Our long-term goal is to open new windows into the world of biology with the ability to see single molecules and their dynamics and macromolecular assemblies inside cells in unprecedented detail.

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About the UMass Chan Medical School Cryo-EM Facility

The Massachusetts Facility for High-Resolution Cryo-Electron Microscopy at UMass Chan Medical School was opened on Tuesday, Oct. 4, 2016. Since then, we have continued to lead the region in excellence and innovation. Learn more about our top-tier facility by watching the video below or checking out the Cryo-EM Core Facility website at this link.  

Commonly-Used Techniques

Cryo-EM -- Cryo-Electron Microscopy is a technique used in structural biology. It uses high speed electrons as source beam to obtain structural information of the biological system studied. Usually, the biological sample is embedded in vitrious ice by rapid freezing. The cryo sample is then observed and imaged in an electron microscope under liquid nitrogen temperature.

If you are new to Cryo-EM, you might find this short youtube video made by Gabriel Lander useful.