Knowledge to cure
Our research is focused on identifying and characterizing new mechanisms of RNA regulation in the dynamic control of gene expression. We apply this knowledge to explore how RNA regulatory pathways impact stem cell pluripotency, mammalian development, growth, cancer, and neurological diseases. Ultimately we aim to exploit this understanding for the development of new therapeutic approaches for cancer and degenerative disease.
Research Overview
We aim to discover novel mechanisms and pathways of RNA regulation with the goal of developing new therapies for cancer and other diseases.
Current Research
Ongoing research projects in the lab seek to understand how RNA regulation, modification, and metabolism play a role in development and disease.
Discoveries
We have made significant contributions to the areas of miRNA biogenesis and function, RNA metabolism, and RNA methylation and epitranscriptomics.