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Dale L. Greiner, PhD

Principal Investigator

The Herman G. Berkman Chair in Diabetes Care Innovation, Professor of Molecular Medicine and Co-Director of the Diabetes Center of Excellence at UMass Chan Medical School, Investigator at the JDRF Center of Excellence in New England 

Dr. Greiner is internationally recognized for developing the first successful “humanized” mouse model, in collaboration with The Jackson Laboratory. Researchers have relied upon these novel animals since the 1990s to model human diseases and study, among other things, the immune response to the transplantation of pancreatic islet cells for diabetes. This work has generated high interest in the biomedical research community for use as a preclinical model for the investigation of human diabetes, cancer, infectious disease, regenerative medicine and autoimmunity. The unique animal model allows Dr. Greiner and his team to investigate autoimmune type 1 diabetes and the cells that regulate immune responses in humans.

He currently serves as Vice Chair of the Institutional Animal Care and Use Committee, member of the Diabetes Research Center Executive Committee and the Flow Cytometry Advisory Committee. Over the past four decades he has co-authored more than 300 publications in the research specialization areas of Immunology, Transplantation, Autoimmunity and Diabetes. 

Dr. Greiner has served as a regular member of the National Institutes of Health Immunology Sciences Study Section and the Hypersensitivity, Autoimmune, and Immune-mediated Diseases Study Section. He has also served as Chair of the Veterans Administration Immunology Review Subcommittee B and Chair of many ad hoc NIH and JDRF study sections. In addition, he has served as Chair of the Medical Science Review Committee for the Juvenile Diabetes Research Foundation, Chairman of the American Diabetes Association Scientific Sessions Committee, as well as Program Chair and Council Chair of the American Diabetes Association Council on Immunology, Immunogenetics and Transplantation.

The recipient of numerous awards for his research, Dr. Greiner has received the A.J. Julian Scholarship for Academic Excellence, the Basil O'Connor Scholar Research Award from the March of Dimes, and the Kayla and Gerald Grodsky and the David Rumbough Awards from the Juvenile Diabetes Research Foundation, Int.  


B.S.,  University of Iowa, Iowa City, Iowa
M.T.,  University of Iowa at Veterans Administration Hospital, Iowa City, Iowa 
National Medical Technology Certification (ASCP)
Ph.D.,  Microbiology, University of Iowa, Iowa City, Iowa