Publications

Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease Flynn, Julia M; Huang, Qiu Yu J; Zvornicanin, Sarah N; Schneider-Nachum, Gila; Shaqra, Ala M; Yilmaz, Nese K...

FruitFire: a luciferase based on a fruit fly metabolic enzyme [preprint] Adams, Spencer T; Zephyr, Jacqueto; Bohn, Markus F; Schiffer, Celia A; Miller, Stephen C Firefly luciferase is homologous to fa...

HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues Lockbaum, Gordon J; Rusere, Linah N; Henes, M...

Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses Zvornicanin, Sarah N; Shaqra, Ala M; Huang, Qiuyu J; Ornelas, Elizabeth; Moghe, Mallika; Knapp, Mark; Moquin, St...

Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance Spielvogel, Ean; Lee, Sook-Kyung; Zhou, Shuntai; Lockbaum, Gordon J;...

Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans Peterson, Nicholas D; Tse, Samantha Y; Huang, Qiuyu Judy; Wa...

Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease Zephyr, Jacqueto; Rao, Desaboini Nageswara; Johnson, Colby; Shaqra, Ala M; Nalivaika, Ellen A; Jordan, Aria; Kurt Yilmaz, Ne...

Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state Maiti, Atanu; Hedger, Adam K; Myint, Wazo; Balachandran, Va...

Dual Inhibitors of Main Protease (M) and Cathepsin L as Potent Antivirals against SARS-CoV2 Mondal, Santanu; Chen, Yongzhi; Lockbaum, Gordon J; Sen, Sudeshna; Chaudhuri, Sauradip; Reyes, Archie C; Lee...

Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants Li, Qi; Humphries, Fiachra; Girardin, Roxie C; Wallace, Aaron; Ejemel, ...