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Cancer Nexus Blog

Read up on the Center's latest developments in cancer research, screening and prevention, as well as innovations in cancer detection and treatment.

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    Bringing Drugs to the Brain Takes Ingenuity: A Conversation with Rachael Sirianni, PhD

    Rachael Sirianni, PhD, is working on ways to deliver drugs directly to the brain. Her research has broad implications for treating brain cancer and neurodegenerative disorders.

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    Reviving the Immune Response in Pancreatic Cancer

    Marcus Ruscetti, PhD, and Loretah Chibaya, PhD, explain how they successfully activated the immune system in a pancreatic cancer model.

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    Next Generation Science Meets Next Generation Scientists: Neuroblastoma, Nanoparticles and Immunotherapy

    This summer, Prabhani Atukorale, PhD, and Jason Shohet, MD, PhD, will work with a visiting student, on developing an immunotherapy for neuroblastoma.

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    An Inside Look at Pancreatic Tumor Cells: A Conversation with Jason Pitarresi, PhD

    Jason Pitarresi, PhD, tells us about his research path and the tools he is using to better understand pancreatic cancer.

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    Fighting Back Against Gastrointestinal Stromal Tumors

    Matthew Hemming, MD, PhD, is developing new therapies for gastrointestinal stromal tumors and other sarcomas. He is also identifying new biomarkers for assessing risk of tumor recurrence.

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    How Mitochondria Survive in Cancer Cells: A Conversation with Jessica Spinelli, PhD

    Jessica Spinelli, PhD, explains how tumor cells can survive without oxygen

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    Pushing Back on Glioblastoma

    Samantha Sarli and Jonathan Watts, PhD are working on a novel drug to treat glioblastoma.

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    Accolades Once Again for the Cancer Research Office

    The Cancer Research Office is commended for their outstanding performance — once again!

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    Stopping Blood Cancer Before It Starts

    Shyam Patel, MD, PhD, explains a new method for detecting blood cancer before it takes root.

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    It’s All about the Gaps: Why Chemotherapy Works on Some Cells but Not Others

    Sharon Cantor, PhD, explains why chemotherapy for hereditary breast and ovarian cancer doesn't always work as expected.

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    A Translational Approach to T cells: A Conversation with Jillian Richmond, PhD

    Jillian Richmond, PhD, discusses her T cell research and its application to diagnostics and therapies for lymphoma.

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    UMass Chan is attending major cancer conference to share advances in cancer research

    Follow Our Research Presentations at the AACR Annual Meeting 2022

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    Simulated Emergencies to the Rescue

    UMass thoracic surgeons perform simulated surgery using a robotic platform to train for an emergency conversion to an open procedure.

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    Paving the Path for Neuro-Oncology Translational Research: A Conversation with David Cachia, MD

    David Cachia, MD talks about future neuro-oncology clinical trials at UMass Chan

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    Adapt2YourMood: A Mood-tailored Intervention for Smoking Cessation

    A pilot study to develop new bioinformatic tools to identify fusion circRNAs in cancer has received funding from the UMass Cancer Center and PQHS

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    Using Single-Cell Profiling to Uncover Vulnerabilities in Breast Cancer

    A study on the epigenetic vulnerabilities of metastatic breast cancer has received funding from the UMass Cancer Center

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    A Dual Approach to Activate the Immune System in Pancreatic Cancer

    A pilot study to develop a unique approach to enhance immunotherapy for pancreatic cancer has received funding from the UMass Cancer Center

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    AIMing to Improve the Response of Melanoma to Immunotherapy

    An early-stage research study of immunotherapy in melanoma has received funding from the UMass Cancer Center

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    Developing Computational Methods to Detect Fusion Circular RNAs in Cancer

    UMass Cancer Center and PQHS fund a pilot study to develop new bioinformatic tools to identify fusion circRNAs in cancer

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    UMass CRO Receives Recognition for Outstanding Performance

    The UMass Cancer Research Office has received national recognition from ECOG-ACRIN for outstanding performance in clinical trials research

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    New Research Sheds Light on Treatment for TP53-Mutant Blood Cancers

    Dr. Patel discusses his new research defining the clinico-genomic landscape of TP53 mutations in patients with AML

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    Using Comparative Genomics to Fight Cancer in Dogs and Humans

    By studying cancer in dogs, researchers at UMass Cancer Center are working to improve the outcomes and extend the lives of both human patients and pet dogs with cancer

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    UMass Selected as Clinical Trial Site for New Experimental Cancer Drug

    UMass was selected as one of only a few sites around North America offering a phase I/II clinical trial involving intratumoral injection

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    Leveraging mHealth to Increase Physical Activity in Cancer Survivors

    Aiming to provide direct link between providers and physical activity programs to conduct patient referrals

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    Combating drug resistance in melanoma

    Ceol 's lab have developed a drug that targets this factor and is currently testing whether it can combat drug resistance when used in combination with current therapies.

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