Site Menu
Buscar Close Search
Buscar Close Search
Page Menu

A.J. Marian Walhout, PhD

Research Focus - Worms and Bugs: A Model for Cancer and Chemotherapeutic Drug Response

  • Use of C. elegans and its bacterial diet as a model for dietary effects on cancer-related metabolism
  • Characterization of the effects of the microbiome on chemotherapeutic drug response
  • Study of the influence of gut microbiota on chemotherapeutic drug side effects
  • Identification of factors and pathways targeted by the oncometabolite 2-hydroxyglutarate

Representative Publication

García-González AP, Ritter AD, Shrestha S, et al. Bacterial metabolism affects the C. elegans response to cancer chemotherapeutics Cell. 2017;169(3):431-441.

Read Publication

More Publications

In the News

Getting Results…
  • Chancellor Collins: Momentum high at UMass Chan after year of milestone accomplishments
    Community News

    Chancellor Collins: Momentum high at UMass Chan after year of milestone accomplishments

    In his annual Convocation address to the UMass Chan Medical School community on Thursday, Sept. 16, Chancellor Michael F. Collins expressed optimism for the Medical School’s ambitious future and touted the enormous momentum moving the school forward.

    Read more
  • Heat shot of Albertha J.M. "Marian" Walhout taken at UMass Chan Medical School in 2021.
    Research News

    Collaborative effort led by Marian Walhout spotlights worms as model for personalized medicine

    UMass Chan researcher Marian Walhout, PhD, along with collaborators at Northwestern and Cornell, have developed an animal model system to interrogate individual differences in metabolism.

    Read more
  • Heat shot of Albertha J.M. "Marian" Walhout taken at UMass Chan Medical School in 2021.
    Research News

    UMass Chan Medical School establishes new Department of Systems Biology

    The Program in Systems Biology has been elevated to full department status, with Marian Walhout, PhD, serving as the founding chair of the Department of Systems Biology.

    Read more