Principal Investigator
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Victor Ambros, PhD
Principal Investigator
Silverman Professor of Natural Sciences
Program in Molecular Medicine
victor.ambros@umassmed.edu
(508) 856-5723
Ambros CVVictor Ambros did his graduate research (1976-1979) with David Baltimore at MIT, studying poliovirus genome structure and replication. He began to study the genetic pathways controlling developmental timing in the nematode C. elegans as a postdoc in H. Robert Horvitz’s lab at MIT, and continued those studies while on the faculty of Harvard (1984-1992), Dartmouth (1992-2007), and the UMass Chan Medical School (2008-present). In 1993, members of the Ambros lab identified the first microRNA, the product of lin-4, a heterochronic gene of C. elegans. Since then, the role of microRNAs in development has been a major focus of his research.