Michael Brehm, PhD
Research Focus - Regulation of Human T Cell Function and Homeostasis
- Characterization of interactions between human T cells and tumors
- Control of human T cell function within the tumor micro-environment by checkpoint blockade
- Establishment of human avatar models to study immuno-oncology
- Elucidation of cytokine control of human T cell responses
Representative Publication
Jangalwe S, Kapoor VN, Xu J, Girnius X, Kennedy NJ, Edwards YJK, Welsh RM, Davis RJ, Brehm MA(2019) Cutting Edge: Early attrition of memory T cells during inflammation and costimulation blockade is regulated concurrently by proapoptotic proteins Fas and Bim. J Immunol. 202(3):647-651.