ. Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling. J Cell Biol. 2020;219(7). Epub 2020/05/22. doi: 10.1083/jcb.201912104. PubMed PMID: 32435793; PMCID: PMC7337509.   

Dobson HE, Dias LDS, Kohn EM, Fites S, Wiesner DL, Dileepan T, Kujoth GC, Abraham A, Ostroff GR, Klein BS, Wuthrich M. Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance. Mucosal Immunol. 2020;13(3):518-29. Epub 2020/01/05. doi: 10.1038/s41385-019-0244-3. PubMed PMID: 31900406; PMCID: PMC7183437.   

Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB. Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics. Viruses. 2020;12(1). Epub 2020/01/19. doi: 10.3390/v12010103. PubMed PMID: 31952255; PMCID: PMC7019799.   

Fazzalari A, Basadonna G, Kucukural A, Tanriverdi K, Koupenova M, Pozzi N, Kakuturu J, Friedrich AU, Korstanje R, Fowler N, Belant JL, Beyer DE, Jr., Brooks MB, Dickson EW, Blackwood M, Mueller C, Palesty JA, Freedman JE, Cahan MA. A Translational Model for Venous Thromboembolism: MicroRNA Expression in Hibernating Black Bears. J Surg Res. 2021;257:203-12. Epub 2020/08/29. doi: 10.1016/j.jss.2020.06.027. PubMed PMID: 32858321.   

Frantz WT, Ceol CJ. From Tank to Treatment: Modeling Melanoma in Zebrafish. Cells. 2020;9(5). Epub 2020/05/28. doi: 10.3390/cells9051289. PubMed PMID: 32455885; PMCID: PMC7290816.   

Ghanta KS, Mello CC. Melting dsDNA Donor Molecules Greatly Improves Precision Genome Editing in Caenorhabditis elegans. Genetics. 2020;216(3):643-50. Epub 2020/09/24. doi: 10.1534/genetics.120.303564. PubMed PMID: 32963112; PMCID: PMC7648581.   

Giese GE, Walker MD, Ponomarova O, Zhang H, Li X, Minevich G, Walhout AJ. Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor. Elife. 2020;9. Epub 2020/10/06. doi: 10.7554/eLife.60259. PubMed PMID: 33016879; PMCID: PMC7561351.   

Gil A, Kamga L, Chirravuri-Venkata R, Aslan N, Clark F, Ghersi D, Luzuriaga K, Selin LK. Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor alpha and beta Repertoires. mBio. 2020;11(2). Epub 2020/03/19. doi: 10.1128/mBio.00250-20. PubMed PMID: 32184241; PMCID: PMC7078470.   

Goodman RP, Markhard AL, Shah H, Sharma R, Skinner OS, Clish CB, Deik A, Patgiri A, Hsu YH, Masia R, Noh HL, Suk S, Goldberger O, Hirschhorn JN, Yellen G, Kim JK, Mootha VK. Hepatic NADH reductive stress underlies common variation in metabolic traits. Nature. 2020;583(7814):122-6. Epub 2020/05/29. doi: 10.1038/s41586-020-2337-2. PubMed PMID: 32461692; PMCID: PMC7536642.   

Guilherme A, Yenilmez B, Bedard AH, Henriques F, Liu D, Lee A, Goldstein L, Kelly M, Nicoloro SM, Chen M, Weinstein L, Collins S, Czech MP. Control of Adipocyte Thermogenesis and Lipogenesis through beta3-Adrenergic and Thyroid Hormone Signal Integration. Cell Rep. 2020;31(5):107598. Epub 2020/05/07. doi: 10.1016/j.celrep.2020.107598. PubMed PMID: 32375048; PMCID: PMC7676427.   

Gupta R, Malvi P, Parajuli KR, Janostiak R, Bugide S, Cai G, Zhu LJ, Green MR, Wajapeyee N. KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity. Proc Natl Acad Sci U S A. 2020;117(22):12341-51. Epub 2020/05/21. doi: 10.1073/pnas.2005156117. PubMed PMID: 32430335; PMCID: PMC7275752.   

Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy B, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J, Eberwine JH, Wyman SK, Wu YL, Kuhn B. Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration. Dev Cell. 2020;53(1):42-59 e11. Epub 2020/02/29. doi: 10.1016/j.devcel.2020.01.030. PubMed PMID: 32109383; PMCID: PMC7346764.   

Han MS, Perry RJ, Camporez JP, Scherer PE, Shulman GI, Gao G, Davis RJ. A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21. Genes Dev. 2021;35(1-2):133-46. Epub 2020/12/19. doi: 10.1101/gad.344556.120. PubMed PMID: 33334822.   

Han MS, White A, Perry RJ, Camporez JP, Hidalgo J, Shulman GI, Davis RJ. Regulation of adipose tissue inflammation by interleukin 6. Proc Natl Acad Sci U S A. 2020;117(6):2751-60. Epub 2020/01/26. doi: 10.1073/pnas.1920004117. PubMed PMID: 31980524; PMCID: PMC7022151.   

Hayden CA, Landrock D, Hung CY, Ostroff G, Fake GM, Walker JH, Kier A, Howard JA. Co-Administration of Injected and Oral Vaccine Candidates Elicits Improved Immune Responses over Either Route Alone. Vaccines (Basel). 2020;8(1). Epub 2020/01/25. doi: 10.3390/vaccines8010037. PubMed PMID: 31973150; PMCID: PMC7157212.   

Henriques F, Bedard AH, Guilherme A, Kelly M, Chi J, Zhang P, Lifshitz LM, Bellve K, Rowland LA, Yenilmez B, Kumar S, Wang Y, Luban J, Weinstein LS, Lin JD, Cohen P, Czech MP. Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis. Cell Rep. 2020;32(5):107998. Epub 2020/08/07. doi: 10.1016/j.celrep.2020.107998. PubMed PMID: 32755590; PMCID: PMC7433376.   

Hester MM, Lee CK, Abraham A, Khoshkenar P, Ostroff GR, Levitz SM, Specht CA. Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens. Vaccine. 2020;38(3):620-6. Epub 2019/11/09. doi: 10.1016/j.vaccine.2019.10.051. PubMed PMID: 31699504; PMCID: PMC6954324.   

Hien A, Molinaro G, Liu B, Huber KM, Richter JD. Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP. Mol Autism. 2020;11(1):78. Epub 2020/10/16. doi: 10.1186/s13229-020-00384-9. PubMed PMID: 33054857; PMCID: PMC7556950.   

Holdorf AD, Higgins DP, Hart AC, Boag PR, Pazour GJ, Walhout AJM, Walker AK. WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data. Genetics. 2020;214(2):279-94. Epub 2019/12/08. doi: 10.1534/genetics.119.302919. PubMed PMID: 31810987; PMCID: PMC7017019.   

Hsiao WY, Jung SM, Tang Y, Haley JA, Li R, Li H, Calejman CM, Sanchez-Gurmaches J, Hung CM, Luciano AK, DeMambro V, Wellen KE, Rosen CJ, Zhu LJ, Guertin DA. The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development. Cell Rep. 2020;33(1):108223. Epub 2020/10/08. doi: 10.1016/j.celrep.2020.108223. PubMed PMID: 33027655; PMCID: PMC7607535.   

Iwanaga R, Truong BT, Hsu JY, Lambert KA, Vyas R, Orlicky D, Shellman YG, Tan AC, Ceol C, Artinger KB. Loss of prdm1a accelerates melanoma onset and progression. Mol Carcinog. 2020;59(9):1052-63. Epub 2020/06/21. doi: 10.1002/mc.23236. PubMed PMID: 32562448.   

Jiang L, Wang YJ, Zhao J, Uehara M, Hou Q, Kasinath V, Ichimura T, Banouni N, Dai L, Li X, Greiner DL, Shultz LD, Zhang X, Sun ZJ, Curtin I, Vangos NE, Yeoh ZC, Geffken EA, Seo HS, Liu ZX, Heffron GJ, Shah K, Dhe-Paganon S, Abdi R. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell. 2020;183(5):1219-33 e18. Epub 2020/11/27. doi: 10.1016/j.cell.2020.10.045. PubMed PMID: 33242418.   

Jiang T, Henderson JM, Coote K, Cheng Y, Valley HC, Zhang XO, Wang Q, Rhym LH, Cao Y, Newby GA, Bihler H, Mense M, Weng Z, Anderson DG, McCaffrey AP, Liu DR, Xue W. Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope. Nat Commun. 2020;11(1):1979. Epub 2020/04/26. doi: 10.1038/s41467-020-15892-8. PubMed PMID: 32332735; PMCID: PMC7181807.   

Krietenstein N, Abraham S, Venev SV, Abdennur N, Gibcus J, Hsieh TS, Parsi KM, Yang L, Maehr R, Mirny LA, Dekker J, Rando OJ. Ultrastructural Details of Mammalian Chromosome Architecture. Mol Cell. 2020;78(3):554-65 e7. Epub 2020/03/28. doi: 10.1016/j.molcel.2020.03.003. PubMed PMID: 32213324; PMCID: PMC7222625.   

Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W. Depletion of TRRAP Induces p53-Independent Senescence in Liver Cancer by Down-Regulating Mitotic Genes. Hepatology. 2020;71(1):275-90. Epub 2019/06/13. doi: 10.1002/hep.30807. PubMed PMID: 31188495; PMCID: PMC6906267.   

Lawson ND, Li R, Shin M, Grosse A, Yukselen O, Stone OA, Kucukural A, Zhu L. An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes. Elife. 2020;9. Epub 2020/08/25. doi: 10.7554/eLife.55792. PubMed PMID: 32831172; PMCID: PMC7486121.   

Leech CM, Flynn MJ, Arsenault HE, Ou J, Liu H, Zhu LJ, Benanti JA. The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network. PLoS Genet. 2020;16(4):e1008600. Epub 2020/04/29. doi: 10.1371/journal.pgen.1008600. PubMed PMID: 32343701; PMCID: PMC7209309.   

Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA. Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Rep. 2020;32(2):107894. Epub 2020/07/16. doi: 10.1016/j.celrep.2020.107894. PubMed PMID: 32668238; PMCID: PMC7359783.   

Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BL. Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events. Science. 2020. Epub 2020/12/12. doi: 10.1126/science.abe3261. PubMed PMID: 33303686.   

Li HJ, Ray SK, Kucukural A, Gradwohl G, Leiter AB. Reduced Neurog3 Gene Dosage Shifts Enteroendocrine Progenitor Towards Goblet Cell Lineage in the Mouse Intestine. Cell Mol Gastroenterol Hepatol. 2020. Epub 2020/08/22. doi: 10.1016/j.jcmgh.2020.08.006. PubMed PMID: 32822913.   

Li J, Lambright DG, Hsu VW. Coordination of Grp1 recruitment mechanisms by its phosphorylation. Mol Biol Cell. 2020;31(25):2816-25. Epub 2020/10/08. doi: 10.1091/mbc.E20-03-0173. PubMed PMID: 33026967.   

Li Q, Sun Y, Jarugumilli GK, Liu S, Dang K, Cotton JL, Xiol J, Chan PY, DeRan M, Ma L, Li R, Zhu LJ, Li JH, Leiter AB, Ip YT, Camargo FD, Luo X, Johnson RL, Wu X, Mao J. Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell. 2020;26(5):675-92 e8. Epub 2020/04/08. doi: 10.1016/j.stem.2020.03.002. PubMed PMID: 32259481; PMCID: PMC7310193.   

Li R, Hu K, Liu H, Green MR, Zhu LJ. OneStopRNAseq: A Web Application for Comprehensive and Efficient Analyses of RNA-Seq Data. Genes (Basel). 2020;11(10). Epub 2020/10/08. doi: 10.3390/genes11101165. PubMed PMID: 33023248; PMCID: PMC7650687.   

Lin AE, Diehl WE, Cai Y, Finch CL, Akusobi C, Kirchdoerfer RN, Bollinger L, Schaffner SF, Brown EA, Saphire EO, Andersen KG, Kuhn JH, Luban J, Sabeti PC. Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111. Viruses. 2020;12(1). Epub 2020/01/19. doi: 10.3390/v12010105. PubMed PMID: 31952352; PMCID: PMC7019320.   

Liu WH, Zheng J, Feldman JL, Klein MA, Kuznetsov VI, Peterson CL, Griffin PR, Denu JM. Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6. Nat Commun. 2020;11(1):5244. Epub 2020/10/18. doi: 10.1038/s41467-020-19018-y. PubMed PMID: 33067423; PMCID: PMC7568541.   

Lord KA, Larson G, Coppinger RP, Karlsson EK. The History of Farm Foxes Undermines the Animal Domestication Syndrome. Trends Ecol Evol. 2020;35(2):125-36. Epub 2019/12/08. doi: 10.1016/j.tree.2019.10.011. PubMed PMID: 31810775.   

Lord KA, Larson G, Karlsson EK. Brain Size Does Not Rescue Domestication Syndrome. Trends Ecol Evol. 2020;35(12):1061-2. Epub 2020/11/02. doi: 10.1016/j.tree.2020.10.004. PubMed PMID: 33129589.   

Lord KA, Larson G, Karlsson EK. Reply to Zeder and Trut et al.: An Attractive Hypothesis in Need of Evidence. Trends Ecol Evol. 2020;35(8):651-2. Epub 2020/06/11. doi: 10.1016/j.tree.2020.05.008. PubMed PMID: 32517961   

Luban J, Sattler RA, Muhlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz SW. The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines. Virus Res. 2021;292:198246. Epub 2020/11/30. doi: 10.1016/j.virusres.2020.198246. PubMed PMID: 33249060; PMCID: PMC7690341.   

Luo J, Weaver MS, Fitzgibbons TP, Aouadi M, Czech MP, Allen MD. Immunotherapy for Infarcts: In Vivo Postinfarction Macrophage Modulation Using Intramyocardial Microparticle Delivery of Map4k4 Small Interfering RNA. Biores Open Access. 2020;9(1):258-68. Epub 2020/12/31. doi: 10.1089/biores.2020.0037. PubMed PMID: 33376632; PMCID: PMC7757732.   

Magaletta ME, Siller R, Maehr R. Differentiation of human pluripotent stem cells toward pharyngeal endoderm derivatives: Current status and potential. Curr Top Dev Biol. 2020;138:175-208. Epub 2020/03/30. doi: 10.1016/bs.ctdb.2020.01.004. PubMed PMID: 32220297.   

Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 2020;369(6510). Epub 2020/09/19. doi: 10.1126/science.aas8995. PubMed PMID: 32943500.   

Maire T, Allertz T, Betjes MA, Youk H. Dormancy-to-death transition in yeast spores occurs due to gradual loss of gene-expressing ability. Mol Syst Biol. 2020;16(11):e9245. Epub 2020/11/19. doi: 10.15252/msb.20199245. PubMed PMID: 33206464; PMCID: PMC7673291.   

Manieri E, Folgueira C, Rodriguez ME, Leiva-Vega L, Esteban-Lafuente L, Chen C, Cubero FJ, Barrett T, Cavanagh-Kyros J, Seruggia D, Rosell A, Sanchez-Cabo F, Gomez MJ, Monte MJ, JJ GM, Davis RJ, Mora A, Sabio G. JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma. Proc Natl Acad Sci U S A. 2020;117(28):16492-9. Epub 2020/07/01. doi: 10.1073/pnas.2002672117. PubMed PMID: 32601222; PMCID: PMC7368313.   

Mansur F, Alarcon JM, Stackpole EE, Wang R, Richter JD. Noncanonical cytoplasmic poly(A) polymerases regulate RNA levels, alternative RNA processing, and synaptic plasticity but not hippocampal-dependent behaviours. RNA Biol. 2020:1-10. Epub 2020/09/22. doi: 10.1080/15476286.2020.1824061. PubMed PMID: 32954964.   

Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villen J, Wellen KE, Guertin DA. mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nat Commun. 2020;11(1):575. Epub 2020/01/31. doi: 10.1038/s41467-020-14430-w. PubMed PMID: 31996678; PMCID: PMC6989638.   

Mataix-Cols D, Hansen B, Mattheisen M, Karlsson EK, Addington AM, Boberg J, Djurfeldt DR, Halvorsen M, Lichtenstein P, Solem S, Lindblad-Toh K, Nordic OCD, Related Disorders C, Haavik J, Kvale G, Ruck C, Crowley JJ. Nordic OCD & Related Disorders Consortium: Rationale, design, and methods. Am J Med Genet B Neuropsychiatr Genet. 2020;183(1):38-50. Epub 2019/08/20. doi: 10.1002/ajmg.b.32756. PubMed PMID: 31424634; PMCID: PMC6898732.   

McManus M, Karalius B, Patel K, Persaud D, Luzuriaga K, Pediatric HIVACS. Quantitative HIV-1-specific antibodies as predictors of peripheral blood cell-associated HIV-1 DNA concentrations. AIDS. 2020;34(8):1117-26. Epub 2020/04/15. doi: 10.1097/QAD.0000000000002525. PubMed PMID: 32287055; PMCID: PMC7573836.   

Mirza Z, Soto ER, Hu Y, Nguyen TT, Koch D, Aroian RV, Ostroff GR. Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes. Molecules. 2020;25(13). Epub 2020/07/02. doi: 10.3390/molecules25132958. PubMed PMID: 32605043; PMCID: PMC7411854.   

Na H, Zdraljevic S, Tanny RE, Walhout AJM, Andersen EC. Natural variation in a glucuronosyltransferase modulates propionate sensitivity in a C. elegans propionic acidemia model. PLoS Genet. 2020;16(8):e1008984. Epub 2020/08/29. doi: 10.1371/journal.pgen.1008984. PubMed PMID: 32857789; PMCID: PMC7482840.   

Nieblas-Bedolla E, Nayyar N, Singh M, Sullivan RJ, Brastianos PK. Emerging Immunotherapies in the Treatment of Brain Metastases. Oncologist. 2020. Epub 2020/10/27. doi: 10.1002/onco.13575. PubMed PMID: 33103803.   

Nyalwidhe JO, Jurczyk A, Satish B, Redick S, Qaisar N, Trombly MI, Vangala P, Racicot R, Bortell R, Harlan DM, Greiner DL, Brehm MA, Nadler JL, Wang JP. Proteomic and Transcriptional Profiles of Human Stem Cell-Derived beta Cells Following Enteroviral Challenge. Microorganisms. 2020;8(2). Epub 2020/02/26. doi: 10.3390/microorganisms8020295. PubMed PMID: 32093375; PMCID: PMC7074978.   

O'Regan GC, Farag SH, Ostroff GR, Tabrizi SJ, Andre R. Wild-type huntingtin regulates human macrophage function. Sci Rep. 2020;10(1):17269. Epub 2020/10/16. doi: 10.1038/s41598-020-74042-8. PubMed PMID: 33057179; PMCID: PMC7560844.   

Ohainle M, Kim K, Komurlu Keceli S, Felton A, Campbell E, Luban J, Emerman M. TRIM34 restricts HIV-1 and SIV capsids in a TRIM5alpha-dependent manner. PLoS Pathog. 2020;16(4):e1008507. Epub 2020/04/14. doi: 10.1371/journal.ppat.1008507. PubMed PMID: 32282853; PMCID: PMC7179944.   

Ou J, Liu H, Nirala NK, Stukalov A, Acharya U, Green MR, Zhu LJ. dagLogo: An R/Bioconductor package for identifying and visualizing differential amino acid group usage in proteomics data. PLoS One. 2020;15(11):e0242030. Epub 2020/11/07. doi: 10.1371/journal.pone.0242030. PubMed PMID: 33156866; PMCID: PMC7647101.   

Palma P, McManus M, Cotugno N, Rocca S, Rossi P, Luzuriaga K. The HIV-1 antibody response: a footprint of the viral reservoir in children vertically infected with HIV. Lancet HIV. 2020;7(5):e359-e65. Epub 2020/05/11. doi: 10.1016/S2352-3018(20)30100-4. PubMed PMID: 32386722; PMCID: PMC7593885.   

Parhad SS, Yu T, Zhang G, Rice NP, Weng Z, Theurkauf WE. Adaptive Evolution Targets a piRNA Precursor Transcription Network. Cell Rep. 2020;30(8):2672-85 e5. Epub 2020/02/27. doi: 10.1016/j.celrep.2020.01.109. PubMed PMID: 32101744; PMCID: PMC7061269.   

Pazour GJ, Quarmby L, Smith AO, Desai PB, Schmidts M. Cilia in cystic kidney and other diseases. Cell Signal. 2020;69:109519. Epub 2019/12/28. doi: 10.1016/j.cellsig.2019.109519. PubMed PMID: 31881326; PMCID: PMC6953175.   

Picoli CC, Gilio GR, Henriques F, Leal LG, Besson JC, Lopes MA, Franzoi de Moraes SM, Hernandes L, Batista Junior ML, Peres SB. Resistance exercise training induces subcutaneous and visceral adipose tissue browning in Swiss mice. J Appl Physiol (1985). 2020;129(1):66-74. Epub 2020/06/06. doi: 10.1152/japplphysiol.00742.2019. PubMed PMID: 32501777.   

Redick SD, Leehy L, Rittenhouse AR, Blodgett DM, Derr AG, Kucukural A, Garber MG, Shultz LD, Greiner DL, Wang JP, Harlan DM, Bortell R, Jurczyk A. Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice. FASEB J. 2020;34(1):1901-11. Epub 2020/01/10. doi: 10.1096/fj.201901022RR. PubMed PMID: 31914605; PMCID: PMC6972551.   

Richards R, Schwartz HR, Honeywell ME, Stewart MS, Cruz-Gordillo P, Joyce AJ, Landry BD, Lee MJ. Drug antagonism and single-agent dominance result from differences in death kinetics. Nat Chem Biol. 2020;16(7):791-800. Epub 2020/04/07. doi: 10.1038/s41589-020-0510-4. PubMed PMID: 32251407; PMCID: PMC7311243.   

Rinaldi VD, Donnard E, Gellatly K, Rasmussen M, Kucukural A, Yukselen O, Garber M, Sharma U, Rando OJ. An atlas of cell types in the mouse epididymis and vas deferens. Elife. 2020;9. Epub 2020/07/31. doi: 10.7554/eLife.55474. PubMed PMID: 32729827; PMCID: PMC7426093.   

Rojas-Rodriguez R, Ziegler R, DeSouza T, Majid S, Madore AS, Amir N, Pace VA, Nachreiner D, Alfego D, Mathew J, Leung K, Moore Simas TA, Corvera S. PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans. Sci Transl Med. 2020;12(571). Epub 2020/11/27. doi: 10.1126/scitranslmed.aay4145. PubMed PMID: 33239385.   

Rosener B, Sayin S, Oluoch PO, Garcia Gonzalez AP, Mori H, Walhout AJ, Mitchell A. Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host. Elife. 2020;9. Epub 2020/12/01. doi: 10.7554/eLife.59831. PubMed PMID: 33252330; PMCID: PMC7725501.   

Ruiz CF, Montal ED, Haley JA, Bott AJ, Haley JD. SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC. FASEB J. 2020;34(8):10574-89. Epub 2020/06/23. doi: 10.1096/fj.202000052R. PubMed PMID: 32568455.   

Sanders J, Xie Y, Gazzola D, Li H, Abraham A, Flanagan K, Rus F, Miller M, Hu Y, Guynn S, Draper A, Vakalapudi S, Petersson KH, Zarlenga D, Li RW, Urban JF, Jr., Ostroff GR, Zajac A, Aroian RV. A new paraprobiotic-based treatment for control of Haemonchus contortus in sheep. Int J Parasitol Drugs Drug Resist. 2020;14:230-6. Epub 2020/11/27. doi: 10.1016/j.ijpddr.2020.11.004. PubMed PMID: 33242790; PMCID: PMC7695930.   

Schwartz HR, Richards R, Fontana RE, Joyce AJ, Honeywell ME, Lee MJ. Drug GRADE: An Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response Profiles. Cell Rep. 2020;31(12):107800. Epub 2020/06/25. doi: 10.1016/j.celrep.2020.107800. PubMed PMID: 32579927; PMCID: PMC7394473.   

Shah A, Dagdeviren S, Lewandowski JP, Schmider AB, Ricci-Blair EM, Natarajan N, Hundal H, Noh HL, Friedline RH, Vidoudez C, Kim JK, Wagers AJ, Soberman RJ, Lee RT. Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption. iScience. 2020;23(9):101521. Epub 2020/09/15. doi: 10.1016/j.isci.2020.101521. PubMed PMID: 32927265; PMCID: PMC7495107.   

Shah S, Molinaro G, Liu B, Wang R, Huber KM, Richter JD. FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism. Cell Rep. 2020;30(13):4459-72 e6. Epub 2020/04/03. doi: 10.1016/j.celrep.2020.02.076. PubMed PMID: 32234480; PMCID: PMC7179797.   

Shu H, Donnard E, Liu B, Jung S, Wang R, Richter JD. FMRP links optimal codons to mRNA stability in neurons. Proc Natl Acad Sci U S A. 2020;117(48):30400-11. Epub 2020/11/18. doi: 10.1073/pnas.2009161117. PubMed PMID: 33199649; PMCID: PMC7720238.   

Sissaoui S, Yu J, Yan A, Li R, Yukselen O, Kucukural A, Zhu LJ, Lawson ND. Genomic Characterization of Endothelial Enhancers Reveals a Multifunctional Role for NR2F2 in Regulation of Arteriovenous Gene Expression. Circ Res. 2020;126(7):875-88. Epub 2020/02/18. doi: 10.1161/CIRCRESAHA.119.316075. PubMed PMID: 32065070; PMCID: PMC7212523.   

Smith JL, Rodriguez TC, Mou H, Kwan SY, Pratt H, Zhang XO, Cao Y, Liang S, Ozata DM, Yu T, Yin Q, Hazeltine M, Weng Z, Sontheimer EJ, Xue W. YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte-like cells. Hepatology. 2020. Epub 2020/05/27. doi: 10.1002/hep.31389. PubMed PMID: 32452550.   

Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W. Adenine base editing in an adult mouse model of tyrosinaemia. Nat Biomed Eng. 2020;4(1):125-30. Epub 2019/11/20. doi: 10.1038/s41551-019-0357-8. PubMed PMID: 31740768; PMCID: PMC6986236.   

Stanney W, 3rd, Ladam F, Donaldson IJ, Parsons TJ, Maehr R, Bobola N, Sagerstrom CG. Combinatorial action of NF-Y and TALE at embryonic enhancers defines distinct gene expression programs during zygotic genome activation in zebrafish. Dev Biol. 2020;459(2):161-80. Epub 2019/12/22. doi: 10.1016/j.ydbio.2019.12.003. PubMed PMID: 31862379; PMCID: PMC7080602.   

Struck MW, Pazour GJ, Lambright DG. X Caps the Phosphate for Phospho-Rab GTPase Recognition in Ciliogenesis and Parkinson's Disease. Structure. 2020;28(4):385-7. Epub 2020/04/09. doi: 10.1016/j.str.2020.03.005. PubMed PMID: 32268075.   

Thielen LA, Chen J, Jing G, Moukha-Chafiq O, Xu G, Jo S, Grayson TB, Lu B, Li P, Augelli-Szafran CE, Suto MJ, Kanke M, Sethupathy P, Kim JK, Shalev A. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. Cell Metab. 2020;32(3):353-65 e8. Epub 2020/07/30. doi: 10.1016/j.cmet.2020.07.002. PubMed PMID: 32726606; PMCID: PMC7501995.   

Topal S, Van C, Xue Y, Carey MF, Peterson CL. INO80C Remodeler Maintains Genomic Stability by Preventing Promiscuous Transcription at Replication Origins. Cell Rep. 2020;32(10):108106. Epub 2020/09/10. doi: 10.1016/j.celrep.2020.108106. PubMed PMID: 32905765; PMCID: PMC7540730.   

Tran KV, Brown EL, DeSouza T, Jespersen NZ, Nandrup-Bus C, Yang Q, Yang Z, Desai A, Min SY, Rojas-Rodriguez R, Lundh M, Feizi A, Willenbrock H, Larsen TJ, Severinsen MCK, Malka K, Mozzicato AM, Deshmukh AS, Emanuelli B, Pedersen BK, Fitzgibbons T, Scheele C, Corvera S, Nielsen S. Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473. Nat Metab. 2020;2(5):397-412. Epub 2020/05/23. doi: 10.1038/s42255-020-0205-x. PubMed PMID: 32440655; PMCID: PMC7241442.   

Tran NT, Heiner C, Weber K, Weiand M, Wilmot D, Xie J, Wang D, Brown A, Manokaran S, Su Q, Zapp ML, Gao G, Tai PWL. AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Design-Influenced Heterogeneity. Mol Ther Methods Clin Dev. 2020;18:639-51. Epub 2020/08/11. doi: 10.1016/j.omtm.2020.07.007. PubMed PMID: 32775498; PMCID: PMC7397707.   

Tsuji J, Thomson T, Chan E, Brown CK, Oppenheimer J, Bigelow C, Dong X, Theurkauf WE, Weng Z, Schwartz LM. High-resolution analysis of differential gene expression during skeletal muscle atrophy and programmed cell death. Physiol Genomics. 2020;52(10):492-511. Epub 2020/09/15. doi: 10.1152/physiolgenomics.00047.2020. PubMed PMID: 32926651; PMCID: PMC7750511.   

Vangala P, Murphy R, Quinodoz SA, Gellatly K, McDonel P, Guttman M, Garber M. High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection. Mol Cell. 2020;80(2):359-73 e8. Epub 2020/09/30. doi: 10.1016/j.molcel.2020.09.005. PubMed PMID: 32991830; PMCID: PMC7572724.   

Vasquez-Rifo A, Ricci EP, Ambros V. Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes. PLoS Biol. 2020;18(12):e3000969. Epub 2020/12/02. doi: 10.1371/journal.pbio.3000969. PubMed PMID: 33259473; PMCID: PMC7707567.   

Vatsalya V, Cave MC, Kong M, Gobejishvili L, Falkner KC, Craycroft J, Mitchell M, Szabo G, McCullough A, Dasarathy S, Radaeva S, Barton B, McClain CJ. Keratin 18 Is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis. Clin Gastroenterol Hepatol. 2020;18(9):2046-54. Epub 2019/12/08. doi: 10.1016/j.cgh.2019.11.050. PubMed PMID: 31811953; PMCID: PMC7269867.   

Verity R, Aydemir O, Brazeau NF, Watson OJ, Hathaway NJ, Mwandagalirwa MK, Marsh PW, Thwai K, Fulton T, Denton M, Morgan AP, Parr JB, Tumwebaze PK, Conrad M, Rosenthal PJ, Ishengoma DS, Ngondi J, Gutman J, Mulenga M, Norris DE, Moss WJ, Mensah BA, Myers-Hansen JL, Ghansah A, Tshefu AK, Ghani AC, Meshnick SR, Bailey JA, Juliano JJ. The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC. Nat Commun. 2020;11(1):2107. Epub 2020/05/02. doi: 10.1038/s41467-020-15779-8. PubMed PMID: 32355199; PMCID: PMC7192906.   

Walker RG, Barrandon O, Poggioli T, Dagdeviren S, Carroll SH, Mills MJ, Mendello KR, Gomez Y, Loffredo FS, Pancoast JR, Macias-Trevino C, Marts C, LeClair KB, Noh HL, Kim T, Banks AS, Kim JK, Cohen DE, Wagers AJ, Melton DA, Lee RT. Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice. Sci Rep. 2020;10(1):4561. Epub 2020/03/14. doi: 10.1038/s41598-020-61443-y. PubMed PMID: 32165710; PMCID: PMC7067781.   

Wang A, Kolhe JA, Gioacchini N, Baade I, Brieher WM, Peterson CL, Freeman BC. Mechanism of Long-Range Chromosome Motion Triggered by Gene Activation. Dev Cell. 2020;52(3):309-20 e5. Epub 2020/01/07. doi: 10.1016/j.devcel.2019.12.007. PubMed PMID: 31902656; PMCID: PMC7108666.   

Wang G, Yu Y, Cai W, Batista TM, Suk S, Noh HL, Hirshman M, Nigro P, Li ME, Softic S, Goodyear L, Kim JK, Kahn CR. Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance. Diabetes. 2020;69(11):2294-309. Epub 2020/09/02. doi: 10.2337/db20-0439. PubMed PMID: 32868340; PMCID: PMC7576573.   

Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, Kucukural A, McDonel P, Hunt PW, Greenough T, Houghton J, Somsouk M, Estes JD, Brenchley JM, Garber M, Deeks SG, Luban J. HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells. Nat Immunol. 2020;21(3):274-86. Epub 2020/02/19. doi: 10.1038/s41590-020-0593-9. PubMed PMID: 32066947; PMCID: PMC7044076.   

Wang Z, Shi Y, Ma S, Huang Q, Yap YT, Shi L, Zhang S, Zhou T, Li W, Hu B, Zhang L, Krawetz SA, Pazour GJ, Hess RA, Zhang Z. Abnormal fertility, acrosome formation, IFT20 expression and localization in conditional Gmap210 knockout mice. Am J Physiol Cell Physiol. 2020;318(1):C174-C90. Epub 2019/10/03. doi: 10.1152/ajpcell.00517.2018. PubMed PMID: 31577511; PMCID: PMC6985835.   

Wu SS, Li QC, Yin CQ, Xue W, Song CQ. Advances in CRISPR/Cas-based Gene Therapy in Human Genetic Diseases. Theranostics. 2020;10(10):4374-82. Epub 2020/04/16. doi: 10.7150/thno.43360. PubMed PMID: 32292501; PMCID: PMC7150498.   

Ye C, Yang H, Cheng M, Shultz LD, Greiner DL, Brehm MA, Keck JG. A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome. FASEB J. 2020;34(9):12963-75. Epub 2020/08/11. doi: 10.1096/fj.202001203R. PubMed PMID: 32772418; PMCID: PMC7436391.   

Yilmaz LS, Li X, Nanda S, Fox B, Schroeder F, Walhout AJ. Modeling tissue-relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels. Mol Syst Biol. 2020;16(10):e9649. Epub 2020/10/07. doi: 10.15252/msb.20209649. PubMed PMID: 33022146; PMCID: PMC7537831.   

Yukselen O, Turkyilmaz O, Ozturk AR, Garber M, Kucukural A. DolphinNext: a distributed data processing platform for high throughput genomics. BMC Genomics. 2020;21(1):310. Epub 2020/04/21. doi: 10.1186/s12864-020-6714-x. PubMed PMID: 32306927; PMCID: PMC7168977.   

Yurkovetskiy L, Wang X, Pascal KE, Tomkins-Tinch C, Nyalile TP, Wang Y, Baum A, Diehl WE, Dauphin A, Carbone C, Veinotte K, Egri SB, Schaffner SF, Lemieux JE, Munro JB, Rafique A, Barve A, Sabeti PC, Kyratsous CA, Dudkina NV, Shen K, Luban J. Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. Cell. 2020;183(3):739-51 e8. Epub 2020/09/30. doi: 10.1016/j.cell.2020.09.032. PubMed PMID: 32991842; PMCID: PMC7492024.