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Vincent M. Rotello, PhD

Research Focus - Nanomaterials for Cancer Diagnostics and Therapeutics

  • Use of high-content high-throughput phenotyping of cells for determining cancer chemotherapeutic mechanisms and screening cancer stem cell therapeutics
  • Application of bioorthogonal approaches to cancer therapy, including catalytic nanoparticles (nanozymes)
  • Delivery of proteins and nucleic acids (siRNA, mRNA) for cancer therapy
  • CRISPR gene editing of macrophages for cancer immunotherapy

Representative Publication

Geng Y, Goel HL, Le NB, et al. Rapid phenotyping of cancer stem cells using multichannel nanosensor arrays. Nanomedicine. 2018;14(6):1931-1939.

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