About the dean
Terence R. Flotte, MD, is provost, dean and executive deputy chancellor of UMass Chan Medical School, the only public medical school in Massachusetts. Since joining UMass Chan in 2007, Dr. Flotte has forged a path of unprecedented growth and achievement for the research, education and academic missions of the campus. An internationally known scientist, Flotte has conducted research on cutting edge molecular therapeutics that led to the first successful gene transfer with adeno-associated virus (AAV) in animals and the first ever human trial of an AAV. He also led the first human recombinant AAV trials in alpha-1 antitrypsin deficiency and Tay-Sachs disease, with the latter showing promising clinical benefits. He is the author of more than 280 scholarly papers and his research has been funded by the National Institutes of Health and the Alpha One Foundation. Since 2015, Flotte has also been editor-in-chief of gene therapy’s oldest journal family, Human Gene Therapy.
News articles
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Top story: Catherine’s story: Tay-Sachs disease
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Top story: Amid NIH funding cuts and uncertainty, Gov. Healey says future of science, research in Massachusetts is at stake
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Top story: UMass Chan celebrates naming of Paul J. DiMare Center
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Alpha Omega Alpha Honor Medical Society inducts 56 leaders, mentors, researchers
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Jessica Spinelli, Emma Watson named to distinguished HHMI scholars program
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UMass Chan licenses monoclonal antibody for seasonal prevention of Lyme disease to Tonix Pharmaceuticals
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Chancellor Collins’ final Convocation address encourages optimism, determination
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UMass Chan celebrates start of academic year with Convocation Week 2025
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