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Our latest bioRxiv preprints

Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae
Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan, Chan Wu, Richard Baker, Allan Jacobson
bioRxiv 2020.12.15.422930; doi 

The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines
Jeremy Luban, Rachel Sattler, Elke Mühlberger, Jason D. Graci, Liangxian Cao, Marla Weetall, Christopher Trotta, Joseph M. Colacino, Sina Bavari, Caterina Strambio-De-Castillia, Ellen L. Suder, Yetao Wang, Veronica Soloveva, Katherine Cintron-Lue, Nikolai A. Naryshkin, Mark Pykett, Ellen M. Welch, Kylie O’Keefe, Ronald Kong, Elizabeth Goodwin, Allan Jacobson, Slobodan Paessler, Stuart Peltz
bioRxiv 2020.08.05.238394; doi


Our latest papers

Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae 
Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan, Chan Wu, Richard Baker, and Allan Jacobson
PLoS Genetics 17: e1009538, 2021; doi 

Dual mechanism of action of PTC299 and other DHODH inhibitors in suppressing SARS-CoV-2 replication and cellular cytokine storms 
Elizabeth Goodwin, Allan Jacobson, Marla Weetall, Jason D. Graci, Ellen M. Welch, Kylie O’Keefe, Stuart W. Peltz
J. Cytokine Biol. 6: 10037, 2021; doi 

Poly(A)-Binding Protein Regulates the Efficiency of Translation Termination
Chan Wu, Bijoyita Roy, Feng He, Kevin Yan, and Allan Jacobson
Cell Reports 33:108399, 2020; doi 

The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines
Jeremy Luban, Rachel A. Sattler, Elke Mühlberger et al.
Virus Research 292: 198246, 2021; doi