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Mehdi Rashighi

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Mehdi Rashighi, MD

Assistant Professor of Dermatology

Specialties
Dermatology

Clinical Interests
Alopecia Areata
Autoimmune hair loss
Connective Tissue Diseases
Cutaneous Lupus
Dermatomyositis
En Coup De Sabre
Eosinophilic Fasciitis
Frontal Fibrosing Alopecia
Hemifacial Atrophy
Lichen Planopilaris
Medical Dermatology
Morphea
Scleroderma
Systemic Sclerosis
Vitiligo

Education

Medical School
Tehran University of Medical Sciences, 2004, Tehran, Iran

Internship
Internal Medicine, University of Massachusetts Medical School, 2013-2014

Residency
Dermatology, University of Massachusetts Medical School, 2016-2019

Certification and Licensure
Dermatology, 2019
Full Massachusetts Medical License, 2019

Research Training
Translational Dermatology, University of Massachusetts Medical School, 2014-2016
Basic Immunodermatology, University of Massachusetts Medical School, 2011-2014

Memberships in Professional Societies
American Medical Association
Society for Investigative Dermatology
American Academy of Dermatology
Rheumatologic Dermatology Society
Pediatric Dermatology Research Alliance
Childhood Arthritis and Rheumatology Research Alliance
International Myositis Assessment & Clinical Studies Group
CureJM Foundation
New England Dermatological Society

Ad Hoc Reviewer
eLife
Science Advances
Frontiers in Immunology
Journal of Investigative Dermatology
Journal of the American Academy of Dermatology
JAMA Dermatology
Pigment Cell & Melanoma Research
British Journal of Dermatology
Experimental Dermatology
Archives of Dermatological Research

Awards
Travel Fellowship Award, Naples, U.S., Dermatology Foundation Clinical Symposia, 2019
Travel Fellowship Award, Vienna, Austria, Inflammatory Skin Disease Summit, 2018
Travel Fellowship Award, Las Vegas, U.S., Rising Derm Stars, Fall Clinical Dermatology Conference, 2018
Travel Fellowship Award, Tehran, Iran, Spring Continental Congress of Dermatology, 2018
Travel Fellowship Award, New York, U.S., Inflammatory Skin Disease Summit, 2016
Travel Fellowship Award, Edinburgh, Scotland, International Investigative Dermatology, 2014
Albert M. Kligman Travel Fellowship Award, Raleigh, U.S., Society for Investigative Dermatology, 2012
IVLP Travel Fellowship Award, Washington DC, U.S. Department of State, 2006
Travel Fellowship Award, Washington DC, U.S., Aspen Institute, 2006

Publications
Richmond JM, Strassner JP, Rashighi M, Agarwal P, Garg M, Essien KI, Pell LP, Harris JE. Resident memory and recirculating memory T cells cooperate to maintain disease in a mouse model of vitiligo. Journal of Investigative Dermatology. 2018 Nov 10. [Epub ahead of print]

Rashighi M, Harris JE. Vitiligo Pathogenesis and Emerging Treatments. Dermatologic Clinics. 2017 Apr;35(2):257-265.

Rashighi M, Harris JE. Sampling serum in patients with vitiligo to measure disease activity in the skin. JAMA dermatology. 2016 Nov; 152(11): 1187-1188.

Rork JF, Rashighi M, Harris JE Understanding autoimmunity of vitiligo and alopecia areata. Current Opinions in Pediatrics. 2016 Aug; 28(4): 463-469.

Rashighi M, Harris JE. Serum chemokines herald disease activity and treatment response in vitiligo patients. British Journal of Dermatology. 2016 Jun; 174(6): 1190-1191.

Strassner JP, Rashighi M, Harris JE. Melanocytes in psoriasis: convicted culprit or bullied bystander? Journal Pigment cell & melanoma research. 2016 May; 29(3): 261-263

Harris JE, Rashighi M, Nguyen N, Jabbari A, Ulerio G, Clynes R, Christiano AM, Mackay-Wiggan J. Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA). Journal of the American Academy of Dermatology. 2016 Feb; 74(2): 370-371.

Rashighi M, Harris JE. Interfering with the IFN-γ/CXCL10 pathway to develop new targeted treatments for vitiligo. Annals of translational medicine. 2015 Dec; 3(21): 343.

Agarwal P, Rashighi M, Essien KI, Richmond JM, Randall L, Pazoki-Toroudi H, Hunter CA, Harris JE. Simvastatin prevents and reverses depigmentation in a mouse model of vitiligo. Journal of Investigative Dermatology. 2015 Apr; 135 (4): 1080-1088.

Rashighi M, Agarwal P, Richmond JM, Harris TH, Dresser K, Su MW, Zhou Y, Deng A, Hunter CA, Luster AD, Harris JE. CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo. Science Translational Medicine. 2014 Feb; 6(223): 223ra23.

Malhotra N, Narayan K, Cho OH, Sylvia KE, Yin C, Melichar H, Rashighi M, Lefebvre V, Harris JE, Berg LJ, Kang J; Immunological Genome Project Consortium. A network of high-mobility group box transcription factors programs innate interleukin-17 production.
Immunity. 2013 Apr; 38(4): 681–693.

Pazoki-Toroudi H, Babakoohi S, Nilforoushzadeh MA, Nassiri-Kashani M, Shizarpour M, Ajami M, Habibey R, Sadr B, Rashighi M, Firooz A. Therapeutic effects of minoxidil high extra combination therapy in patients with androgenetic alopecia. Skinmed. 2012 Sep;10(5): 276-282.

Davoudi SM, Rashighi M, Gorouhi F, Karimi Zarchi AA, Nasiri Kashani M, Dowlati Y, Firooz A. Patch testing in Iranian patients: A ten-year experience. Indian Journal of Dermatology. 2011 Mar; 51(4): 250-254.

Davoudi SM, Sadr B, Hayatbakhsh MR, Keshavarz S, Shohrati M, Naghizadeh MM, Babakoohi S, Rashighi M, Firooz A. Comparative study of skin sebum and elasticity level in patients with sulfur mustard-induced dermatitis and healthy controls. Skin Research and Technology. 2010 May; 16(2): 237-242.

Davoudi SM, Keshavarz S, Sadr B, Shohrati M, Naghizadeh MM, Farsinejad K, Rashighi M, Zartab H, Firooz A. Comparison of Skin Erythema and Melanin Level in Sulfur Mustard Induced Chronic Skin Lesions and Normal Skin. Iranian Journal of Dermatology. 2009 Jan; 11(4): 151-154.

Davoudi SM, Keshavarz S, Sadr B, Shohrati M, Naghizadeh MM, Farsinejad K, Rashighi M, Zartab H, Firooz A. Skin hydration and transepidermal water loss in patients with a history of sulfur mustard contact: a case-control study. Journal of European Academy of Dermatology and Venereology. 2009 Aug; 23(8): 940(8): 940-944.

Davoudi SM, Behnia F, Gorouhi F, Keshavarz S, Nassiri Kashani M, Rashighi M, Firooz A. Comparison of long-pulsed alexandrite and Nd:YAG lasers, individually and in combination, for leg hair reduction: an assessor-blinded, randomized trial with 18 months of follow-up. Archives of Dermatology. 2008 Oct; 144(10): 1323-1327.

Firooz A, Farsi N, Rashighi M, Gorouhi F. Pigmented Bowen's disease of the finger mimicking malignant melanoma. Archives of Iranian Medicine. 2007 Apr; 10(2): 255-257.

Firooz A, Gorouhi F, Davari P, Atarod M, Hekmat S, Rashighi M, Solhpour A. Comparison of hydration, sebum and pH values in clinically normal skin of patients with atopic dermatitis and healthy controls. Clinical & Experimental Dermatology. 2007 May; 32(3): 321-322.

Firooz A, Nasiri M, Sarhangnejad R, Rashighi M, Gorouhi F. Frequency of false positive responses in patients with multiple positive reactions in patch test. Iranian Journal of Dermatology. 2007 Jan; 10(1): 26-31.

Ghasemi A, Gorouhi F, Rashighi M, Jafarian S, Firooz A. Striae gravidarum: associated factors. Journal of European Academy of Dermatology and Venereology. 2007 Jul; 21(6): 743-746.

Rashighi M, Firooz A, Gorouhi F, Dowlati Y. Iran's contribution to the dermatology literature. International Journal of Dermatolgy. 2007 Jun; 46(6): 650-660.

Firooz A, Khamesipour A, Ghoorchi MH, Nassiri-Kashani M, Eskandari SE, Khatami A, Hooshmand B, Gorouhi F, Rashighi M, Dowlati Y. Imiquimod in combination with meglumine antimoniate for acute cutaneous leishmaniasis: A randomized assessor-blind controlled trial. Archives of Dermatology. 2006 Dec; 142(12): 1575-1579.

Firooz A, Solhpour AR, Gorouhi F, Daneshpazhooh M, Balighi K, Farsinejad K, Rashighi M, Dowlati Y. Pimecrolimus cream 1% vs. hydrocortisone acetate cream 1% in the treatment of facial seborrheic dermatitis: A randomized, investigator blind, clinical trial. Archives of Dermatology. 2006 Aug; 142(8): 1066-1067.

Firooz A, Rashighi M, Ghazisaidi B, Dowlati Y. (2005, January 12). Concepts of patients with alopecia areata about their disease. www.biomedcentral.com/1471-5945/5/1

Firooz A, Bouzari N, Fallah N, Ghazisaidi B, Rashighi M, Dowlati Y. What patients with vitiligo believe about their condition. International Journal of Dermatology. 2004 Nov; 43(11): 811-814.

Firooz A, Rashighi M, Dowlati Y. Rosacea fulminans (pyoderma faciale): successful treatment of a 3-year-old girl with oral isotretinoin. International Journal of Dermatolgy. 2001 Mar; 40(3): 203-205.

Firooz AR, Rashighi M, Ghazi Saidi B, Dowlati Y. Illness perception and quality of life in patients with Alopecia Areata. Iranian Journal of Dermatology. 2001 Apr; 40(15): 11-17.

Book Chapters & Guidelines
Harris JE and Rashighi M. Vitiligo. In: Mark G. Lebwohl, Warren R. Heymann, John Berth-Jones, and Ian Coulson. Treatment of Skin Disease. Saunders; 5th edition; 2017.

Rashighi M and Harris JE. Vogt-Koyanagi-Harada Syndrome, in Clinical Decision Support: Dermatology. (2015-current). Decision Support in Medicine, LLC.

Rashighi M and Harris JE. Vitiligo topic, in British Medical Journal: Best Practice. (2014-current). BMJ Publishing Group Limited

Rashighi M and Burgin S. Alezzandrini syndrome. VisualDx. (2017-current).

Rashighi M and Burgin S. Hypomelanosis of Ito. VisualDx. (2017-current).

Rashighi M, Tan B, Burgin S. Incontinentia pigmenti. VisualDx. (2017-current).

Rashighi M and Burgin S. Nevus depigmentosus. VisualDx. (2017-current).

Rashighi M and Burgin S. Piebaldism. VisualDx. (2017-current).

Rashighi M, Wong V, Burgin S. Segmental vitiligo. VisualDx. (2017-current).

Rashighi M and Burgin S. Vogt-Koyanagi-Harada syndrome. VisualDx. (2017-current).

Rashighi M and Burgin S. Waardenburg syndrome. VisualDx. (2017-current).

Rashighi M, Tan B, Burgin S. Discoid lupus erythematosus in adults. VisualDx. (2018 current).

Rashighi M, Tan B, Burgin S, Burkhart C, Morrell D. Discoid lupus erythematosus in child. VisualDx. (2018-current).

Rashighi M, Tan B, Burgin S. Subacute cutaneous lupus erythematosus in adults. VisualDx. (2018-current).

Rashighi M, Tan B, Burgin S. Tumid lupus erythematosus in adults. VisualDx. (2018-current).

Meetings Invited Speaker

“Understanding autoimmunity through translational research in inflammatory skin diseases.” Ground round at the HSS Research Institute. New York, NY, 2019.

“Translational research in cutaneous lupus.” Annual Meeting of the Childhood Arthritis and Rheumatology Research Alliance. Louisville, KY, 2019.

“Vitiligo: Immunopathogenesis and emerging treatments.” Spring Continental Congress of Dermatology. Tehran, Iran, 2018.

“IFN-g-induced chemokines are required for depigmentation in a mouse model of vitiligo.” 75th Annual Meeting of the Society for Investigative Dermatology; Raleigh, NC, 2012.

“CXCL10, an IFN-g-induced chemokine, is required for the development of depigmentation in a mouse model of vitiligo.” Vitiligo Working Group, VR Foundation; San Diego, CA, 2012.

“Iran's Contribution to Dermatology Literature.” Symposium of Current

Issues and Challenges in Public Health jointly organized by the U.S. National Institutes of Health (NIH), the Aspen Health, Biomedical Science and Society Initiative and Aspen Institute; Washington, DC, 2006.

Additional Resources
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