Brehm Lab News

Mina Seedhom, PhD, leads our studies reconstructing human type 1 diabetes with stem cell-derived islets in our novel humanized mice to observe interactions with immune cells in vivo to evaluate potential therapies.

The review article outlines safety and manufacturing standards for advancing stem cell-derived islet therapies for type 1 diabetes to clinical trials.

Succeeding his longtime mentor Dale Greiner, PhD, Dr. Brehm joins Dr. David Harlan in leading UMass Chan's research aimed to prevent and ultimately cure type 1 diabetes.

Carey tests islet transplants and protective devices in preclinical humanized mouse studies as we identify ways to shield islets and beta cells from immune attack.