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Spotlight on Gene Therapy: finding a Cure

Mueller Lab to present at ASGCT 2015

Posted On: Thursday, April 02, 2015 Posted By: Florie Borel Tags: Adeno-associated virus, Alpha-one antitrypsin, Gene Therapy, Immunology, Presentations

Chris Mueller will present our work on a novel humanized liver mouse model in an oral presentation entitled "Selective Advantage of Hepatocytes Expressing Wild-Type Alpha-1 Antitrypsin (AAT) in a Novel Human Liver Xenograft Model: A Model for Correction of a Gain-Of-Function Mutation" at the American Society of Gene and Cell Therapy 2015 Annual Meeting, on May 13-16 in New Orleans, Louisiana.

Our lab will also present three posters:

  • Chris Mueller will present "Simultaneous Disruption of Five SerpinA1 Genes in Mice Using CRISPR/Cas9 to Generate the First Animal Model of Alpha-1 Antitrypsin Deficiency".
  • Gwladys Gernoux will present "Detection and Characterization of Immune Response Against AAVrh10 Vector After Intrathecal Vector Delivery in Non-Human Primates".
  • Florie Borel will present "Developing Strategies To Improve the Current Clinical Vector AAV1-CB-AAT for Alpha-One Antitrypsin Deficiency".