Publications

MAPK modulation of yeast pheromone signaling output and the role of phosphorylation sites in the scaffold protein Ste5.

Author(s): Winters MJ, Pryciak PM

CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5.

Author(s): Repetto MV, Winters MJ, Bush A, Reiter W, Hollenstein DM, Ammerer G, Pryciak PM, Colman-Lerner A

Analysis of the thresholds for transcriptional activation by the yeast MAP kinases Fus3 and Kss1.

Author(s): Winters MJ, Pryciak PM

A docking interface in the cyclin Cln2 promotes multi-site phosphorylation of substrates and timely cell-cycle entry.

Author(s): Bhaduri S, Valk E, Winters MJ, Gruessner B, Loog M, Pryciak PM

Regulation of cyclin-substrate docking by a G1 arrest signaling pathway and the Cdk inhibitor Far1.

Author(s): Pope PA, Bhaduri S, Pryciak PM

Functional overlap among distinct G1/S inhibitory pathways allows robust G1 arrest by yeast mating pheromones.

Author(s): Pope PA, Pryciak PM

Cyclin-specific docking motifs promote phosphorylation of yeast signaling proteins by G1/S Cdk complexes.

Author(s): Bhaduri S, Pryciak PM

Designing new cellular signaling pathways.

Author(s): Pryciak PM

Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade.

Author(s): Takahashi S, Pryciak PM

Systems biology. Customized signaling circuits.

Author(s): Pryciak PM

Distinct roles for two Galpha-Gbeta interfaces in cell polarity control by a yeast heterotrimeric G protein.

Author(s): Strickfaden SC, Pryciak PM

Identification of novel membrane-binding domains in multiple yeast Cdc42 effectors.

Author(s): Takahashi S, Pryciak PM

A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway.

Author(s): Strickfaden SC, Winters MJ, Ben-Ari G, Lamson RE, Tyers M, Pryciak PM

Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity.

Author(s): Lamson RE, Takahashi S, Winters MJ, Pryciak PM

A membrane binding domain in the ste5 scaffold synergizes with gbetagamma binding to control localization and signaling in pheromone response.

Author(s): Winters MJ, Lamson RE, Nakanishi H, Neiman AM, Pryciak PM

Interaction with the SH3 domain protein Bem1 regulates signaling by the Saccharomyces cerevisiae p21-activated kinase Ste20.

Author(s): Winters MJ, Pryciak PM

Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.

Author(s): Lamson RE, Winters MJ, Pryciak PM

Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins.

Author(s): Harris K, Lamson RE, Nelson B, Hughes TR, Marton MJ, Roberts CJ, Boone C, Pryciak PM

MAP kinases bite back.

Author(s): Pryciak PM

Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae.

Author(s): Moskow JJ, Gladfelter AS, Lamson RE, Pryciak PM, Lew DJ

The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating.

Author(s): Butty AC, Pryciak PM, Huang LS, Herskowitz I, Peter M

Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway.

Author(s): Pryciak PM, Huntress FA

AKR1 encodes a candidate effector of the G beta gamma complex in the Saccharomyces cerevisiae pheromone response pathway and contributes to control of both cell shape and signal transduction.

Author(s): Pryciak PM, Hartwell LH

Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients.

Author(s): Dorer R, Pryciak PM, Hartwell LH

Retroviral integration machinery as a probe for DNA structure and associated proteins.

Author(s): Müller HP, Pryciak PM, Varmus HE

Simian virus 40 minichromosomes as targets for retroviral integration in vivo.

Author(s): Pryciak PM, Müller HP, Varmus HE

Fv-1 restriction and its effects on murine leukemia virus integration in vivo and in vitro.

Author(s): Pryciak PM, Varmus HE

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection.

Author(s): Pryciak PM, Varmus HE

Retroviral integration into minichromosomes in vitro.

Author(s): Pryciak PM, Sil A, Varmus HE

The design, synthesis, and crystallization of an alpha-helical peptide.

Author(s): Eisenberg D, Wilcox W, Eshita SM, Pryciak PM, Ho SP, DeGrado WF

Publications

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