Featured Publications
Das D, Dey S, Brewster RC*, Chuobey S.* (2017). Effect of Transcription Factor Resource Sharing on Gene Expression noise, PLoS Comp Bio 13, e1005491.
Tavares-Cadete F, Norouzi D, Dekker B, Liu Y, Dekker J. (2020) Multi-contact 3C reveals that the human genome during interphase is largely not entangled. Nat Struct Mol Biol On line.
Abramo K, Valton A-L, Venev SV, Ozadam H, Fox AN, Dekker J. (2019). A Chromosome Folding Intermediate at the Condensin-to-Cohesin Transition During Telophase. Nat Cell Biol 21, 1393-1402.
Schwartz HR*, Richards R*, Fontana RE, Joyce AJ, Honeywell ME, Lee MJ. (2020). Drug GRADE: an Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response Profiles. Cell Rep 31, 107800.
Richards R, Schwartz HR, Honeywell ME, Stewart MS, Cruz-Gordillo P, Joyce AJ, Landry BD, Lee MJ. (2020) Drug Antagonism and Single Agent Dominance Result from Differences in Death Kinetics. Nature Chem Biol 16, 791-800.
Xavier JB, et al. (2019). The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View. Trends in Cancer.
Dahan O, Dorfman BS, Sayin S, Rosener B, Hua T, Yarden A, Mitchell A. (2019). Harnessing robotic automation and web-based technologies to modernize scientific outreach. PLoS Biology.
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Grubbs KJ*, Bleich RM*, Santa Maria KC, Allen SE, AgBiome Team, Shank EA, and Bowers AA. (2017) Large-scale bioinformatics analysis of Bacillus genomes uncovers conserved roles of natural products in bacterial physiology. mSystems 2, pii:e00040-17.
Rosener B, Sayin S, Oluoch PO, Garcia Gonzalez AP, Mori H, Walhout AJM, Mitchell A. (2020). Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host. eLife 2020;9:e59831.Yilmaz LS, Li X, Nanda S, Fox B, Schroeder F, Walhout AJM. (2020). Modeling tissue‐relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels. Mol Syst Biol 16:e9649.
Maire T, Allertz T, Betjes MA, Youk H. (2020) Dormancy-to-death transition in yeast spores occurs due to gradual loss of gene-expressing ability, Mol Syst Biol Mol Syst Biol 16:e9245.
Laman Trip DS, Youk H. (2020) Yeasts collectively extend the limits of habitable temperatures by secreting glutathione, Nature Microbiology 5:943-954.