Publications

Selection of lab publications:

  1. Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, Caffrey DR, Fitzgerald KA. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 2016 Jun 16;165(7):1672-85. 
  2. Sharma S, Campbell AM, Chan J, Schattgen SA, Orlowski GM, Nayar R, Huyler AH,  Nundel K, Mohan C, Berg LJ, Shlomchik MJ, Marshak-Rothstein A, Fitzgerald KA. Suppression of systemic autoimmunity by the innate immune adaptor STING. Proc Natl  Acad Sci U S A 2015 112: E710-7
  3. Kalantari P, Deoliveira RB, Chan J, Corbett Y, Rathinam V, Stutz A, Latz E, Gazzinelli  RT, Golenbock DT, Fitzgerald KA.  Dual Engagement of the NLRP3 and AIM2  Inflammasomes by Plasmodium-Derived Hemozoin and DNA during Malaria. Cell Rep 2014.6:  196-210
  4. Carpenter S, Aiello D, Atianand MK, Ricci EP, Gandhi P, Hall LL, Byron M, Monks B, Henry-Bezy M, Lawrence JB, O'Neill LA, Moore MJ, Caffrey DR, Fitzgerald KA. A long noncoding RNA mediates  both activation and repression of immune response genes. Science 2013 341: 789-92
  5. Rathinam VA, Vanaja SK, Waggoner L, Sokolovska A, Becker C, Stuart LM, Leong JM, Fitzgerald KA. TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.  Cell 2013 150: 606-19
  6. Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG,  Ganesan S, Latz E, Hornung V, Vogel SN, Szomolanyi-Tsuda E, Fitzgerald KA. The AIM2  inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol 2010 11:  395-402
  7. Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.  Nature 2009. 458: 514-8