Representative Publications

• Gao KM, Chiang K, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A. (2023) Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs. bioRxiv. 2023.07.27.550897
  
  
• Gao KM, Nündel K, Chiang K, Yin X, Utz PJ, Fitzgerald K, Marshak-Rothstein A. (2023) Activation of Autoreactive Lymphocytes in the Lung by STING Gain-of-function Mutation Radioresistant Cells. bioRxiv. 2023.07.28.551002. 
  
  
• Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, Moody KL, Nündel K, Marshak-Rothstein A, van der Made CI, Hoischen A, Hayward A, Rossato M, Radstake TRDJ, Cunningham-Rundles C, Ryu C, Herzog EL, Barrat FJ, Meffre E. (2023) TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance. J Exp Med. 220(12):e20230944
  
  
• Gao KM, Motwani M, Tedder T, Marshak-Rothstein A, Fitzgerald KA. (2022) Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice. Proc Natl Acad Sci U S A. 119(25):e2202327119.
  
  
• Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. (2021) Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 54(6):1137-1153. 
  
  
• Gregory-Ksander M, Marshak-Rothstein A. (2021) The FasLane to ocular pathology-metalloproteinase cleavage of membrane-bound FasL determines FasL function. J Leukoc Biol. Epub ahead of print.
  
  
• Pawaria S, Nündel K, Gao KM, Moses S, Busto P, Holt K, Sharma RB, Brehm MA, Gravallese EM, Socolovsky M, Christ A, Marshak-Rothstein A. (2020) Role of Interferon-γ-Producing Th1 Cells in a Murine Model of Type I Interferon-Independent Autoinflammation Resulting from DNase II Deficiency. Arthritis Rheumatol. 72:359-370. 
  
  
• Nündel K, Mande P, Moses SL, Busto P, Cullen JL, Schmidt MR, Shlomchik MJ, Woodland RT, Marshak-Rothstein A. (2019) Cross-Reactive Antigen Expressed by B6 Splenocytes Drives Receptor Editing and Marginal Zone Differentiation of IgG2a-Reactive AM14 Vκ8 B Cells. J Immunol. 203:2055-2062. 
  
  
• Motwani M, Pawaria S, Bernier J, Moses S, Henry K, Fang T, Burkly L, Marshak- Rothstein A, and Fitzgerald KA. (2019) Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models. PNAS 16:7941-50. 
  
  
• Gregory-Ksander M, Perez VL, Marshak-Rothstein A, Ksander BR. (2019) Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis. Exp Eye Res. 179:47-54. 
  
  

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