The MassBiologics Main Campus consists of a research and administration building and a manufacturing building.
The manufacturing building houses approximately 25,000 square feet of cGMP manufacturing space with dedicated areas for aseptic fill finish and bulk drug substance production. The FDA approved filling area features a vial washing and depyrogenation tunnel meshed with a Bosch high speed filler capable of filling and capping 300 vials per minute. The packaging area is equipped with a laser printing IMA labeler, cartoner and case packer. The labeling process is monitored using state of the art camera technology. The bulk drug substance preparation area includes dedicated rooms for seed preparation, bioreactor culture and purification. Bulk cell culture is accomplished using a 55L, 500L and 2500L ABEC reactor train. The manufacturing building also houses ambient and cold warehouse storage, clean utilities, QC testing laboratories and office space.
The research building houses laboratory space for product discovery and process development scientists and equipment. MassBiologics' administration, clinical and regulatory offices are also located here.
MassBiologics’ 30,000 square foot South Coast facility in Fall River is dedicated to the development and cGMP production of viral vector based therapeutics. The facility is designed, maintained and operated to manufacture these cutting-edge therapeutics under the highest quality standards. The facility can support production of a wide variety of viral vectors, including AAV, AdV & Lenti virus using adherent, suspension adapted and insect cell lines. Suspension adapted processes are executed in single-use bioreactors. The facility also maintains a dedicated aseptifc filling suite with a fully automated fill line, capable of filling lot sizes from a few hundred vials up to approximately 25,000 vials per campaign. The facility also houses a viral vector process development lab ready to support a variety of project needs.