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  • Summer Undergraduate Research Program provides hands-on experience, community collaboration

    Summer Undergraduate Research Program provides hands-on experience, community collaboration

    Thirty college students participated in the 2024 Summer Undergraduate Research Program at UMass Chan Medical School, refining their career goals through networking with peers and mentors, collaborative research and developing critical thinking skills.  

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  • Richard Gregory named chair of molecular, cell & cancer biology

    Richard Gregory named chair of molecular, cell & cancer biology

    Richard I. Gregory, PhD, an accomplished investigator of molecular mechanisms of RNA regulation in embryonic stem cells and cancer, will join UMass Chan Medical School as the next chair of the Department of Molecular, Cell & Cancer Biology, beginning in December.

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  • UMass Chan scientist seeks to overcome resistance to radiation therapy for breast cancer patients

    UMass Chan scientist seeks to overcome resistance to radiation therapy for breast cancer patients

    Research aimed at identifying the mechanisms that promote resistance to radiation therapy in patients with triple negative breast cancer is underway at UMass Chan Medical School by Arthur M. Mercurio, PhD, thanks to a new $2.6 million cancer research award from the National Institutes of Health.

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MCCB Upcoming Events

  • jueves, septiembre 12, 2024

    IN-HOUSE SEMINAR

    Time: 12:00 PM - 1:00 PM

    Michelle Kelliher, PhD


  • martes, septiembre 17, 2024

    SPECIAL SEMINAR

    Time: 11:00 AM - 12:00 PM

    Christopher Lengner, Ph.D. - Chair, Department of Biomedical Sciences
    University of Pennsylvania School of Veterinary Medicine

    “Colon Cancer: Stem cell origins and mechanisms of metastasis”


  • martes, septiembre 24, 2024

    SPECIAL SEMINAR

    Hosted By: Lucio Castilla, PhD
    Time: 11:00 AM - 12:00 PM

    Julio Aguirre-Ghiso, Ph.D. - Rose C. Falkenstein Chair in Cancer Research
    Endowed Professor of Cell Biology
    Director, Cancer Dormancy and Tumor Microenvironment Institute
    Albert Einstein College of Medicine

    “Alveolar macrophages, somatic mosaicism and the control of disseminated cancer cell dormancy”


More events...

MCCB Publications

Chibaya L et al. (2024) Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer.
Article | Ruscetti Lab

Liu H et al. (2024) CleanUpRNAseq:  An R/Bioconductor Package for Detecting and Correcting DNA Contamination in RNA-Seq Data.
Article |Bioinformatics Core

Flynn MJ et al. (2024) Calcineurin promotes adaptation to chronic stress through two distinct mechanisms.
Article | Benanti Lab

Kingsley SF et al. (2024) Glucose-fed microbiota alters C. elegans intestinal epithelium and increases susceptibility to multiple bacterial pathogens.
Article | Tissenbaum Lab

Ye T et al. (2024) Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma.
Article | Green Lab

O'Connor KW et al. (2024) The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance.
Article | Kelliher Lab

Mishra AK et al. (2024) Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer.
Article | Green Lab

Cong K et al. (2024) FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells.
Article | Cantor Lab

Lee N et al. (2024) Selenium reduction of ubiquinone via SQOR suppresses ferroptosis.
Article | Kim Lab

Kim S et al. (2024) Regulation of proteostasis and innate immunity via mitochondria-nuclear communication.
Article | Haynes Lab 

Roderick-Richardson JE et al. (2024) ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice.
Article | Kelliher Lab

Wang F et al. (2023) Roles of the Rlim-Rex1 axis during X chromosome inactivation in mice.
Article | Bach Lab

Mukhopadhyay D et al. (2023) The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing.
Article | Mercurio Lab

Doshi MB et al. (2023) Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells.
Article | Kim Lab

Ahmad MH et al. (2023) Runx1-R188Q germline mutation induces inflammation and predisposition to hematologic malignancies in mice.
Article | Castilla Lab

Shin M et al. (2023) Generation and application of endogenously floxed alleles for cell-specific knockout in zebrafish.
Article | Lawson Lab

Wang R et al. (2023) PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development.
Article | Baehrecke Lab

Liang SQ et al. (2023) Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag.
Article | Wolfe Lab

Xu Z et al. (2023) Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer.
A
rticle | Mercurio Lab

Conti MM et al. (2023) Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1. 
Article | Benanti Lab

Chibaya L et al. (2023) EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance.
Article | Ruscetti Lab

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