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Bioinformatics & Computational Biology

REQUIREMENTS FOR SPECIALIZATION

Students in the Bioinformatics & Computational Biology program must take 3 elective courses, two of which must be in Bioinformatics. Additional elective courses can be chosen from among those offered by the program, or relevant courses offered by other GSBS programs. The plan of coursework is designed to be flexible in order to accommodate each student’s needs and areas of interest.

View year by year course sequence for Basic Biomedical Science doctoral students. 

For further guidance on program requirements or expectations, please contact the appropriate program director(s)

Courses

  • Professionalism and Research Conduct (PARC) | BBS 601

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    This is a required course for all third year Basic Sciences students and all MD/PhD students entering doctoral study but who are not on the CPHR track. The PARC course helps to center our students in areas that are foundational to success in research: responsible data management; management of intellectual property; the ethical use of research subjects; recognizing and resolving conflicts of interest, professionalism in peer review and publishing; engaging mentors; and career exploration and planning. The PARC course comprises faculty-led presentations and small group discussions with case studies and workshop material. An online learning module (CITI training program comprising many case studies) is also included and must be completed before the end of the fall semester. 

    Course Directors: Anthony Imbalzano, Cynthia Fuhrmann

    Semester Offered: Fall 

    Last Taught: Fall 2021

  • Preparation for Qualifying Exam | BBS 602

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    This course seeks to help prospective scientists in the biological and medical sciences communicate their work effectively, in writing, graphics, and oral presentations. The course teaches how to prepare a research paper using words, statistics, and figures; how to present science to a lay audience; how to write a grant proposal; and how to present orally to scientific peers.

    Course Directors: Jill Zitzewitz, Daryl Bosco, and Nese Kurt Yilmaz

    Semester Offered: Fall 

    Last Taught: Fall 2021

  • Foundations in Biomedical Science | BBS 614

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    This problem-based course provides learning opportunities through exploration of multidisciplinary areas of contemporary biomedical research, and creates a forum for practice in the skills required for research.

    Course Directors: Jill Zitzewitz, Sean Ryder, Neal Silverman

    Semester Offered: Fall 

    Last Taught: Fall 2021

  • Molecular Evolution | BBS 705

    Programs: Bioinformatics & Computational Biology

    The course will focus on the quantitative study of molecular evolution using sequence and structural data, showing how both classical and novel methods in population genetics, bioinformatics and computational biology can be used to assess the variability in the genomic sequences and make inferences about the underlying processes of natural selection and evolution. The course is primarily aimed at the students interested in quantitative aspects of biology, and may be useful to practicing biologists desiring a deeper understanding of the computational and statistical techniques. 

    Course Director: Bioinformatics & Computational Biology Faculty

    Semester Offered: Spring

    Last Taught: Spring 2016

  • An Empirical Introduction to Statistical Modeling | BBS 706

    Programs: Bioinformatics & Computational Biology

    Lecture and textbook based course on statistical modeling and machine learning, with exercises on analyzing real data.

    Course DirectorManuel Garber

    Semester Offered: Fall, odd years

    Last Taught: Fall 2021

  • Advanced Topics in Bioinformatics | BBS 741

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology

    The Advanced Topics in Bioinformatics course covers several important areas of modern bioinformatics and computational biology. The course is aimed not only at students specializing in bioinformatics, but also general biology students who would like to utilize bioinformatics tools in their daily research. The course will begin with an overview of modern sources of bioinformatics data, especially high-throughput sequencing data (RNA-seq, ChIP-seq, DNase-seq, ATAC-seq, Whole genome bisulfite sequencing, etc.), followed by a thorough presentation of an extensive set of statistical learning and machine learning algorithms and their application to analyzing biological data. The course will include 10 lectures each with a homework set, followed by individual or group projects, presented in lieu of the final exam. 

    Course Director: Zhiping Weng

    Semester Offered: Fall, Even Years

    Last Taught: Fall 2020

  • Systems and Computational Biology | BBS 764

    Programs: Bioinformatics & Computational Biology, Interdisciplinary

    This is a lecture and paper-discussion based course covering a broad range of topics in Systems Biology and Computational biology. 

    Course Director: Marian Walhout

    Semester Offered: Spring

    Last Taught: Spring 2020

  • Research Rotation | BBS 850

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Research rotations are defined periods of research experience under the direction of a faculty member. They are intended to familiarize the student with concepts and techniques in several areas of research and to assist the student in evaluating research laboratories and projects that might be developed into a dissertation project. The student will participate in an ongoing research project; gain familiarity with concepts underlying the research; acquire a working knowledge of techniques used in the research; and write a report and present an oral summary of the results of the research. 

    Course Director: Varies

    Semester Offered: Fall, Spring, Summer

    Last Taught: Taught every Fall and Spring semester

  • Research Rotation | BBS 851

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Research rotations are defined periods of research experience under the direction of a faculty member. They are intended to familiarize the student with concepts and techniques in several areas of research and to assist the student in evaluating research laboratories and projects that might be developed into a dissertation project. The student will participate in an ongoing research project; gain familiarity with concepts underlying the research; acquire a working knowledge of techniques used in the research; and write a report and present an oral summary of the results of the research. 

    Course DirectorVaries

    Semester Offered: Summer

    Last Taught: Taught every Summer

  • BBS Qualifying Exam | BBS 860

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Students are required to register for this course in the fall semester of the academic year in which they are to pass their Qualifying Examination.

    Course Director: Mary Ellen Lane

    Semester Offered: Fall

    Last Taught: Taught every year 

  • BBS TRAC Meeting | BBS 865

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    All graduate students are required to have at least one Thesis Research Advisory Committee (TRAC) meeting each academic year. After passing their Qualifying Examination and selection of their TRAC, students are required to register for this course each fall semester until their Dissertation Advisory Committee is formed.

    MD/PhD Goals: 1) To periodically review progress along thesis research project advised by content experts 2) To provide guidance for establishing a thesis research project consistent with the MD/PhD Program goals

    MD/PhD Curricular Expectations: Two Thesis Research Advisory Committee (TRAC) meeting each academic year as define by the Professionalism Benchmark Checklist

    Course Director: Mary Ellen Lane

    Semester Offered: Fall

    Last Taught: Taught every year

  • Prequalifying Research | BBS 870

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    This course is for students who have selected a program and thesis advisor but who have not yet passed the Qualifying Examination. 

    Course Director: Student's thesis advisor

    Semester Offered: Fall, Spring, Summer

    Last Taught: Taught every semester

  • Thesis Research | BBS 900

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Students register for Thesis Research fall term of year three of the program (MD/PhD Students: Fall term of year four in the program), after passing the Qualifying Exam.

    Course Director: Student's thesis advisor

    Semester Offered: Fall, Spring, Summer

    Last Taught: Taught every semester

  • Graduate Research | BBS 990

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Students register for Graduate Research fall term of year four (MD/PhD Students: Fall term of year five+) in the PhD Program and will continue to register each semester until they complete all remaining requirements.

    Course Director: Student's thesis advisor

    Semester Offered: Fall, Spring, Summer

    Last Taught: Taught every semester

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