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Publications 2015

Palma P, Foster C, Rojo P, Zangari P, Yates A, Cotugno N, Klein N, Luzuriaga K, Pahwa S, Nastouli E, Gibb DM, Borkowsky W, Bernardi S, Calvez V, Manno E, Mora N, Compagnucci A, Wahren B, Munoz-Fernandez M, De Rossi A, Ananworanich J, Pillay D, Giaquinto C, Rossi P. The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children. J Virus Erad. 2015;1(3):134-9. Epub 2016/02/20. PubMed PMID: 26893908; PMCID: PMC4755515.
https://www.ncbi.nlm.nih.gov/pubmed/26893908 

Sharma U, Conine CC, Shea JM, Boskovic A, Derr AG, Bing XY, Belleannee C, Kucukural A, Serra RW, Sun F, Song L, Carone BR, Ricci EP, Li XZ, Fauquier L, Moore MJ, Sullivan R, Mello CC, Garber M, Rando OJ. Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science. 2016;351(6271):391-6. Epub 2016/01/02. doi: 10.1126/science.aad6780. PubMed PMID: 26721685; PMCID: PMC4888079.
https://www.ncbi.nlm.nih.gov/pubmed/26721685 

Vivar OI, Masi G, Carpier JM, Magalhaes JG, Galgano D, Pazour GJ, Amigorena S, Hivroz C, Baldari CT. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113(2):386-91. Epub 2015/12/31. doi: 10.1073/pnas.1513601113. PubMed PMID: 26715756; PMCID: PMC4720349. https://www.ncbi.nlm.nih.gov/pubmed/26715756

Nayar R, Schutten E, Jangalwe S, Durost PA, Kenney LL, Conley JM, Daniels K, Brehm MA, Welsh RM, Berg LJ. IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection. PLoS One. 2015;10(12):e0144826. Epub 2015/12/30. doi: 10.1371/journal.pone.0144826. PubMed PMID: 26714260; PMCID: PMC4699851. https://www.ncbi.nlm.nih.gov/pubmed/26714260

Specht CA, Lee CK, Huang H, Tipper DJ, Shen ZT, Lodge JK, Leszyk J, Ostroff GR, Levitz SM. Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts. MBio. 2015;6(6):e01905-15. Epub 2015/12/24. doi: 10.1128/mBio.01905-15. PubMed PMID: 26695631; PMCID: PMC4701832.
https://www.ncbi.nlm.nih.gov/pubmed/26695631 

Roth Flach RJ, Skoura A, Matevossian A, Danai LV, Zheng W, Cortes C, Bhattacharya SK, Aouadi M, Hagan N, Yawe JC, Vangala P, Menendez LG, Cooper MP, Fitzgibbons TP, Buckbinder L, Czech MP. Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis. Nat Commun. 2015;6:8995. Epub 2015/12/22. doi: 10.1038/ncomms9995. PubMed PMID: 26688060; PMCID: PMC4703891.
https://www.ncbi.nlm.nih.gov/pubmed/26688060 

Sontheimer EJ, Wolfe SA. Cas9 gets a classmate. Nat Biotechnol. 2015;33(12):1240-1. Epub 2015/12/10. doi: 10.1038/nbt.3426. PubMed PMID: 26650011. https://www.ncbi.nlm.nih.gov/pubmed/26650011

Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance. FASEB J. 2016;30(3):1328-38. Epub 2015/12/09. doi: 10.1096/fj.15-280610. PubMed PMID: 26644351; PMCID: PMC4750424.
https://www.ncbi.nlm.nih.gov/pubmed/26644351 

Li Q, Ip YT. More Frequent than Desired: Midgut Stem Cell Somatic Mutations. Cell Stem Cell. 2015;17(6):639-40. Epub 2015/12/08. doi: 10.1016/j.stem.2015.11.011. PubMed PMID: 26637937.
https://www.ncbi.nlm.nih.gov/pubmed/26637937 

Caillat C, Macheboeuf P, Wu Y, McCarthy AA, Boeri-Erba E, Effantin G, Gottlinger HG, Weissenhorn W, Renesto P. Asymmetric ring structure of Vps4 required for ESCRT-III disassembly. Nat Commun. 2015;6:8781. Epub 2015/12/04. doi: 10.1038/ncomms9781. PubMed PMID: 26632262; PMCID: PMC4686814. https://www.ncbi.nlm.nih.gov/pubmed/26632262

Watson E, Yilmaz LS, Walhout AJ. Understanding Metabolic Regulation at a Systems Level: Metabolite Sensing, Mathematical Predictions, and Model Organisms. Annu Rev Genet. 2015;49:553-75. Epub 2015/12/04. doi: 10.1146/annurev-genet-112414-055257. PubMed PMID: 26631516.
https://www.ncbi.nlm.nih.gov/pubmed/26631516

Wu S, Bellve KD, Fogarty KE, Melikian HE. Ack1 is a dopamine transporter endocytic brake that rescues a trafficking-dysregulated ADHD coding variant. Proc Natl Acad Sci U S A. 2015;112(50):15480-5. Epub 2015/12/02. doi: 10.1073/pnas.1512957112. PubMed PMID: 26621748; PMCID: PMC4687542.
https://www.ncbi.nlm.nih.gov/pubmed/26621748 

Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, Jung DY, Lee Y, Kitamura T, Ergun S, Kulkarni RN, Kim JK, Giovannucci DR, Najjar SM. Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2). J Biol Chem. 2016;291(2):980-8. Epub 2015/11/21. doi: 10.1074/jbc.M115.692582. PubMed PMID: 26586918; PMCID: PMC4705415.
https://www.ncbi.nlm.nih.gov/pubmed/26586918 

Rege M, Subramanian V, Zhu C, Hsieh TH, Weiner A, Friedman N, Clauder-Munster S, Steinmetz LM, Rando OJ, Boyer LA, Peterson CL. Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis. Cell Rep. 2015;13(8):1610-22. Epub 2015/11/21. doi: 10.1016/j.celrep.2015.10.030. PubMed PMID: 26586442; PMCID: PMC4662874. https://www.ncbi.nlm.nih.gov/pubmed/26586442

Sanborn KB, Somasundaran M, Luzuriaga K, Leitner T. Recombination elevates the effective evolutionary rate and facilitates the establishment of HIV-1 infection in infants after mother-to-child transmission. Retrovirology. 2015;12:96. Epub 2015/11/18. doi: 10.1186/s12977-015-0222-0. PubMed PMID: 26573574; PMCID: PMC4647327.
https://www.ncbi.nlm.nih.gov/pubmed/26573574 

Sundberg JP, McElwee K, Brehm MA, Su L, King LE, Jr. Animal Models for Alopecia Areata: What and Where? J Investig Dermatol Symp Proc. 2015;17(2):23-6. Epub 2015/11/10. doi: 10.1038/jidsymp.2015.35. PubMed PMID: 26551940; PMCID: PMC4722955.
https://www.ncbi.nlm.nih.gov/pubmed/26551940 

Chen PB, Chen HV, Acharya D, Rando OJ, Fazzio TG. R loops regulate promoter-proximal chromatin architecture and cellular differentiation. Nat Struct Mol Biol. 2015;22(12):999-1007. Epub 2015/11/10. doi: 10.1038/nsmb.3122. PubMed PMID: 26551076; PMCID: PMC4677832.
https://www.ncbi.nlm.nih.gov/pubmed/26551076 

Jurczyk A, Nowosielska A, Przewozniak N, Aryee KE, DiIorio P, Blodgett D, Yang C, Campbell-Thompson M, Atkinson M, Shultz L, Rittenhouse A, Harlan D, Greiner D, Bortell R. Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic beta-cell function via glycogen synthase kinase-3beta. FASEB J. 2016;30(2):983-93. Epub 2015/11/08. doi: 10.1096/fj.15-279810. PubMed PMID: 26546129; PMCID: PMC4714549.
https://www.ncbi.nlm.nih.gov/pubmed/26546129 

Kahn RA, Lambright DG. A PH Domain with Dual Phospholipid Binding Sites Regulates the ARF GAP, ASAP1. Structure. 2015;23(11):1971-3. Epub 2015/11/05. doi: 10.1016/j.str.2015.10.002. PubMed PMID: 26536378.
https://www.ncbi.nlm.nih.gov/pubmed/26536378 

Genga RM, Kearns NA, Maehr R. Controlling transcription in human pluripotent stem cells using CRISPR-effectors. Methods. 2016;101:36-42. Epub 2015/11/04. doi: 10.1016/j.ymeth.2015.10.014. PubMed PMID: 26525193; PMCID: PMC4842159. https://www.ncbi.nlm.nih.gov/pubmed/26525193 

Zhang Y, Rajan R, Seifert HS, Mondragon A, Sontheimer EJ. DNase H Activity of Neisseria meningitidis Cas9. Mol Cell. 2015;60(2):242-55. Epub 2015/10/17. doi: 10.1016/j.molcel.2015.09.020. PubMed PMID: 26474066; PMCID: PMC4609032. https://www.ncbi.nlm.nih.gov/pubmed/26474066

Richter JD, Coller J. Pausing on Polyribosomes: Make Way for Elongation in Translational Control. Cell. 2015;163(2):292-300. Epub 2015/10/10. doi: 10.1016/j.cell.2015.09.041. PubMed PMID: 26451481; PMCID: PMC4600128.
https://www.ncbi.nlm.nih.gov/pubmed/26451481 

Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD, Frank J. Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res. 2015;43(21):10515-24. Epub 2015/10/04. doi: 10.1093/nar/gkv991. PubMed PMID: 26432834; PMCID: PMC4666399.
https://www.ncbi.nlm.nih.gov/pubmed/26432834 

Sewald X, Ladinsky MS, Uchil PD, Beloor J, Pi R, Herrmann C, Motamedi N, Murooka TT, Brehm MA, Greiner DL, Shultz LD, Mempel TR, Bjorkman PJ, Kumar P, Mothes W. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science. 2015;350(6260):563-7. Epub 2015/10/03. doi: 10.1126/science.aab2749. PubMed PMID: 26429886; PMCID: PMC4651917. https://www.ncbi.nlm.nih.gov/pubmed/26429886

San Agustin JT, Pazour GJ, Witman GB. Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm. Mol Biol Cell. 2015;26(24):4358-72. Epub 2015/10/02. doi: 10.1091/mbc.E15-08-0578. PubMed PMID: 26424803; PMCID: PMC4666132.
https://www.ncbi.nlm.nih.gov/pubmed/26424803

Rochford R, Moormann AM. Burkitt's Lymphoma. Curr Top Microbiol Immunol. 2015;390(Pt 1):267-85. Epub 2015/10/02. doi: 10.1007/978-3-319-22822-8_11. PubMed PMID: 26424650.
https://www.ncbi.nlm.nih.gov/pubmed/26424650

Rosa A, Chande A, Ziglio S, De Sanctis V, Bertorelli R, Goh SL, McCauley SM, Nowosielska A, Antonarakis SE, Luban J, Santoni FA, Pizzato M. HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation. Nature. 2015;526(7572):212-7. Epub 2015/09/30. doi: 10.1038/nature15399. PubMed PMID: 26416734; PMCID: PMC4861059.
https://www.ncbi.nlm.nih.gov/pubmed/26416734

Greenough TC, Straubhaar JR, Kamga L, Weiss ER, Brody RM, McManus MM, Lambrecht LK, Somasundaran M, Luzuriaga KF. A Gene Expression Signature That Correlates with CD8+ T Cell Expansion in Acute EBV Infection. J Immunol. 2015;195(9):4185-97. Epub 2015/09/30. doi: 10.4049/jimmunol.1401513. PubMed PMID: 26416268; PMCID: PMC4610856.
https://www.ncbi.nlm.nih.gov/pubmed/26416268

Bilbao A, Zhang Y, Varesio E, Luban J, Strambio-De-Castillia C, Lisacek F, Hopfgartner G. Ranking Fragment Ions Based on Outlier Detection for Improved Label-Free Quantification in Data-Independent Acquisition LC-MS/MS. J Proteome Res. 2015;14(11):4581-93. Epub 2015/09/29. doi: 10.1021/acs.jproteome.5b00394. PubMed PMID: 26412574; PMCID: PMC4739871. https://www.ncbi.nlm.nih.gov/pubmed/26412574

Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, Richter JD. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene. 2016;35(22):2893-901. Epub 2015/09/29. doi: 10.1038/onc.2015.350. PubMed PMID: 26411364; PMCID: PMC4809797.
https://www.ncbi.nlm.nih.gov/pubmed/26411364

Li S, Ling C, Zhong L, Li M, Su Q, He R, Tang Q, Greiner DL, Shultz LD, Brehm MA, Flotte TR, Mueller C, Srivastava A, Gao G. Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors. Mol Ther. 2015;23(12):1867-76. Epub 2015/09/26. doi: 10.1038/mt.2015.174. PubMed PMID: 26403887; PMCID: PMC4700112.
https://www.ncbi.nlm.nih.gov/pubmed/26403887

De Jesus M, Rodriguez AE, Yagita H, Ostroff GR, Mantis NJ. Sampling of Candida albicans and Candida tropicalis by Langerin-positive dendritic cells in mouse Peyer's patches. Immunol Lett. 2015;168(1):64-72. Epub 2015/09/20. doi: 10.1016/j.imlet.2015.09.008. PubMed PMID: 26386376.
https://www.ncbi.nlm.nih.gov/pubmed/26386376

Hung HF, Hehnly H, Doxsey S. Methods to analyze novel liaisons between endosomes and centrosomes. Methods Cell Biol. 2015;130:47-58. Epub 2015/09/12. doi: 10.1016/bs.mcb.2015.03.024. PubMed PMID: 26360027.
https://www.ncbi.nlm.nih.gov/pubmed/26360027

Vertii A, Bright A, Delaval B, Hehnly H, Doxsey S. New frontiers: discovering cilia-independent functions of cilia proteins. EMBO Rep. 2015;16(10):1275-87. Epub 2015/09/12. doi: 10.15252/embr.201540632. PubMed PMID: 26358956; PMCID: PMC4766453. https://www.ncbi.nlm.nih.gov/pubmed/26358956

Zinovyeva AY, Veksler-Lublinsky I, Vashisht AA, Wohlschlegel JA, Ambros VR. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Proc Natl Acad Sci U S A. 2015;112(38):E5271-80. Epub 2015/09/10. doi: 10.1073/pnas.1506576112. PubMed PMID: 26351692; PMCID: PMC4586838. https://www.ncbi.nlm.nih.gov/pubmed/26351692

Richter JD, Bassell GJ, Klann E. Dysregulation and restoration of translational homeostasis in fragile X syndrome. Nat Rev Neurosci. 2015;16(10):595-605. Epub 2015/09/10. doi: 10.1038/nrn4001. PubMed PMID: 26350240; PMCID: PMC4688896. https://www.ncbi.nlm.nih.gov/pubmed/26350240

Nie Y, Li Q, Amcheslavsky A, Duhart JC, Veraksa A, Stocker H, Raftery LA, Ip YT. Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila. Stem Cell Rev. 2015;11(6):813-25. Epub 2015/09/02. doi: 10.1007/s12015-015-9617-5. PubMed PMID: 26323255; PMCID: PMC4653243.
https://www.ncbi.nlm.nih.gov/pubmed/26323255

Yang C, Loehn M, Jurczyk A, Przewozniak N, Leehy L, Herrera PL, Shultz LD, Greiner DL, Harlan DM, Bortell R. Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets. Diabetes Metab Syndr Obes. 2015;8:387-98. Epub 2015/09/01. doi: 10.2147/DMSO.S87253. PubMed PMID: 26316789; PMCID: PMC4548726.
https://www.ncbi.nlm.nih.gov/pubmed/26316789

Malaby AW, Chakravarthy S, Irving TC, Kathuria SV, Bilsel O, Lambright DG. Methods for analysis of size-exclusion chromatography-small-angle X-ray scattering and reconstruction of protein scattering. J Appl Crystallogr. 2015;48(Pt 4):1102-13. Epub 2015/08/26. doi: 10.1107/S1600576715010420. PubMed PMID: 26306089; PMCID: PMC4520288.
https://www.ncbi.nlm.nih.gov/pubmed/26306089 

Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV. The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. J Immunol. 2015;195(7):3011-9. Epub 2015/08/19. doi: 10.4049/jimmunol.1402446. PubMed PMID: 26283479; PMCID: PMC4575869.
https://www.ncbi.nlm.nih.gov/pubmed/26283479

Vertii A, Zimmerman W, Ivshina M, Doxsey S. Centrosome-intrinsic mechanisms modulate centrosome integrity during fever. Mol Biol Cell. 2015;26(19):3451-63. Epub 2015/08/14. doi: 10.1091/mbc.E15-03-0158. PubMed PMID: 26269579; PMCID: PMC4591690.
https://www.ncbi.nlm.nih.gov/pubmed/26269579

Roth Flach RJ, Czech MP. NETs and traps delay wound healing in diabetes. Trends Endocrinol Metab. 2015;26(9):451-2. Epub 2015/08/05. doi: 10.1016/j.tem.2015.07.004. PubMed PMID: 26239304; PMCID: PMC4558202.
https://www.ncbi.nlm.nih.gov/pubmed/26239304

Klein N, Palma P, Luzuriaga K, Pahwa S, Nastouli E, Gibb DM, Rojo P, Borkowsky W, Bernardi S, Zangari P, Calvez V, Compagnucci A, Wahren B, Foster C, Munoz-Fernandez MA, De Rossi A, Ananworanich J, Pillay D, Giaquinto C, Rossi P. Early antiretroviral therapy in children perinatally infected with HIV: a unique opportunity to implement immunotherapeutic approaches to prolong viral remission. Lancet Infect Dis. 2015;15(9):1108-14. Epub 2015/07/19. doi: 10.1016/S1473-3099(15)00052-3. PubMed PMID: 26187030.
https://www.ncbi.nlm.nih.gov/pubmed/26187030

Pizzato M, McCauley SM, Neagu MR, Pertel T, Firrito C, Ziglio S, Dauphin A, Zufferey M, Berthoux L, Luban J. Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration. PLoS Pathog. 2015;11(7):e1005050. Epub 2015/07/17. doi: 10.1371/journal.ppat.1005050. PubMed PMID: 26181333; PMCID: PMC4504712. https://www.ncbi.nlm.nih.gov/pubmed/26181333

Pedersen DJ, Guilherme A, Danai LV, Heyda L, Matevossian A, Cohen J, Nicoloro SM, Straubhaar J, Noh HL, Jung D, Kim JK, Czech MP. A major role of insulin in promoting obesity-associated adipose tissue inflammation. Mol Metab. 2015;4(7):507-18. Epub 2015/07/03. doi: 10.1016/j.molmet.2015.04.003. PubMed PMID: 26137438; PMCID: PMC4481426.
https://www.ncbi.nlm.nih.gov/pubmed/26137438

Tissenbaum HA. Using C. elegans for aging research. Invertebr Reprod Dev. 2015;59(sup1):59-63. Epub 2015/07/03. doi: 10.1080/07924259.2014.940470. PubMed PMID: 26136622; PMCID: PMC4464094. https://www.ncbi.nlm.nih.gov/pubmed/26136622

Matar CG, Jacobs NT, Speck SH, Lamb TJ, Moormann AM. Does EBV alter the pathogenesis of malaria? Parasite Immunol. 2015;37(9):433-45. Epub 2015/06/30. doi: 10.1111/pim.12212. PubMed PMID: 26121587.
https://www.ncbi.nlm.nih.gov/pubmed/26121587

Hu YJ, Belaghzal H, Hsiao WY, Qi J, Bradner JE, Guertin DA, Sif S, Imbalzano AN. Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6. Nucleic Acids Res. 2015;43(16):7790-804. Epub 2015/06/29. doi: 10.1093/nar/gkv645. PubMed PMID: 26117538; PMCID: PMC4652747.
https://www.ncbi.nlm.nih.gov/pubmed/26117538 

Elewa A, Shirayama M, Kaymak E, Harrison PF, Powell DR, Du Z, Chute CD, Woolf H, Yi D, Ishidate T, Srinivasan J, Bao Z, Beilharz TH, Ryder SP, Mello CC. POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA. Dev Cell. 2015;34(1):108-18. Epub 2015/06/23. doi: 10.1016/j.devcel.2015.05.024. PubMed PMID: 26096734; PMCID: PMC4507413. https://www.ncbi.nlm.nih.gov/pubmed/26096734

Burke SL, Hammell M, Ambros V. Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans. Genetics. 2015;200(4):1201-18. Epub 2015/06/17. doi: 10.1534/genetics.115.179184. PubMed PMID: 26078280; PMCID: PMC4574240. https://www.ncbi.nlm.nih.gov/pubmed/26078280

Sontheimer EJ, Barrangou R. The Bacterial Origins of the CRISPR Genome-Editing Revolution. Hum Gene Ther. 2015;26(7):413-24. Epub 2015/06/17. doi: 10.1089/hum.2015.091. PubMed PMID: 26078042.
https://www.ncbi.nlm.nih.gov/pubmed/26078042

Iyengar S, Kasheta M, Ceol CJ. Poised Regeneration of Zebrafish Melanocytes Involves Direct Differentiation and Concurrent Replenishment of Tissue-Resident Progenitor Cells. Dev Cell. 2015;33(6):631-43. Epub 2015/06/16. doi: 10.1016/j.devcel.2015.04.025. PubMed PMID: 26073020; PMCID: PMC4480189. https://www.ncbi.nlm.nih.gov/pubmed/26073020

Rojas-Rodriguez R, Lifshitz LM, Bellve KD, Min SY, Pires J, Leung K, Boeras C, Sert A, Draper JT, Corvera S, Moore Simas TA. Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus. Diabetologia. 2015;58(9):2106-14. Epub 2015/06/13. doi: 10.1007/s00125-015-3662-0. PubMed PMID: 26067361; PMCID: PMC4526585.
https://www.ncbi.nlm.nih.gov/pubmed/26067361

Peters PJ, Gonzalez-Perez MP, Musich T, Moore Simas TA, Lin R, Morse AN, Shattock RJ, Derdeyn CA, Clapham PR. Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes. Retrovirology. 2015;12:48. Epub 2015/06/10. doi: 10.1186/s12977-015-0176-2. PubMed PMID: 26055104; PMCID: PMC4459458. https://www.ncbi.nlm.nih.gov/pubmed/26055104

Finetti F, Patrussi L, Galgano D, Cassioli C, Perinetti G, Pazour GJ, Baldari CT. The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse. J Cell Sci. 2015;128(14):2541-52. Epub 2015/06/03. doi: 10.1242/jcs.171652. PubMed PMID: 26034069; PMCID: PMC4510855.
https://www.ncbi.nlm.nih.gov/pubmed/26034069

Yang N, Li L, Eguether T, Sundberg JP, Pazour GJ, Chen J. Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis. Development. 2015;142(12):2194-202. Epub 2015/05/30. doi: 10.1242/dev.115261. PubMed PMID: 26023097; PMCID: PMC4483764. https://www.ncbi.nlm.nih.gov/pubmed/26023097

Margevicius DR, Bastian C, Fan Q, Davis RJ, Pimplikar SW. JNK-interacting protein 1 mediates Alzheimer's-like pathological features in AICD-transgenic mice. Neurobiol Aging. 2015;36(8):2370-9. Epub 2015/05/30. doi: 10.1016/j.neurobiolaging.2015.04.013. PubMed PMID: 26022769.
https://www.ncbi.nlm.nih.gov/pubmed/26022769

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Veiseh O, Doloff JC, Ma M, Vegas AJ, Tam HH, Bader AR, Li J, Langan E, Wyckoff J, Loo WS, Jhunjhunwala S, Chiu A, Siebert S, Tang K, Hollister-Lock J, Aresta-Dasilva S, Bochenek M, Mendoza-Elias J, Wang Y, Qi M, Lavin DM, Chen M, Dholakia N, Thakrar R, Lacik I, Weir GC, Oberholzer J, Greiner DL, Langer R, Anderson DG. Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates. Nat Mater. 2015;14(6):643-51. Epub 2015/05/20. doi: 10.1038/nmat4290. PubMed PMID: 25985456; PMCID: PMC4477281.
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Zhang Y, Bottinelli D, Lisacek F, Luban J, Strambio-De-Castillia C, Varesio E, Hopfgartner G. Optimization of human dendritic cell sample preparation for mass spectrometry-based proteomic studies. Anal Biochem. 2015;484:40-50. Epub 2015/05/20. doi: 10.1016/j.ab.2015.05.007. PubMed PMID: 25983236; PMCID: PMC4732721. https://www.ncbi.nlm.nih.gov/pubmed/25983236

Samanta S, Sun H, Goel HL, Pursell B, Chang C, Khan A, Greiner DL, Cao S, Lim E, Shultz LD, Mercurio AM. IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG. Oncogene. 2016;35(9):1111-21. Epub 2015/05/20. doi: 10.1038/onc.2015.164. PubMed PMID: 25982283; PMCID: PMC5784260. https://www.ncbi.nlm.nih.gov/pubmed/25982283

Al-Share QY, DeAngelis AM, Lester SG, Bowman TA, Ramakrishnan SK, Abdallah SL, Russo L, Patel PR, Kaw MK, Raphael CK, Kim AJ, Heinrich G, Lee AD, Kim JK, Kulkarni RN, Philbrick WM, Najjar SM. Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance. Diabetes. 2015;64(8):2780-90. Epub 2015/05/15. doi: 10.2337/db14-1772. PubMed PMID: 25972571; PMCID: PMC4512217. https://www.ncbi.nlm.nih.gov/pubmed/25972571

Watanabe S, Tan D, Lakshminarasimhan M, Washburn MP, Hong EJ, Walz T, Peterson CL. Structural analyses of the chromatin remodelling enzymes INO80-C and SWR-C. Nat Commun. 2015;6:7108. Epub 2015/05/13. doi: 10.1038/ncomms8108. PubMed PMID: 25964121; PMCID: PMC4431590.
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Jeronimo C, Watanabe S, Kaplan CD, Peterson CL, Robert F. The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations. Mol Cell. 2015;58(6):1113-23. Epub 2015/05/12. doi: 10.1016/j.molcel.2015.03.030. PubMed PMID: 25959393; PMCID: PMC4475440.
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Blodgett DM, Nowosielska A, Afik S, Pechhold S, Cura AJ, Kennedy NJ, Kim S, Kucukural A, Davis RJ, Kent SC, Greiner DL, Garber MG, Harlan DM, diIorio P. Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets. Diabetes. 2015;64(9):3172-81. Epub 2015/05/02. doi: 10.2337/db15-0039. PubMed PMID: 25931473; PMCID: PMC4542439. https://www.ncbi.nlm.nih.gov/pubmed/25931473

Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovacs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabasi AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 2015;161(3):647-60. Epub 2015/04/25. doi: 10.1016/j.cell.2015.04.013. PubMed PMID: 25910212; PMCID: PMC4441215.
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Ren Z, Ambros VR. Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proc Natl Acad Sci U S A. 2015;112(18):E2366-75. Epub 2015/04/22. doi: 10.1073/pnas.1422858112. PubMed PMID: 25897023; PMCID: PMC4426397. https://www.ncbi.nlm.nih.gov/pubmed/25897023

Lee E, Jung DY, Kim JH, Patel PR, Hu X, Lee Y, Azuma Y, Wang HF, Tsitsilianos N, Shafiq U, Kwon JY, Lee HJ, Lee KW, Kim JK. Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance. FASEB J. 2015;29(8):3182-92. Epub 2015/04/19. doi: 10.1096/fj.14-268300. PubMed PMID: 25888600; PMCID: PMC4511197.
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Moore Simas TA, Corvera S, Lee MM, Zhang N, Leung K, Olendzki B, Barton B, Rosal MC. Understanding multifactorial influences on the continuum of maternal weight trajectories in pregnancy and early postpartum: study protocol, and participant baseline characteristics. BMC Pregnancy Childbirth. 2015;15:71. Epub 2015/04/18. doi: 10.1186/s12884-015-0490-7. PubMed PMID: 25885002; PMCID: PMC4389494.
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Damerla RR, Cui C, Gabriel GC, Liu X, Craige B, Gibbs BC, Francis R, Li Y, Chatterjee B, San Agustin JT, Eguether T, Subramanian R, Witman GB, Michaud JL, Pazour GJ, Lo CW. Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies. Hum Mol Genet. 2015;24(14):3994-4005. Epub 2015/04/17. doi: 10.1093/hmg/ddv137. PubMed PMID: 25877302; PMCID: PMC4476446.
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Bennett G, Peterson CL. SWI/SNF recruitment to a DNA double-strand break by the NuA4 and Gcn5 histone acetyltransferases. DNA Repair (Amst). 2015;30:38-45. Epub 2015/04/15. doi: 10.1016/j.dnarep.2015.03.006. PubMed PMID: 25869823; PMCID: PMC4425604.
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Mak P, Li J, Samanta S, Chang C, Jerry DJ, Davis RJ, Leav I, Mercurio AM. Prostate tumorigenesis induced by PTEN deletion involves estrogen receptor beta repression. Cell Rep. 2015;10(12):1982-91. Epub 2015/03/31. doi: 10.1016/j.celrep.2015.02.063. PubMed PMID: 25818291; PMCID: PMC4382442. https://www.ncbi.nlm.nih.gov/pubmed/25818291

Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW. Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015;521(7553):520-4. Epub 2015/03/26. doi: 10.1038/nature14269. PubMed PMID: 25807483; PMCID: PMC4617540.
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Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP. Activated Kupffer cells inhibit insulin sensitivity in obese mice. FASEB J. 2015;29(7):2959-69. Epub 2015/03/26. doi: 10.1096/fj.15-270496. PubMed PMID: 25805830; PMCID: PMC4478794.
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Sanchez-Gurmaches J, Hsiao WY, Guertin DA. Highly selective in vivo labeling of subcutaneous white adipocyte precursors with Prx1-Cre. Stem Cell Reports. 2015;4(4):541-50. Epub 2015/03/25. doi: 10.1016/j.stemcr.2015.02.008. PubMed PMID: 25801508; PMCID: PMC4400610.
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Mishra AK, Lambright DG. High-throughput assay for profiling the substrate specificity of Rab GTPase-activating proteins. Methods Mol Biol. 2015;1298:47-60. Epub 2015/03/25. doi: 10.1007/978-1-4939-2569-8_4. PubMed PMID: 25800831. https://www.ncbi.nlm.nih.gov/pubmed/25800831

Richter JD. RNA and the synapse. RNA. 2015;21(4):716-7. Epub 2015/03/18. doi: 10.1261/rna.050229.115. PubMed PMID: 25780206; PMCID: PMC4371348.
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Sontheimer E. Accelerating expansion. RNA. 2015;21(4):510. Epub 2015/03/18. doi: 10.1261/rna.050682.115. PubMed PMID: 25780117; PMCID: PMC4371259. https://www.ncbi.nlm.nih.gov/pubmed/25780117

Kearns NA, Pham H, Tabak B, Genga RM, Silverstein NJ, Garber M, Maehr R. Functional annotation of native enhancers with a Cas9-histone demethylase fusion. Nat Methods. 2015;12(5):401-3. Epub 2015/03/17. doi: 10.1038/nmeth.3325. PubMed PMID: 25775043; PMCID: PMC4414811.
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Lee MJ. Let a hundred flowers bloom: the role of context dependence in creating phenotypic diversity following targeted therapy. Mol Cell. 2015;57(5):763-4. Epub 2015/03/10. doi: 10.1016/j.molcel.2015.02.030. PubMed PMID: 25747655. https://www.ncbi.nlm.nih.gov/pubmed/25747655

Hainer SJ, Gu W, Carone BR, Landry BD, Rando OJ, Mello CC, Fazzio TG. Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF. Genes Dev. 2015;29(4):362-78. Epub 2015/02/19. doi: 10.1101/gad.253534.114. PubMed PMID: 25691467; PMCID: PMC4335293.
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Xue Y, Van C, Pradhan SK, Su T, Gehrke J, Kuryan BG, Kitada T, Vashisht A, Tran N, Wohlschlegel J, Peterson CL, Kurdistani SK, Carey MF. The Ino80 complex prevents invasion of euchromatin into silent chromatin. Genes Dev. 2015;29(4):350-5. Epub 2015/02/19. doi: 10.1101/gad.256255.114. PubMed PMID: 25691465; PMCID: PMC4335291.
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Perry RJ, Camporez JG, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI. Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell. 2015;160(4):745-58. Epub 2015/02/11. doi: 10.1016/j.cell.2015.01.012. PubMed PMID: 25662011; PMCID: PMC4498261.
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Rohatgi RA, Janusis J, Leonard D, Bellve KD, Fogarty KE, Baehrecke EH, Corvera S, Shaw LM. Beclin 1 regulates growth factor receptor signaling in breast cancer. Oncogene. 2015;34(42):5352-62. Epub 2015/02/03. doi: 10.1038/onc.2014.454. PubMed PMID: 25639875; PMCID: PMC4522409.
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May-Simera HL, Petralia RS, Montcouquiol M, Wang YX, Szarama KB, Liu Y, Lin W, Deans MR, Pazour GJ, Kelley MW. Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea. Development. 2015;142(3):555-66. Epub 2015/01/22. doi: 10.1242/dev.113696. PubMed PMID: 25605782; PMCID: PMC4302998. https://www.ncbi.nlm.nih.gov/pubmed/25605782

Gao M, Thomson TC, Creed TM, Tu S, Loganathan SN, Jackson CA, McCluskey P, Lin Y, Collier SE, Weng Z, Lasko P, Ohi MD, Arkov AL. Glycolytic enzymes localize to ribonucleoprotein granules in Drosophila germ cells, bind Tudor and protect from transposable elements. EMBO Rep. 2015;16(3):379-86. Epub 2015/01/21. doi: 10.15252/embr.201439694. PubMed PMID: 25600116; PMCID: PMC4364877. https://www.ncbi.nlm.nih.gov/pubmed/25600116

Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV. ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nat Commun. 2015;6:6023. Epub 2015/01/21. doi: 10.1038/ncomms7023. PubMed PMID: 25599650; PMCID: PMC4361001.
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Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, Ingerpuu S, Patarroyo M, Cao S, Lim E, Mao J, McKee KK, Yurchenco PD, Mercurio AM. A laminin 511 matrix is regulated by TAZ and functions as the ligand for the alpha6Bbeta1 integrin to sustain breast cancer stem cells. Genes Dev. 2015;29(1):1-6. Epub 2015/01/07. doi: 10.1101/gad.253682.114. PubMed PMID: 25561492; PMCID: PMC4281560.
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Li S, Cho YS, Yue T, Ip YT, Jiang J. Overlapping functions of the MAP4K family kinases Hppy and Msn in Hippo signaling. Cell Discov. 2015;1:15038. Epub 2015/01/01. doi: 10.1038/celldisc.2015.38. PubMed PMID: 27462435; PMCID: PMC4860773. https://www.ncbi.nlm.nih.gov/pubmed/27462435

Van C, Williams JS, Kunkel TA, Peterson CL. Deposition of histone H2A.Z by the SWR-C remodeling enzyme prevents genome instability. DNA Repair (Amst). 2015;25:9-14. Epub 2014/12/03. doi: 10.1016/j.dnarep.2014.10.010. PubMed PMID: 25463393; PMCID: PMC4276476.
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Ivshina M, Alexandrov IM, Vertii A, Doxsey S, Richter JD. CPEB regulation of TAK1 synthesis mediates cytokine production and the inflammatory immune response. Mol Cell Biol. 2015;35(3):610-8. Epub 2014/12/03. doi: 10.1128/MCB.00800-14. PubMed PMID: 25452303; PMCID: PMC4285422.
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Gallagher GR, Brehm MA, Finberg RW, Barton BA, Shultz LD, Greiner DL, Bortell R, Wang JP. Viral infection of engrafted human islets leads to diabetes. Diabetes. 2015;64(4):1358-69. Epub 2014/11/14. doi: 10.2337/db14-1020. PubMed PMID: 25392246; PMCID: PMC4375078.
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Armata HL, Chamberland S, Watts L, Ko HJ, Lee Y, Jung DY, Kim JK, Sluss HK. Deficiency of the tumor promoter gene wip1 induces insulin resistance. Mol Endocrinol. 2015;29(1):28-39. Epub 2014/11/08. doi: 10.1210/me.2014-1136. PubMed PMID: 25379953; PMCID: PMC4280527.
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Jaiswal S, Smith K, Ramirez A, Woda M, Pazoles P, Shultz LD, Greiner DL, Brehm MA, Mathew A. Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice. Exp Biol Med (Maywood). 2015;240(1):67-78. Epub 2014/08/16. doi: 10.1177/1535370214546273. PubMed PMID: 25125497; PMCID: PMC4446989.
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Sterling CH, Veksler-Lublinsky I, Ambros V. An efficient and sensitive method for preparing cDNA libraries from scarce biological samples. Nucleic Acids Res. 2015;43(1):e1. Epub 2014/07/25. doi: 10.1093/nar/gku637. PubMed PMID: 25056322; PMCID: PMC4288208.
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Trabucco SE, Gerstein RM, Evens AM, Bradner JE, Shultz LD, Greiner DL, Zhang H. Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma. Clin Cancer Res. 2015;21(1):113-22. Epub 2014/07/11. doi: 10.1158/1078-0432.CCR-13-3346. PubMed PMID: 25009295; PMCID: PMC4286476. https://www.ncbi.nlm.nih.gov/pubmed/25009295

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