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Welcome to the Program in Systems Biology

Our program aims to explore the mechanisms and principles of biological complexity. This is an exciting time for systems biology, with rapid technological advances in many fields including genomics, computational biology, imaging, mass spectroscopy and bioinformatics. Research in the program develops and leverages technological breakthroughs in these areas to explore the biology of complex systems. Today’s scientific research in general, and systems biology in particular, is increasingly multi-disciplinary. Therefore, we aim to create an intellectually diverse environment where combining different fields is encouraged and where students, post-doctoral fellows and faculty from different backgrounds work together in a collegial and interactive atmosphere.

Please browse through our website to learn more about our ongoing research, find recent publications and news items, upcoming speakers in our seminar series, or visit us at the UMass, Worcester campus.

A.J. Marian Walhout, PhD & Job Dekker, PhD, Co-Directors


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Amir Mitchell receives the Maximizing Investigators' Research Award from the National Institute of General Medical Sciences to support research into cellular decoding of signaling dynamics
OCT 9, 2019

Job Dekker receives the Chancellor’s Medal for Distinguished Scholarship at the 2019 Convocation
SEP 13, 2019

Amir Mitchell lab engages high school classes in superbug research via online portal
MAY 14, 2019

Amir Mitchell, PhD

The Dekker Lab and colleagues develop new model to examine large mutations in cells published in Nature Genetics
SEP 11, 2018

Ben Landry, Mike Lee and colleagues publish their findings on the diversity in tumor–stromal cell interactions that modulate chemotherapeutic drug sensitivity in Molecular Systems Biology
JUN 28, 2018

PSB faculty receive award for outstanding contribution to curricular development for the Systems and Computational Biology course
APR 19, 2018

Job Dekker receives 2018 Edward Novitski Prize from the Genetics Society of America
FEB 9, 2018

Job Dekker, PhD

Johan Gibcus, Job Dekker and colleagues publish their research on a pathway for mitotic chromosome formation in Science
JAN 18, 2018

Job Dekker appointed inaugural Joseph J. Byne Chair in Biomedical Research
JUL 17, 2017

Aurian García-González, Marian Walhout, and colleagues publish study in Cell showing that bacteria modulate host chemotherapeutic drug responses
APR 21, 2017

Marian Walhout, PhD, & Aurian Garcia-Gonzalez

Rob Brewster and colleagues publish a kinetic model of transcription that incorporates the interplay between transcription factor copy number and its binding sites in PLoS Computational Biology
APR 17, 2017