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Publication number: 20120232130
Abstract: The present invention is directed to methods for the treatment or prevention of starvation in a cell, e.g., a neuronal cell, and methods for the treatment and prevention of disorders associated therewith by the administration of an agent, e.g., a nucleic acid molecule, which enhances the intracellular generation and/or uptake of glucose, pyruvate, lactate, and/or NADPH.
Type: Application
Filed: April 15, 2010
Publication date: September 13, 2012
Inventors: Constance L. Cepko, Claudio Punzo
Publication number: 20110318424
Abstract: The present invention is directed to the use of modulators of the mammalian target of rapamycine (mTOR) pathway, glucose and/or glucose enhancers for treating retinal disorders and, in particular, for prolonging the viability of cone cells.
Type: Application
Filed: December 3, 2009
Publication date: December 29, 2011
Inventors: Constance Louise Cepko, Claudio Punzo