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Publications using SCOPE services

Published papers containing data collected on SCOPE microscopes from 2014-2020:

  1. Ly S, Echeverria D, Sousa J, Khvorova A. Single-stranded phosphorothioated regions enhance cellular internalization of cholesterol-conjugated siRNA but not silencing efficacy. Mol Ther Nuc Acids. Epub 2020 July 25. https://doi.org/10.1016/j.omtn.2020.07.029.
  2. Palace SG, Vitseva O, Proulx MK, Freedman JE, Goguen JD, and Koupenova M. Yersinia pestis Escapes Entrapment in Thrombi by Targeting Platelet Function. Thromb. Haemost July 24th 2020 (accepted). 
  3. Fu G, Zhao L, Dymek E, Hou Y, Song K, Phan N, Shang Z, Smith EF, Witman GB, Nicastro D. Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus. J Cell Biol. 2019 Dec 2;218(12):4236-4251. doi: 10.1083/jcb.201906006. Epub 2019 Oct 31. PMCID: PMC6891083 DOI: 1083/jcb.201906006
  4. Koupenova M, Mick E, Corkrey HA, Singh A, Tanriverdi SE, Vitseva O, Levy D, Keeler AM, Ezzaty Mirhashemi M, ElMallah MK, Gerstein M, Rozowsky J, Tanriverdi K, Freedman JE*. Pollen Derived miRNAs are found in the Human Circulation iScience 2019 Sep 27; 19:916-926. PMCID: PMC6742912  DOI: 1016/j.isci.2019.08.035
  5. Zhao L, Hou Y, Picariello T, Craige B, Witman GB. Proteome of the central apparatus of a ciliary axoneme. J Cell Biol. 2019 Jun 3;218(6):2051-2070. doi: 10.1083/jcb.201902017. Epub 2019 May 15. PMCID: PMC6548120   DOI: 1083/jcb.201902017
  6. Picariello T, Brown JM, Hou Y, Swank G, Cochran DA, King OD, Lechtreck K, Pazour GJ, Witman GB. A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia. J Cell Sci. 2019 Feb 11;132(3):jcs220749. PMCID: PMC6382014 DOI: 1242/jcs.220749
  7. Koupenova M, Corkrey HA, Vitseva O, Manni G, Clancy L, Pang CJ, Yao C, Rade J, Levy D, Wang JP, Finberg RW, Kurt-Jones EA, Freedman JE. The Role of Platelets in Mediating a Response to Human Influenza Infection. Nat Comm 2019, 10(1):1780 PMCID: PMCID: PMC6467905  DOI: 1038/s41467-019-09607-x
  8. Pickering M, Hollis LN, D'Souza E, Rhind N. Fission yeast cells grow approximately exponentially. Cell Cycle. 2019;18(8):869-879. PMCID: PMC6527286 DOI: 1080/15384101.2019.1595874
  9. E X, Meraner P, Lu P, Perreira JM, Aker AM, McDougall WM, Zhuge R, Chan GC, Gerstein RM, Caposio P, Yurochko AD, Brass AL, Kowalik TF. OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7043-7052. Epub 2019 Mar 20. PMCID: PMC6452726 DOI: 1073/pnas.1814850116
  10. McDougall WM, Perreira JM, Hung HF, Vertii A, Xiaofei E, Zimmerman W, Kowalik TF, Doxsey S, Brass AL. Viral Infection or IFN-α Alters Mitotic Spindle Orientation by Modulating Pericentrin Levels. 2019 Feb 22;12:270-279. Epub 2019 Jan 21. PMCID: PMC6360249 DOI: 10.1016/j.isci.2019.01.025
  11. Achuthan V, Perreira J M, Sowd G A, Puray-Chavez M, McDougall WM, Paulucci-Holthauzen A, Wu X, Fadel HJ, Poeschla EM, Multani AS, Hughes SH, Sarafianos SG, Brass AL, Engelman AN. Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. Cell Host Microbe. 2018;24(3):392-404.e8. PMCID: PMC6368089 DOI: 1016/j.chom.2018.08.002
  12. Ly S, Navaroli DM, Didiot MC, Cardia J, Pandarinathan L, Alterman JF, Fogarty K, Standley C, Lifshitz LM, Bellve KD, Prot M, Echeverria D, Corvera S, Khvorova A. Visualization of self-delivering hydrophobically modified siRNA cellular internalization. Nucleic Acids Res. 2017;45(1):15-25. PMCID: PMC5224471 DOI: 1093/nar/gkw1005
  13. Keifenheim, D., Sun, X. M., D'Souza, E., Ohira, M. J., Magner, M., Mayhew, M. B., Marguerat, S., & Rhind, N. Size-Dependent Expression of the Mitotic Activator Cdc25 Suggests a Mechanism of Size Control in Fission Yeast. Curr Biol. 2017;27(10):1491-1497.e4. doi:10.1016/j.cub.2017.04.016PMCID: PMC5479637 DOI: 1016/j.cub.2017.04.016
  14. Savidis G, Perreira JM, Portmann JM, Meraner P, Guo Z, Green S, Brass AL. The IFITMs Inhibit Zika Virus Replication. Cell Rep. 2016;15(11):2323-2330. PMID: 27268505 DOI: 1016/j.celrep.2016.05.074
  15. Savidis G, McDougall WM, Meraner P, Perreira JM, Portmann JM, Trincucci G, John SP, Aker AM, Renzette N, Robbins DR, Guo Z, Green S, Kowalik TF, Brass AL. Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. Cell Rep. 2016;16(1):232-246. PMID: 27342126 DOI: 1016/j.celrep.2016.06.028
  16. Perreira JM, Aker AM, Savidis G, Chin CR, McDougall WM, Portmann JM, Meraner P, Smith MC, Rahman M, Baker RE, Gauthier A, Franti M, Brass AL. RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus. Cell Rep. 2015;12(5):850-863. PMID: 26212330 DOI: 1016/j.celrep.2015.06.076
  17. Chin CR, Perreira JM, Savidis G, et al. Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration. Cell Rep. 2015;13(8):1717-1731. PMCID: PMC5026322 DOI: 1016/j.celrep.2015.10.036
  18. Brown JM, Cochran DA, Craige B, Kubo T, Witman GB. Assembly of IFT trains at the ciliary base depends on IFT74. Curr Biol. 2015 Jun 15;25(12):1583-93. Epub 2015 Jun 4. PMCID: PMC4482480 DOI: 1016/j.cub.2015.04.060
  19. Zhu J, Davoli T, Perriera, J. M., Chin, C. R., Gaiha, G. D., John, S. P., Sigiollot, F. D., Gao, G., Xu, Q., Qu, H., Pertel, T., Sims, J. S., Smith, J. A., Baker, R. E., Maranda, L., Ng, A., Elledge, S. J., & Brass, A. L. Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents. Cell Rep. 2014;9(2):752-766. PMCID: PMC4926641   DOI: 1016/j.celrep.2014.09.031

The SCOPE existed as a shared department resource in the Sanderson lab prior to 2018, papers published from 2014 are thus included below. Facility staff highlighted in bold text.

Papers authored by imaging core staff

  1. Lee J, Boyce S, Powers J, Baer C, Sassetti CM, Behar SM. CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis. PLoS Pathog. 2020;16(6):e1008621. Published 2020 Jun 16. PMCID: PMC7319360  DOI: 1371/journal.ppat.1008621
  2. Mondo E, Becker SC, Kautzman AG, Schifferer M, Baer CE, Chen J, Huang E J, Simons M, Schafer DP. A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature [published online ahead of print, 2020 Jul 13]. J Neurosci. 2020;JN-RM-3006-19. PMID: 32661024 DOI: 1523/JNEUROSCI.3006-19.2020
  3. Lovewell RR, Baer CE, Mishra BB, Smith CM, Sassetti CM. Granulocytes act as a niche for Mycobacterium tuberculosis growth [published online ahead of print, 2020 Jun 1]. Mucosal Immunol. 2020. PMID: 32483198 DOI: 1038/s41385-020-0300-z
  4. Brown CW, Amante JJ, Chhoy P, Elaimy AL, Liu H, Zhu LJ, Baer CE, Dixon SJ, Mercurio AM. Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export. Dev Cell. 2019;51(5):575-586.e4. PMID: 31735663 DOI: 1016/j.devcel.2019.10.007
  5. Elaimy AL, Wang M, Sheel A, Brown CW, Walker MR, Amante JJ, Xue W, Chan A, Baer CE, Goel HL, Mercurio AM. Real-time imaging of integrin β4 dynamics using a reporter cell line generated by Crispr/Cas9 genome editing. J Cell Sci. 2019;132(15):jcs231241. Published 2019 Jul 31. PMCID: PMC6703706 (available on 2020-08-01) DOI: 1242/jcs.231241
  6. Murphy KC, Nelson SJ, Nambi S, Papavinasasundaram K, Baer CE, Sassetti CM. ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes. mBio. 2018;9(6):e01467-18. Published 2018 Dec 11. PMCID: PMC6299477 DOI: 1128/mBio.01467-18
  7. Jungnickel MK, Sutton KA, Baker MA, Cohen MG, Sanderson MJ, Florman HM. The flagellar protein Enkurin is required for mouse sperm motility and for transport through the female reproductive tract. Biol Reprod. 2018;99(4):789-797. PMCID: PMC6203878   DOI: 1093/biolre/ioy105
  8. Chen J, Miller M, Unno H, Rosenthal P, Sanderson MJ, Broide DH. Orosomucoid-like 3 (ORMDL3) upregulates airway smooth muscle proliferation, contraction, and Ca2+ oscillations in asthma. J Allergy Clin Immunol. 2018;142(1):207-218.e6. PMCID: PMC5842097  DOI: 1016/j.jaci.2017.08.015
  9. Mishra BB, Lovewell RR, Olive AJ, Zhang G, Wang W, Eugenin E, Smith CM, Phuah JY, Long JE, Dubuke ML, Palace, SG, Goguen JD, Baker RE, Nambi S, Mishra R, Booty MG, Baer CE, Shaffer SA, Dartois V, McCormick, BA, Chen X, Sassetti CM. Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis. Nat Microbiol. 2017;2:17072. Published 2017 May 15. PMCID: PMC5461879  DOI: 1038/nmicrobiol.2017.72
  10. Chen J, Sanderson MJ. Store-operated calcium entry is required for sustained contraction and Ca2+ oscillations of airway smooth muscle. J Physiol. 2017;595(10):3203-3218. PMCID: PMC5430234   DOI: 1113/JP272694
  11. Yocum GT, Chen J, Choi CH, Townsend EA, Zhang Y, Xu D, Fu XW, Sanderson MJ, Emala CW. Role of transient receptor potential vanilloid 1 in the modulation of airway smooth muscle tone and calcium handling. Am J Physiol Lung Cell Mol Physiol. 2017;312(6):L812-L821. PMCID: PMC5495950  DOI: 1152/ajplung.00064.2017
  12. Boie S, Chen J, Sanderson MJ, Sneyd J. The relative contributions of store-operated and voltage-gated Ca2+ channels to the control of Ca2+ oscillations in airway smooth muscle. J Physiol. 2017;595(10):3129-3141. PMCID: PMC5430232 DOI: 1113/JP272996
  13. Sneyd J, Han JM, Wang L, Chen J, Yang X, Tanimura A, Sanderson MJ, Kirk V, Yule DI. On the dynamical structure of calcium oscillations. Proc Natl Acad Sci U S A. 2017;114(7):1456-1461. PMCID: PMC5321031 DOI: 1073/pnas.1614613114
  14. Hayashi JM, Luo CY, Mayfield JA, Hsu T, Fukuda T, Walfield AL, Giffen SR, Leszyk JD, Baer CE, Bennion OT, Madduri A, Shaffer SA, Aldridge BB, Sassetti CM, Sandler SJ, Kinoshita T, Moody DB, Morita YS. Spatially distinct and metabolically active membrane domain in mycobacteria. Proc Natl Acad Sci U S A. 2016;113(19):5400-5405. PMCID: PMC4868426   DOI: 1073/pnas.1525165113
  15. Bai Y, Krishnamoorthy N, Patel KR, Rosas I, Sanderson MJ, Ai X. Cryopreserved Human Precision-Cut Lung Slices as a Bioassay for Live Tissue Banking. A Viability Study of Bronchodilation with Bitter-Taste Receptor Agonists. Am J Respir Cell Mol Biol. 2016;54(5):656-663. PMCID: PMC4942196 DOI: 1165/rcmb.2015-0290MA
  16. Croisier H, Tan X, Chen J, Sneyd J, Sanderson MJ, Brook BS. Ryanodine receptor sensitization results in abnormal calcium signaling in airway smooth muscle cells. Am J Respir Cell Mol Biol. 2015;53(5):703-711. PMCID: PMC4742950 DOI: 1165/rcmb.2014-0386OC
  17. Awata J, Song K, Lin J, King SM, Sanderson MJ, Nicastro D, Witman GB. DRC3 connects the N-DRC to dynein g to regulate flagellar waveform. Mol Biol Cell. 2015;26(15):2788-2800. PMCID: PMC4571338   DOI: 1091/mbc.E15-01-0018
  18. Rietdorf K, Masoud S, McDonald F, Sanderson MJ, Bootman MD. Pulmonary vein sleeve cell excitation-contraction-coupling becomes dysynchronized by spontaneous calcium transients. Biochem Soc Trans. 2015;43(3):410-416. PMID: 26009184 DOI: 1042/BST20140299
  19. Kieser KJ, Boutte CC, Kester JC, Baer CE, Barczak AK, Meniche X, Chao MC, Rego EH, Sassetti CM, Fortune SM, Rubin EJ. Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria. PLoS Pathog. 2015;11(6):e1005010. Published 2015 Jun 26.  PMCID: PMC4483258   DOI: 1371/journal.ppat.1005010
  20. Awata J, Song K, Lin J, King SM, Sanderson MJ, Nicastro D, Witman GB. DRC3 connects the N-DRC to dynein g to regulate flagellar waveform. Mol Biol Cell. 2015 Aug 1;26(15):2788-800. Epub 2015 Jun 10. PMCID: PMC4571338  DOI: 1091/mbc.E15-01-0018
  21. Baer CE, Iavarone AT, Alber T, Sassetti CM. Biochemical and spatial coincidence in the provisional Ser/Thr protein kinase interaction network of Mycobacterium tuberculosis. J Biol Chem. 2014;289(30):20422-20433. PMCID: PMC4110253  DOI: 1074/jbc.M114.559054
  22. Bourke JE, Bai Y, Donovan C, Esposito JG, Tan X, Sanderson MJ. Novel small airway bronchodilator responses to rosiglitazone in mouse lung slices. Am J Respir Cell Mol Biol. 2014;50(4):748-756. PMCID: PMC4068922  DOI: 1165/rcmb.2013-0247OC
  23. Meniche X, Otten R, Siegrist MS, Baer CE, Murphy KC, Bertozzi CR, Sassetti CM. Subpolar addition of new cell wall is directed by DivIVA in mycobacteria. Proc Natl Acad Sci U S A. 2014;111(31):E3243-E3251. PMCID: PMC4128124 DOI: 1073/pnas.1402158111
  24. Rietdorf K, Bootman MD, Sanderson MJ. Spontaneous, pro-arrhythmic calcium signals disrupt electrical pacing in mouse pulmonary vein sleeve cells. PLoS One. 2014;9(2):e88649. Published 2014 Feb 20. PMCID: PMC3930634  DOI: 1371/journal.pone.0088649
  25. Tan, X and Sanderson, MJ. Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity. Br J Pharmacol. 2014 Feb;171(3):646-62. PMCID: PMC3969078 DOI: 1111/bph.12460
  26. Sanderson MJ, Smith I, Parker I, Bootman MD. Fluorescence microscopy. Cold Spring Harb Protoc. 2014;2014(10):pdb.top071795. Published 2014 Oct 1. PMCID: PMC4711767 DOI: 1101/pdb.top071795
  27. Cao P, Tan X, Donovan G, Sanderson MJ, Sneyd J. A deterministic model predicts the properties of stochastic calcium oscillations in airway smooth muscle cells. PLoS Comput Biol. 2014;10(8):e1003783. Published 2014 Aug 14. PMCID: PMC4133161 DOI: 1371/journal.pcbi.1003783