Yoshiko Usami, Ph.D.
| Instructor |  |
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| Ph.D.: 1993, Gifu Pharmaceutical University | ||
| Postdoctoral research: UMass Chan Medical School | ||
| Office: | UMass Chan Medical School 364 Plantation Street, LRB-570-J Worcester, MA 01605 |
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| Phone: | 508-856-2832 | |
| Email: | Yoshiko.Usami@umassmed.edu | |
Research
My research program focuses on the discovery of antiviral host proteins that restrict HIV-1 infectivity. Through my work I have discovered two host cell proteins, SERINC3 and SERINC5, that are counteracted by the HIV-1 protein Nef. Furthermore, I have shown that an intracellular loop region of SERINC5 plays an important role in its sensitivity to Nef.