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Spotlight on Gene Therapy: finding a Cure

Outstanding Poster Prize at 2016 ASGCT for Mueller Lab's alpha-one antitrypsin work

Posted On: Monday, May 09, 2016 Posted By: Florie Borel Tags: Alpha-one antitrypsin, Gene Therapy, Presentations

We are thrilled that our lab represented by Florie Borel received the Outstanding Poster Award at ASGCT 2016 in Washington, DC for our poster: "Genome editing to generate the first mouse model of alpha-one antitrypsin deficiency, the leading cause of genetic COPD".

In this poster, we described how we generated and characterized the first AAT knockout mouse model using the CRISPR/Cas9 technology. Up to now, there was no mouse model for alpha-one antitrypsin deficiency lung disease, and these mice will be valuable to test new therapeutics including gene therapy and genome editing.

2016 ASGCT poster award