Xin Yang, Ph.D.
| Instructor (Gregory Lab) |  |
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| Ph.D.: University of Chinese Academy of Sciences | ||
| Postdoctoral research: Harvard Medical School, Boston Children's Hospital | ||
| Office: | UMass Chan Medical School 364 Plantation Street, LRB 660D Worcester, MA 01605 |
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Research
My research integrates high-throughput functional screens with multi-omics sequencing to decode the regulatory roles of the epitranscriptome in cancer. Positioned at the intersection of RNA biology and genomics, my work focuses on:
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- tRNA Biology: Developing innovative genomic strategies to achieve single-tRNA-gene resolution, overcoming technical barriers to reveal how tRNA dysregulation drives translational reprogramming in disease.
- RNA Modifications: Characterizing the dynamic regulation of m³C modifications, uncovering how these epitranscriptomic marks drive cancer progression and define new therapeutic vulnerabilities.