Publications

Soma-to-germline RNA communication

Sep 21, 2021

Author(s): Colin C Conine,Oliver J Rando

Source: Nature reviews. Genetics

Systematic evaluation of chromosome conformation capture assays

Sep 4, 2021

Author(s): Betul Akgol Oksuz,Liyan Yang,Sameer Abraham,Sergey V Venev,Nils Krietenstein,Krishna Mohan Parsi,Hakan Ozadam,Marlies E Oomen,Ankita Nand,Hui Mao,Ryan M J Genga,Rene Maehr,Oliver J Rando,Leonid A Mirn...

Source: Nature methods

Stability of the cytosine methylome during post-testicular sperm maturation in mouse

Mar 4, 2021

Author(s): Carolina Galan,Ryan W Serra,Fengyun Sun,Vera D Rinaldi,Colin C Conine,Oliver J Rando

Source: PLoS genetics

Deficient spermiogenesis in mice lacking Rlim

Feb 23, 2021

Author(s): Feng Wang,Maria Gracia Gervasi,Ana Bošković,Fengyun Sun,Vera D Rinaldi,Jun Yu,Mary C Wallingford,Darya A Tourzani,Jesse Mager,Lihua Julie Zhu,Oliver J Rando,Pablo E Visconti,Lara Strittmatter,Ingolf B...

Source: eLife

Sperm Head Preparation and Genetic Background Affect Caput Sperm ICSI Embryo Viability: Cauda-Enriched miRNAs Only Essential in Specific Conditions

Dec 22, 2020

Author(s): Colin C Conine,Fengyun Sun,Lina Song,Jaime A Rivera-Pérez,Oliver J Rando

Source: Developmental cell

A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization

Dec 5, 2020

Author(s): Romain Forey,Antoine Barthe,Mireille Tittel-Elmer,Maxime Wery,Marie-Bénédicte Barrault,Cécile Ducrot,Andrew Seeber,Nils Krietenstein,Ugo Szachnowski,Magdalena Skrzypczak,Krzysztof Ginalski,Maga Rowick...

Source: Molecular cell

METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth

Sep 14, 2020

Author(s): Valentina V Ignatova,Steffen Kaiser,Jessica Sook Yuin Ho,Xinyang Bing,Paul Stolz,Ying Xim Tan,Chee Leng Lee,Florence Pik Hoon Gay,Palma Rico Lastres,Raffaele Gerlini,Birgit Rathkolb,Antonio Aguilar-Pi...

Source: Science advances

Histone exchange is associated with activator function at transcribed promoters and with repression at histone loci

Sep 12, 2020

Author(s): Sari Kassem,Paolo Ferrari,Amanda L Hughes,Julien Soudet,Oliver J Rando,Michel Strubin

Source: Science advances

An atlas of cell types in the mouse epididymis and vas deferens

Jul 31, 2020

Author(s): Vera D Rinaldi,Elisa Donnard,Kyle Gellatly,Morten Rasmussen,Alper Kucukural,Onur Yukselen,Manuel Garber,Upasna Sharma,Oliver J Rando

Source: eLife

Mesoscale organization of the chromatin fiber

Apr 20, 2020

Author(s): Nils Krietenstein,Oliver J Rando

Source: Current opinion in genetics & development

The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs

Mar 29, 2020

Author(s): Valentina V Ignatova,Paul Stolz,Steffen Kaiser,Tobias H Gustafsson,Palma Rico Lastres,Adrián Sanz-Moreno,Yi-Li Cho,Oana V Amarie,Antonio Aguilar-Pimentel,Tanja Klein-Rodewald,Julia Calzada-Wack,Lore B...

Source: Genes & development

Ultrastructural Details of Mammalian Chromosome Architecture

Mar 28, 2020

Author(s): Nils Krietenstein,Sameer Abraham,Sergey V Venev,Nezar Abdennur,Johan Gibcus,Tsung-Han S Hsieh,Krishna Mohan Parsi,Liyan Yang,René Maehr,Leonid A Mirny,Job Dekker,Oliver J Rando

Source: Molecular cell

Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding

Mar 28, 2020

Author(s): Tsung-Han S Hsieh,Claudia Cattoglio,Elena Slobodyanyuk,Anders S Hansen,Oliver J Rando,Robert Tjian,Xavier Darzacq

Source: Molecular cell

Early life lessons: The lasting effects of germline epigenetic information on organismal development

Jan 25, 2020

Author(s): Carolina Galan,Marina Krykbaeva,Oliver J Rando

Source: Molecular metabolism

Transitions in paternal social status predict patterns of offspring growth and metabolic transcription

Dec 31, 2019

Author(s): Joseph W Cauceglia,Adam C Nelson,Nimrod D Rubinstein,Shweta Kukreja,Lynsey N Sasso,John A Beaufort,Oliver J Rando,Wayne K Potts

Source: Molecular ecology

Control of noncoding RNA production and histone levels by a 5' tRNA fragment

Dec 14, 2019

Author(s): Ana Boskovic,Xin Yang Bing,Ebru Kaymak,Oliver J Rando

Source: Genes & development

MicroRNAs Absent in Caput Sperm Are Required for Normal Embryonic Development

Jul 3, 2019

Author(s): Colin C Conine,Fengyun Sun,Lina Song,Jaime A Rivera-Pérez,Oliver J Rando

Source: Developmental cell

Profiling of Pluripotency Factors in Single Cells and Early Embryos

Apr 9, 2019

Author(s): Sarah J Hainer,Ana Bošković,Kurtis N McCannell,Oliver J Rando,Thomas G Fazzio

Source: Cell

tRNA Genes Affect Chromosome Structure and Function via Local Effects

Feb 6, 2019

Author(s): Omar Hamdani,Namrita Dhillon,Tsung-Han S Hsieh,Takahiro Fujita,Josefina Ocampo,Jacob G Kirkland,Josh Lawrimore,Tetsuya J Kobayashi,Brandon Friedman,Derek Fulton,Kenneth Y Wu,Răzvan V Chereji,Masaya Ok...

Source: Molecular and cellular biology

Paternal Exercise Improves Glucose Metabolism in Adult Offspring

Oct 23, 2018

Author(s): Kristin I Stanford,Morten Rasmussen,Lisa A Baer,Adam C Lehnig,Leslie A Rowland,Joseph D White,Kawai So,Ana Luisa De Sousa-Coelho,Michael F Hirshman,Mary-Elizabeth Patti,Oliver J Rando,Laurie J Goodyea...

Source: Diabetes

Transgenerational Epigenetic Inheritance

Aug 31, 2018

Author(s): Ana Bošković,Oliver J Rando

Source: Annual review of genetics

Small RNAs Gained during Epididymal Transit of Sperm Are Essential for Embryonic Development in Mice

Jul 31, 2018

Author(s): Colin C Conine,Fengyun Sun,Lina Song,Jaime A Rivera-Pérez,Oliver J Rando

Source: Developmental cell

Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm

Jul 31, 2018

Author(s): Upasna Sharma,Fengyun Sun,Colin C Conine,Brian Reichholf,Shweta Kukreja,Veronika A Herzog,Stefan L Ameres,Oliver J Rando

Source: Developmental cell

Effects of Larval Density on Gene Regulation in Caenorhabditis elegans During Routine L1 Synchronization

Apr 1, 2018

Author(s): Io Long Chan,Oliver J Rando,Colin C Conine

Source: G3 (Bethesda, Md.)

Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs

Dec 28, 2017

Author(s): Feng Wang,Kurtis N McCannell,Ana Bošković,Xiaochun Zhu,JongDae Shin,Jun Yu,Judith Gallant,Meg Byron,Jeanne B Lawrence,Lihua J Zhu,Stephen N Jones,Oliver J Rando,Thomas G Fazzio,Ingolf Bach

Source: Cell reports

Transcriptome-wide Analysis of Roles for tRNA Modifications in Translational Regulation

Dec 5, 2017

Author(s): Hsin-Jung Chou,Elisa Donnard,H Tobias Gustafsson,Manuel Garber,Oliver J Rando

Source: Molecular cell

A synthetic biology approach to probing nucleosome symmetry

Sep 13, 2017

Author(s): Yuichi Ichikawa,Caitlin F Connelly,Alon Appleboim,Thomas Cr Miller,Hadas Jacobi,Nebiyu A Abshiru,Hsin-Jung Chou,Yuanyuan Chen,Upasna Sharma,Yupeng Zheng,Paul M Thomas,Hsuiyi V Chen,Vineeta Bajaj,Chris...

Source: eLife

LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo

Aug 29, 2017

Author(s): Joanna W Jachowicz,Xinyang Bing,Julien Pontabry,Ana Bošković,Oliver J Rando,Maria-Elena Torres-Padilla

Source: Nature genetics

Metabolic Inputs into the Epigenome

Mar 9, 2017

Author(s): Upasna Sharma,Oliver J Rando

Source: Cell metabolism

Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring

Feb 15, 2017

Author(s): Markus P Vallaster,Shweta Kukreja,Xin Y Bing,Jennifer Ngolab,Rubing Zhao-Shea,Paul D Gardner,Andrew R Tapper,Oliver J Rando

Source: eLife

DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells

Nov 17, 2016

Author(s): Sarah J Hainer,Kurtis N McCannell,Jun Yu,Ly-Sha Ee,Lihua J Zhu,Oliver J Rando,Thomas G Fazzio

Source: eLife

Micro-C XL: assaying chromosome conformation from the nucleosome to the entire genome

Nov 8, 2016

Author(s): Tsung-Han S Hsieh,Geoffrey Fudenberg,Anton Goloborodko,Oliver J Rando

Source: Nature methods

Regulation of X-linked gene expression during early mouse development by Rlim

Sep 20, 2016

Author(s): Feng Wang,JongDae Shin,Jeremy M Shea,Jun Yu,Ana Bošković,Meg Byron,Xiaochun Zhu,Alex K Shalek,Aviv Regev,Jeanne B Lawrence,Eduardo M Torres,Lihua J Zhu,Oliver J Rando,Ingolf Bach

Source: eLife

Dynamics of Nucleosome Positioning Maturation following Genomic Replication

Aug 30, 2016

Author(s): Pauline Vasseur,Saphia Tonazzini,Rahima Ziane,Alain Camasses,Oliver J Rando,Marta Radman-Livaja

Source: Cell reports

Intergenerational Transfer of Epigenetic Information in Sperm

Jan 24, 2016

Author(s): Oliver J Rando

Source: Cold Spring Harbor perspectives in medicine

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

Jan 2, 2016

Author(s): Upasna Sharma,Colin C Conine,Jeremy M Shea,Ana Boskovic,Alan G Derr,Xin Y Bing,Clemence Belleannee,Alper Kucukural,Ryan W Serra,Fengyun Sun,Lina Song,Benjamin R Carone,Emiliano P Ricci,Xin Z Li,Lucas ...

Source: Science (New York, N.Y.)

Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome

Dec 26, 2015

Author(s): Jeremy M Shea,Ryan W Serra,Benjamin R Carone,Hennady P Shulha,Alper Kucukural,Michael J Ziller,Markus P Vallaster,Hongcang Gu,Andrew R Tapper,Paul D Gardner,Alexander Meissner,Manuel Garber,Oliver J R...

Source: Developmental cell

Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis

Nov 21, 2015

Author(s): Mayuri Rege,Vidya Subramanian,Chenchen Zhu,Tsung-Han S Hsieh,Assaf Weiner,Nir Friedman,Sandra Clauder-Münster,Lars M Steinmetz,Oliver J Rando,Laurie A Boyer,Craig L Peterson

Source: Cell reports

R loops regulate promoter-proximal chromatin architecture and cellular differentiation

Nov 10, 2015

Author(s): Poshen B Chen,Hsiuyi V Chen,Diwash Acharya,Oliver J Rando,Thomas G Fazzio

Source: Nature structural & molecular biology

Epigenomics and the structure of the living genome

Oct 3, 2015

Author(s): Nir Friedman,Oliver J Rando

Source: Genome research

Comparative Genomics Reveals Chd1 as a Determinant of Nucleosome Spacing in Vivo

Jul 16, 2015

Author(s): Amanda L Hughes,Oliver J Rando

Source: G3 (Bethesda, Md.)

Mapping Nucleosome Resolution Chromosome Folding in Yeast by Micro-C

Jun 30, 2015

Author(s): Tsung-Han S Hsieh,Assaf Weiner,Bryan Lajoie,Job Dekker,Nir Friedman,Oliver J Rando

Source: Cell

Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal

Apr 22, 2015

Author(s): Rubing Zhao-Shea,Steven R DeGroot,Liwang Liu,Markus Vallaster,Xueyan Pang,Qin Su,Guangping Gao,Oliver J Rando,Gilles E Martin,Olivier George,Paul D Gardner,Andrew R Tapper

Source: Nature communications

I'm eating for two: parental dietary effects on offspring metabolism

Mar 28, 2015

Author(s): Oliver J Rando,Rebecca A Simmons

Source: Cell

High-resolution chromatin dynamics during a yeast stress response

Mar 25, 2015

Author(s): Assaf Weiner,Tsung-Han S Hsieh,Alon Appleboim,Hsiuyi V Chen,Ayelet Rahat,Ido Amit,Oliver J Rando,Nir Friedman

Source: Molecular cell

Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF

Feb 19, 2015

Author(s): Sarah J Hainer,Weifeng Gu,Benjamin R Carone,Benjamin D Landry,Oliver J Rando,Craig C Mello,Thomas G Fazzio

Source: Genes & development

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

Aug 8, 2014

Author(s): Ozlem Yildirim,Jui-Hung Hung,Ryan J Cedeno,Zhiping Weng,Christopher J Lengner,Oliver J Rando

Source: PLoS genetics

High-resolution mapping of chromatin packaging in mouse embryonic stem cells and sperm

Jul 8, 2014

Author(s): Benjamin R Carone,Jui-Hung Hung,Sarah J Hainer,Min-Te Chou,Dawn M Carone,Zhiping Weng,Thomas G Fazzio,Oliver J Rando

Source: Developmental cell

Father-son chats: inheriting stress through sperm RNA

Jun 5, 2014

Author(s): Upasna Sharma,Oliver J Rando

Source: Cell metabolism

Mechanisms underlying nucleosome positioning in vivo

Apr 8, 2014

Author(s): Amanda L Hughes,Oliver J Rando

Source: Annual review of biophysics

Feedback control of Set1 protein levels is important for proper H3K4 methylation patterns

Mar 12, 2014

Author(s): Luis M Soares,Marta Radman-Livaja,Sherry G Lin,Oliver J Rando,Stephen Buratowski

Source: Cell reports

A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme

Apr 13, 2013

Author(s): Shinya Watanabe,Marta Radman-Livaja,Oliver J Rando,Craig L Peterson

Source: Science (New York, N.Y.)

Painting by numbers: increasing the parts list for chromatin domains

Feb 27, 2013

Author(s): Hsiuyi V Chen,Oliver J Rando

Source: Molecular cell

Daddy issues: paternal effects on phenotype

Nov 13, 2012

Author(s): Oliver J Rando

Source: Cell

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

Sep 8, 2012

Author(s): Jie Wang,Jiali Zhuang,Sowmya Iyer,XinYing Lin,Troy W Whitfield,Melissa C Greven,Brian G Pierce,Xianjun Dong,Anshul Kundaje,Yong Cheng,Oliver J Rando,Ewan Birney,Richard M Myers,William S Noble,Michael...

Source: Genome research

A functional evolutionary approach to identify determinants of nucleosome positioning: a unifying model for establishing the genome-wide pattern

Aug 14, 2012

Author(s): Amanda L Hughes,Yi Jin,Oliver J Rando,Kevin Struhl

Source: Molecular cell

A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast

Jul 19, 2012

Author(s): Marta Radman-Livaja,Tiffani K Quan,Lourdes Valenzuela,Jennifer A Armstrong,Tibor van Welsem,Taesoo Kim,Laura J Lee,Stephen Buratowski,Fred van Leeuwen,Oliver J Rando,Grant A Hartzog

Source: PLoS genetics

Rewriting the epigenome

Jun 26, 2012

Author(s): Benjamin R Carone,Oliver J Rando

Source: Cell

NURDs are required for diversity

May 15, 2012

Author(s): Thomas G Fazzio,Oliver J Rando

Source: The EMBO journal

Genome-wide identification and characterization of replication origins by deep sequencing

Apr 26, 2012

Author(s): Jia Xu,Yoshimi Yanagisawa,Alexander M Tsankov,Christopher Hart,Keita Aoki,Naveen Kommajosyula,Kathleen E Steinmann,James Bochicchio,Carsten Russ,Aviv Regev,Oliver J Rando,Chad Nusbaum,Hironori Niki,Pa...

Source: Genome biology

Combinatorial complexity in chromatin structure and function: revisiting the histone code

Mar 24, 2012

Author(s): Oliver J Rando

Source: Current opinion in genetics & development

Chromatin and transcription in yeast

Feb 21, 2012

Author(s): Oliver J Rando,Fred Winston

Source: Genetics

Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells

Dec 27, 2011

Author(s): Ozlem Yildirim,Ruowang Li,Jui-Hung Hung,Poshen B Chen,Xianjun Dong,Ly-Sha Ee,Zhiping Weng,Oliver J Rando,Thomas G Fazzio

Source: Cell

Genome-wide measurement of histone H3 replacement dynamics in yeast

Aug 25, 2011

Author(s): Oliver J Rando

Source: Methods in molecular biology (Clifton, N.J.)

Patterns and mechanisms of ancestral histone protein inheritance in budding yeast

Jun 14, 2011

Author(s): Marta Radman-Livaja,Kitty F Verzijlbergen,Assaf Weiner,Tibor van Welsem,Nir Friedman,Oliver J Rando,Fred van Leeuwen

Source: PLoS biology

Dynamics of Sir3 spreading in budding yeast: secondary recruitment sites and euchromatic localization

Feb 22, 2011

Author(s): Marta Radman-Livaja,Giulia Ruben,Assaf Weiner,Nir Friedman,Rohinton Kamakaka,Oliver J Rando

Source: The EMBO journal

Global regulation of H2A.Z localization by the INO80 chromatin-remodeling enzyme is essential for genome integrity

Jan 19, 2011

Author(s): Manolis Papamichos-Chronakis,Shinya Watanabe,Oliver J Rando,Craig L Peterson

Source: Cell

Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals

Dec 25, 2010

Author(s): Benjamin R Carone,Lucas Fauquier,Naomi Habib,Jeremy M Shea,Caroline E Hart,Ruowang Li,Christoph Bock,Chengjian Li,Hongcang Gu,Phillip D Zamore,Alexander Meissner,Zhiping Weng,Hans A Hofmann,Nir Friedm...

Source: Cell