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Comprehensive scientific and clinical solutions to address the critical challenge of drug resistance by prioritization in drug design and therapeutic strategies.

 

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  • Medicines Designed to Last

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  • Uncovering Pathways to Resistance in cancer

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  • Chemo Chainsaw

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  • Overcoming Therapeutic Resistance in Pancreatic Cancer

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  • Designed Biologics as Antivirals to avoid Drug Resistance

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  • Newest Drugs for the Oldest Parasites

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  • Thwarting Antibiotic Resistance in Psuedonomas Aerginosa

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  • Using Structural Biology to Tackle Antibiotic Resistance

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  • Modifying Bacterial Behavior to Avoid Antibiotic Resistance

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  • How to Discover New Antibiotics by Getting Bacteria to “Talk” to Each Other

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  • How I Stopped Worrying and Learned to Love the Microbiome

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  • Bacteria Infection of Cancer Tumors – The Hidden Passengers we Ignored for too Long

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  • Preventing Antibiotic Resistance by Blocking Evolution

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Latest News

Getting Results…
  • PhD student Megan Honeywell receives prestigious Ruth L. Kirschstein Predoctoral award
    Research News

    PhD student Megan Honeywell receives prestigious Ruth L. Kirschstein Predoctoral award

    In her preliminary studies, PhD student Megan Honeywell has found that cells can trigger a cell death even when they do not have the p53 protein, the so-called “guardian of the genome.”

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  • Roberto Caricchio, Michelle Kelliher and Celia Schiffer appointed to endowed chairs
    Community News, Media

    Robert Caricchio, Michelle Kelliher and Celia Schiffer appointed to endowed chairs

    UMass Chan faculty in rheumatology, biochemistry & molecular biotechnology and cancer biology are being supported by endowments.

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  • Communicating science: Read Pukkila-Worley studies antibiotic resistance in bacterial infection
    Media, Research News

    Communicating science: Read Pukkila-Worley studies antibiotic resistance in bacterial infection

    Read Pukkila-Worley, MD, is a physician-scientist researching how bacteria cause disease and how the immune system detects infection.

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  • Communicating science: Raffi Van Aroian studies parasites in humans
    Media, Research News

    Communicating science: Raffi Van Aroian studies parasites in humans

    Raffi Van Aroian, PhD, studies intestinal parasitic nematodes, or worms, which can seriously impact children. To combat drug resistance, he and colleague Gary R. Ostroff, PhD, are working on a new type of treatment.

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  • UMass Chan researcher explains convalescent plasma’s potential as COVID-19 treatment
    Media, Research News

    UMass Chan researcher explains convalescent plasma’s potential as COVID-19 treatment

    Jonathan Gerber, MD, discusses a therapy that has been around for at least a century and how it has helped in the COVID-19 pandemic.

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  • Communicating science: Yang Wang discusses drug resistance in COVID-19
    Media, Research News

    Communicating science: Yang Wang discusses drug resistance in COVID-19

    Yang Wang, MD, PhD, leads a team of scientists working to discover and develop antibody-based medicines for infectious diseases and understand drug resistance in those medicines.

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  • UMass Cancer Walk and Run chosen as best local fundraiser event by WBJ readers
    Community News

    UMass Cancer Walk and Run chosen as best local fundraiser event by WBJ readers

    Worcester Business Journal readers have chosen the UMass Cancer Walk and Run as the best nonprofit fundraiser event in Central Massachusetts.

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  • Jason Shohet receives second Hyundai Hope on Wheels grant
    Research News

    Jason Shohet receives second Hyundai Hope on Wheels grant

    Hyundai Hope on Wheels has awarded Jason Shohet, MD, PhD, a second $300,000 Scholar Hope Grant to continue his research on neuroblastoma, a deadly cancer in children that affects the peripheral nervous system.

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  • Early use of convalescent plasma treatment for COVID-19 helps avoid hospitalization
    Research News

    Early use of convalescent plasma treatment for COVID-19 helps avoid hospitalization

    Results of a clinical trial led by Jonathan M. Gerber, MD, suggest that early use of convalescent plasma treatment for COVID-19 helps avoid hospitalization.

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  • Communicating science: Brian Lewis discusses overcoming therapeutic resistance in pancreatic cancer
    Research News

    Communicating science: Brian Lewis discusses overcoming therapeutic resistance in pancreatic cancer

    Brian Lewis, PhD, is studying therapeutic resistance in pancreatic cancer cells, hoping to change the grim statistics for patients diagnosed with pancreatic cancer.

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