Faculty by Last Name

Focus: C.elegans behavioral genetics

Focus: Understanding the molecular mechanisms of frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS) and Alzheimer disease (AD).

Focus:  Assessing how vertebrate hosts and their immune system interact with intestinal nematodes, to control autoimmune diseases including MS; and the cognitive impact of parasitic nematodes.

Higgins Family Professor of Neuroscience
Focus: Neurodegenerative diseases, especially Parkinson's and Huntington's diseases.
Lab Web-page

Focus: Neuronal Cell Fate Specification.      

Focus: Cell death and autophagy.

SCOPE Imaging Core Director

Focus: Light microscopy and spatial 'omics

Focus: Developing gene therapies for untreatable genetic diseases affecting the CNS  

Focus: Clinical Neuropsychiatry and neuropsychiatry training

Focus: Macrophages and the enteric nervous system in intestinal health and disease

Paul J. DiMare Chair in Neurodegenerative Disease   
Focus: Pathogenic mechanisms underlying Amyotrophic Lateral Sclerosis; protein misfolding in ALS
Lab Webpage

Focus: Activity-dependent gene expression in the primate brain

Focus: Genetic modeling of disease

Donna M. and Robert J. Manning Chair in Neuroscience
Focus: Identification of gene defects in neuromuscular diseases; Amyotrophic Lateral Sclerosis

Focus: Mechanisms of axon regeneration and degeneration in the aging nervous system

Focus: Cellular and molecular mechanisms underlying motor learning

Focus: Using induced pluripotent stem cells from patient samples to model Herpes viral infection as a cause of Alzheimer’s disease and hearing loss due to Cisplatin treatment.
Lab WebPage

Focus: Epilepsy

Barrett Family Term Chair in Neurodevelopmental Disorders
Focus: Neurodevelopmental disorders

Endowed Chair in Diabetes
Focus: Adipose tissue biology and metabolic diseases.

The Isadore and Fannie Foxman Chair of Medical Research
Focus: Investigating cellular and molecular interations among metabolic tissues, macrophages, neuronal signals and the vasculature that define both normal and metabolic disease states.

Focus: Developing gene therapies for rare neurological and neuromuscular diseases.

Investigator, Howard Hughes Medical Institute

H. Arthur Smith Chair in Cancer Research
Focus: Mechanisms by which growth factors regulate cellular proliferation and signaling.

Director, Department of Animal Medicine

Focus: Investigate neuromuscular diseases with an emphasis on congenital and other muscular dystrophies; cell death mechanisms and inflammatory pathway regulation.

Associate Director NeuroNexus Institute

Focus: Sensory perception in people with or at risk for mood and anxiety disorders.

PI, Wellstone Muscular Dystrophy Program at UMass Chan Medical School

Focus: Muscular Dystrophies
Lab website

Focus: Circadian Rhythms and photoreception in Drosophila.

Focus: Schizophrenia

Focus: Identification of drug targets and small molecules to treat Fragile X Syndrome and Friedreich's Ataxia

Focus: Activity-dependent synaptic plasticity; Neuronal circuit development and function in C. elegans.
Lab Webpage

Director, Eunice Kennedy Shriver Center

Robert M. and Shirley S. Siff Chair in Autism
Focus: Autism, early onset schizophrenia and bipolar disorder, neuroimaging, psychopharmacology.
The Child and Adolescent NeuroDevelopment Initiative (CANDI)

Focus: The roles of Inhibitory neurons in neuropsychiatric diseases.

Focus: Undergraduate and graduate neuroanatomy education.

The Governor Paul Cellucci Chair in Neuroscience Research
Focus: Understanding Frontotemporal Dementia (FTD) and ALS.
Lab Webpage

Director, Horae Gene Therapy Center

Penelope Booth Rockwell Chair in Biomedical Research
Focus: Adeno-associated virus vectors for gene therapy of genetic diseases including Canavan Disease

Focus: Immune system dysfunction including multiple sclerosis, with an emphasis on B lymphocyte contribution to pathology and biomarkers of disease progression.

Focus: Gene Therapy and Neurometabolism for Rare Neurological Diseases.

Focus: Neurogenetics; lysosomal storage disorders.

Director, New England Center for Stroke Research

Focus: Minimally invasive neuroendovascular surgery

Focus: Adeno-Associated Virus (AAV) gene therapy in animal models of Sandhoff and Tay-Sachs diseases

Focus: Non-GPCR Chemosensors for Mammalian Olfaction

Focus: Gene therapy in large animal models

Focus: Epigenetic Regulation and Nuclear Structure

Focus: Motor neuron degeneration in amyotrophic lateral sclerosis.

Focus: Multiple Sclerosis, Neuroimaging, Psychoneuroimmunology

Focus: Stroke and brain injury.

Focus: Immunometabolism in neurodegeneration

Focus: Multiple sclerosis and other autoimmune neurological diseases; and neurological complications of HIV infections.

Marcellette G. Williams Scholar

Focus: Neural-immune communication; Comparative immunology.
Lab website

Gerald L. Haidak, MD, and Zelda S. Haidak Professorship in Cell Biology (est. 1999)
Focus: Post-transcriptional control of gene expression in model systems and genetic disorders

Senior Consulting Vice Provost for Mentorship, Leadership, and Transformation

Maroun Semaan Chair in Neurosurgery
Focus: Normal-pressure hydrocephalus; gliomas

Dr. Eileen L. Berman and Stanley I. Berman Foundation Chair in Biomedical Research
Focus: Comparative genomics and evolutionary biology in humans and dogs.

Focus: Gene Therapy, T-REGS and immune response to AAVs

Focus: Neuro-imaging and Neuroinformatics; functional MRI, morphometric analysis.

Remondi Family Chair in Biomedical Research
Focus: Therapeutic gene silencing in vivo.

Focus: Identifying alterations in metabolic pathways supporting cancer cells (gliomas) and exploiting these alterations for therapeutic purposes.
Lab website

Focus: Human brain development and maternal-infant bonding

Focus: Bioinformatic approaches in neurological diseases

Focus: Structure, Function and Modulation of Ion Channels.
Lab Webpage

Focus: Genetics of Familial and Sporadic ALS.

Leo P. and Thomas M. LaChance Chair in Medical Research
Focus: Chromosome silencing, Down Syndrome, and Alzheimer's Disease
Lab Web-page

Focus: Autoimmune Uveitis

Focus: To understand the genetic mechanisms of complex neurological diseases (ASD and Alzheimer’s) through computational and statistical methods and experimental technology.
Lab website

Focus: Developing translational gene therapy for mitochondrial disease with neurological manifestations, such as Leigh syndrome.

Focus: Addiction, neuropsychiatric diseases and circadian rhythms  
Lab Website: https://wickedneuro.com/

Focus: Translational regulation in models of Fragile X Syndrome.

Focus: The role of mitochondria and the endoplasmic reticulum in neurodegeneration and aging.
Lab website

Focus: Drugs of abuse and memory; electrophysiology.

Worcester Foundation for Biomedical Research Chair II
Focus: Mucosal inflammation, host:pathogen interactions, and cancer biology.

Focus: Cocaine and antidepressant-sensitive monoamine transporters.

Focus: Illuminating biological processes with chemistry.

Focus: Adult brain tumors, stereotactic radiosurgery, translational research.

Assistant Vice Provost for Health Equity

Focus: Regulation of vesicle targeting and fusion.

Focus: Primary cilia, hedgehog and Wnt signaling and extracellular matrix metalloproteinases

Director, Epilepsy Service

Focus: Epilepsy

Focus: Using small to macromolecular drug delivery to phagocytes to modulate inflammation and pathologies associated with infectious, autoimmune and neurodegenerative diseases.

Vitold Arnett Professorship in Cell Biology
Focus: RNA traffic in eukaryotic cells, RNA processing, RNA-protein interactions, microRNAs.

Focus: Chronic opioid use for the treatment of pain and prevention of side-effects and opioid addiction

Focus: Neurodegeneration in the retina; retinitis pigmentosa.
Lab Web-page

Director for Clinical Research, NeuroNexus Institute
Director, Division of Neurointerventional Surgery
Director, Neurointerventional Fellowship Program

Focus: Stroke treatment using mechanical thrombectomy, an endovascular procedure that is performed in neurointerventional radiology.

Focus: Scavenger receptors in inflammation and autoimmunology

Focus: Immunophenotype in Multiple Sclerosis, Neuropsychiatric Lupus and other conditions, neuroimmune interactions in the skin

Arthur F. Koskinas Chair in Neuroscience
Focus: Translational control in meiosis, mitosis, and neuronal synaptic plasticity, Fragile X syndrome.

Focus: Calcium Channels and Neuronal Plasticity.

Focus: Molecular genetic mechanisms of neuropsychiatric diseases and dementia.

UMass Memorial Chair in Radiology
Focus: Radiology

Irving S. and Betty Brudnick Chair in Psychiatry
Focus: Clinical Research in Affective Disorders and Sexual Dysfunction; Psychopharmacology.

Focus: Uncovering aberrant protein interactions in neurodegenerative diseases for biomarkers and therapeutic development.

Focus: Post-transcriptional regulation of maternal mRNA in development.
Lab Webpage

Focus: Structural and Functional Neuroimaging, Image Processing

UMass Chan Medical School Chair in Biomedical Research
Focus: Neuron-glia interactions regulating synaptic circuit development and plasticity.

Focus: Neuro-Immune Interactions; Neuropathogenesis of viral infection

Focus: Preclinical gene therapy of neurological diseases and brain cancer.

Focus: Parkinson’s disease, Movement disorders, biomarker development

Focus: Forensic neuropathology and CNS neoplasia.

Director, Brudnick Neuropsychiatric Research Institute
Focus: Neuronal nicotinic acetylcholine receptors in addiction and neurological disease.

Director, Small Molecule Screening Facility

Focus: Transposon regulation of neuromuscular junction plasticity

Focus: Uncovering mechanisms of neurodevelopmental disorders using zebrafish