Faculty by Last Name

Focus: C.elegans behavioral genetics

Focus: Understanding the molecular mechanisms of frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS) and Alzheimer disease (AD).

Focus:  Assessing how vertebrate hosts and their immune system interact with intestinal nematodes, with the goal of controlling autoimmune diseases including MS; cognitive impact of parasitic nematodes.

Higgins Family Professor of Neuroscience

Focus: Neurodegenerative diseases, especially Parkinson's and Huntington's diseases.

Lab Web-page

Focus: Neuronal Cell Fate Specification.      

Focus:  Cell death and autophagy.

Focus: Clinical Neuropsychiatry and neuropsychiatry training. 

Focus: Macrophages and the enteric nervous system in intestinal health and disease

Focus: Pathogenic mechanisms underlying Amyotrophic Lateral Sclerosis; protein misfolding in ALS

Lab Webpage

Focus: Activity-dependent gene expression in the primate brain

Leo P. and Theresa M. LaChance Chair in Medical Research

Focus: Identification of gene defects in neuromuscular diseases; Amyotrophic Lateral Sclerosis.

Focus: Mechanisms of axon regeneration and degeneration in the aging nervous system

Focus: Using induced pluripotent stem cells from patient samples to model Herpes viral infection as a cause of Alzheimer’s disease and Hearing-loss due to Cisplatin treatment.

Link to Lab Page

Focus: Epilepsy

Investigator, Howard Hughes Medical Institute

H. Arthur Smith Chair in Cancer Research

Focus: Mechanisms by which growth factors regulate cellular proliferation and signaling.

Director, Department of Animal Medicine

Focus: Investigate neuromuscular diseases with an emphasis on congenital and other muscular dystrophies; cell death mechanisms and inflammatory pathway regulation.

PI, Wellstone Muscular Dystrophy Program at UMass Chan Medical School

Focus: Muscular Dystrophies

Lab website

Focus: Circadian Rhythms and photoreception in Drosophila.

Focus: Schizophrenia

Focus: Identification of drug targets and small molecules to treat Fragile X Syndrome and Friedreich's Ataxia

Focus: Activity-dependent synaptic plasticity; Neuronal circuit development and function in C. elegans.

Lab Webpage

Director, Eunice Kennedy Shriver Center

Robert M. and Shirley S. Siff Chair in Autism

Focus: Autism, early onset schizophrenia and bipolar disorder, neuroimaging, psychopharmacology.

The Child and Adolescent NeuroDevelopment Initiative (CANDI)

Focus: The roles of Inhibitory neurons in neuropsychiatric diseases.

Focus: Undergraduate and graduate neuroanatomy education.

The Governor Paul Cellucci Chair in Neuroscience Research

Focus: Understanding Frontotemporal Dementia (FTD) and ALS.

Lab Webpage

Penelope Booth Rockwell Chair in Biomedical Research

Director, Horae Gene Therapy Center

Focus: Adeno-associated virus vectors for gene therapy of genetic diseases including Canavan Disease

Focus: Immune system dysfunction including multiple sclerosis, with an emphasis on B lymphocyte contribution to pathology and biomarkers of disease progression.

Focus: Neurogenetics; lysosomal storage disorders.

Director, New England Center for Stroke Research

Focus: Minimally invasive neuroendovascular surgery

Focus: Adeno-Associated Virus (AAV) gene therapy in animal models of Sandhoff and Tay-Sachs diseases

Focus: Motor neuron degeneration in amyotrophic lateral sclerosis.

Focus: Multiple Sclerosis, Neuroimaging, Psychoneuroimmunology

Focus: Stroke and brain injury.

Focus: Multiple sclerosis and other autoimmune neurological diseases; and neurological complications of HIV infections.

Marcellette G. Williams Scholar

Focus: Neural-immune communication; Comparative immunology.

Lab website

Gerald L. Haidak, MD, and Zelda S. Haidak Professorship in Cell Biology (est. 1999)

Focus: Post-transcriptional control of gene expression in model systems and genetic disorders

Focus: Normal-pressure hydrocephalus; gliomas

Focus: Gene Therapy, T-REGS and immune response to AAVs

Focus: Neuro-imaging and Neuroinformatics; functional MRI, morphometric analysis.

Remondi Family Chair in Biomedical Research

Focus: Therapeutic gene silencing in vivo.

Focus: Identifying alterations in metabolic pathways supporting cancer cells (gliomas) and exploiting these alterations for therapeutic purposes.

Lab website

Focus: Human brain development and maternal-infant bonding

Focus: Structure, Function and Modulation of Ion Channels.

Lab Webpage

Focus: Genetics of Familial and Sporadic ALS.

Focus: Chromosome silencing, Down Syndrome, and Alzheimer Disease

Lab Web-page

Focus: Computer vision and image processing.

Focus: To understand the genetic mechanisms of complex neurological diseases (ASD and Alzheimer’s) through computational and statistical methods and experimental technology.

Lab website

Focus: Translational regulation in models of Fragile X Syndrome.

Focus: The role of mitochondria and the endoplasmic reticulum in neurodegeneration and aging.

Lab website

Focus: Bipolar and mood disorders, reproductive phases in women.

Focus: Drugs of abuse and memory; electrophysiology.

Focus: Mucosal inflammation, host:pathogen interactions, and cancer biology.

Focus: Cocaine and antidepressant-sensitive monoamine transporters.

Focus: Adult brain tumors, stereotactic radiosurgery, translational research.

Focus: Regulation of vesicle targeting and fusion.

Director, Epilepy Service

Focus: Epilepsy

Focus: Using small to macromolecular drug delivery to phagocytes to modulate inflammation and pathologies associated with infectious, autoimmune and neurodegenerative diseases.

Vitold Arnett Professorship in Cell Biology

Focus: RNA traffic in eukaryotic cells, RNA processing, RNA-protein interactions, microRNAs.

Focus: Neurodegeneration in the retina; retinitis pigmentosa.

Lab Web-page

Director for Clinical Research, NeuroNexus Institute
Director, Division of Neurointerventional Surgery
Director, Neurointerventional Fellowship Program

Research Focus: Stroke treatment using mechanical thrombectomy, an endovascular procedure that is performed in neurointerventional radiology.

Arthur F. Koskinas Chair in Neuroscience

Focus: Translational control in meiosis, mitosis, and neuronal synaptic plasticity. Fragile X syndrome.

Focus: Calcium Channels and Neuronal Plasticity.

Focus: Molecular genetic mechanisms of neuropsychiatric diseases and dementia.

Irving S. and Betty Brudnick Chair in Psychiatry

Focus: Clinical Research in Affective Disorders and Sexual Dysfunction; Psychopharmacology.

Focus: Post-transcriptional regulation of maternal mRNA in development.

Lab Webpage

Focus: Structural and Functional Neuroimaging, Image Processing

Focus: Neuron-glia interactions regulating synaptic circuit development and plasticity.

Focus: Preclinical gene therapy of neurological diseases and brain cancer.

Focus: Parkinson’s disease, Movement disorders, biomarker development

Focus: Forensic neuropathology and CNS neoplasia.

Director, Brudnick Neuropsychiatric Research Institute

Focus: Neuronal nicotinic acetylcholine receptors in addiction and neurological disease.

Director, Small Molecule Screening Facility

Focus: Transposon regulation of neuromuscular junction plasticity

Focus: Molecular and cellular functions of the OXR family of oxidation resistance genes in order to determine how they protect cells from oxidative stress induced DNA damage and cell death.

Focus: Anesthesiology

Focus: AAV Gene Therapy for Genetic Diseases

Focus: Therapeutic gene silencing with chemically modified antisense oligonucleotides.

Executive Director, NeuroNexus Institute
Director, Graduate Program in Neuroscience

Focus: Molecular regulation and physiological impact of circadian rhythms.

Focus: Molecular and neural circuit mechanisms underlying behavior; light-evoked escape behavior.

Focus: Mechanism and therapy of neurodegenerative diseases including FTD and ALS.

Focus: Neural activity and behavioral changes during development

Lab website

Focus: Cancer; Chromosomal silencing and Trisomy 21

Focus: Interplay of sensory systems and internal state; taste

Lab website

Focus: Smooth muscle in health and disease.

Focus: Protein Misfolding and Disease.