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Total: displaying 10 out of 19 results

The crystal and cryo-EM structures of PLCγ2 reveal dynamic interdomain recognitions in autoinhibition

Friday, November 29, 2024

Author(s): Young-Cheul Shin,Ashlee Marie Plummer-Medeiros,Alison Mungenast,Hyeong-Wook Choi,Karen TenDyke,Xiaojie Zhu,Jennifer Shepard,Kristen Sanders,Ningning Zhuang,Liang Hu,Dongming Qian,Kangkang Song,Chen Xu,John Wang,Suresh B Poda,Maofu Liao,Yu Chen

Source: Science advances
Structural basis of respiratory complex adaptation to cold temperatures

Saturday, October 12, 2024

Author(s): Young-Cheul Shin,Pedro Latorre-Muro,Amina Djurabekova,Oleksii Zdorevskyi,Christopher F Bennett,Nils Burger,Kangkang Song,Chen Xu,Joao A Paulo,Steven P Gygi,Vivek Sharma,Maofu Liao,Pere Puigserver

Source: Cell
Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition

Wednesday, September 04, 2024

Author(s): Shuhui Wang,Kun Wang,Kangkang Song,Zon Weng Lai,Pengfei Li,Dongying Li,Yajie Sun,Ye Mei,Chen Xu,Maofu Liao

Source: Nature communications
Structures of the essential efflux pump EfpA from Mycobacterium tuberculosis reveal the mechanisms of substrate transport and small-molecule inhibition

Tuesday, January 23, 2024

Author(s): Shuhui Wang,Kun Wang,Kangkang Song,Pengfei Li,Dongying Li,Yajie Sun,Ye Mei,Chen Xu,Maofu Liao

Source: Research square
Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing

Saturday, July 15, 2023

Author(s): Steven D Tettoni,Shawn B Egri,Dylan D Doxsey,Kristen Veinotte,Christna Ouch,Jeng-Yih Chang,Kangkang Song,Chen Xu,Kuang Shen

Source: Structure (London, England : 1993)
Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane

Wednesday, June 07, 2023

Author(s): Wei Shi,Yongfei Cai,Haisun Zhu,Hanqin Peng,Jewel Voyer,Sophia Rits-Volloch,Hong Cao,Megan L Mayer,Kangkang Song,Chen Xu,Jianming Lu,Jun Zhang,Bing Chen

Source: Nature
Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis

Monday, May 29, 2023

Author(s): Xuewu Sui,Kun Wang,Kangkang Song,Chen Xu,Jiunn Song,Chia-Wei Lee,Maofu Liao,Robert V Farese,Tobias C Walther

Source: Nature communications
Structural basis for GSDMB pore formation and its targeting by IpaH7.8

Wednesday, March 29, 2023

Author(s): Chengliang Wang,Sonia Shivcharan,Tian Tian,Skylar Wright,Danyang Ma,JengYih Chang,Kunpeng Li,Kangkang Song,Chen Xu,Vijay A Rathinam,Jianbin Ruan

Source: Nature
Author Correction: Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition

Wednesday, September 28, 2022

Author(s): Russell A Judge,Janani Sridar,Kathryn Tunyasuvunakool,Rinku Jain,John C K Wang,Christna Ouch,Jun Xu,Amirhossein Mafi,Aaron H Nile,Clint Remarcik,Corey L Smith,Crystal Ghosh,Chen Xu,Vincent Stoll,John Jumper,Amoolya H Singh,Dan Eaton,Qi Hao

Source: Nature communications
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition

Tuesday, September 20, 2022

Author(s): Russell A Judge,Janani Sridar,Kathryn Tunyasuvunakool,Rinku Jain,John C K Wang,Christna Ouch,Jun Xu,Amirhossein Mafi,Aaron H Nile,Clint Remarcik,Corey L Smith,Crystal Ghosh,Chen Xu,Vincent Stoll,John Jumper,Amoolya H Singh,Dan Eaton,Qi Hao

Source: Nature communications
Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism

Saturday, March 26, 2022

Author(s): Shawn B Egri,Christna Ouch,Hui-Ting Chou,Zhiheng Yu,Kangkang Song,Chen Xu,Kuang Shen

Source: Molecular cell
Quantitative structural analysis of influenza virus by cryo-electron tomography and convolutional neural networks

Tuesday, March 15, 2022

Author(s): Qiuyu J Huang,Kangkang Song,Chen Xu,Daniel N A Bolon,Jennifer P Wang,Robert W Finberg,Celia A Schiffer,Mohan Somasundaran

Source: Structure (London, England : 1993)
Comprehensive structure and functional adaptations of the yeast nuclear pore complex

Tuesday, January 04, 2022

Author(s): Christopher W Akey,Digvijay Singh,Christna Ouch,Ignacia Echeverria,Ilona Nudelman,Joseph M Varberg,Zulin Yu,Fei Fang,Yi Shi,Junjie Wang,Daniel Salzberg,Kangkang Song,Chen Xu,James C Gumbart,Sergey Suslov,Jay Unruh,Sue L Jaspersen,Brian T Chait,Andrej Sali,Javier Fernandez-Martinez,Steven J Ludtke,Elizabeth Villa,Michael P Rout

Source: Cell
Distinct allosteric mechanisms of first-generation MsbA inhibitors

Thursday, September 23, 2021

Author(s): François A Thélot,Wenyi Zhang,KangKang Song,Chen Xu,Jing Huang,Maofu Liao

Source: Science (New York, N.Y.)
Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins

Wednesday, August 04, 2021

Author(s): Stuti Sharma,Ruoyu Zhou,Li Wan,Shan Feng,KangKang Song,Chen Xu,Yanyan Li,Maofu Liao

Source: Nature communications
pH-Induced Conformational Changes of Human Bocavirus Capsids

Thursday, January 21, 2021

Author(s): Mengxiao Luo,Mario Mietzsch,Paul Chipman,Kangkang Song,Chen Xu,John Spear,Duncan Sousa,Robert McKenna,Maria Söderlund-Venermo,Mavis Agbandje-McKenna

Source: Journal of virology
Extensive ribosome and RF2 rearrangements during translation termination

Friday, September 13, 2019

Author(s): Egor Svidritskiy,Gabriel Demo,Anna B Loveland,Chen Xu,Andrei A Korostelev

Source: eLife
Structure of the Human Core Centromeric Nucleosome Complex

Tuesday, July 30, 2019

Author(s): Praveen Kumar Allu,Jennine M Dawicki-McKenna,Trevor Van Eeuwen,Moriya Slavin,Merav Braitbard,Chen Xu,Nir Kalisman,Kenji Murakami,Ben E Black

Source: Current biology : CB
Prion-like nanofibrils of small molecules (PriSM) selectively inhibit cancer cells by impeding cytoskeleton dynamics

Wednesday, August 27, 2014

Author(s): Yi Kuang,Marcus J C Long,Jie Zhou,Junfeng Shi,Yuan Gao,Chen Xu,Lizbeth Hedstrom,Bing Xu

Source: The Journal of biological chemistry

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BMB news as reported by the UMass Chan Communications Office

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December 09, 2024

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