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Kate Fitzgerald, PhD

Research Focus - Leveraging Nucleic Acid Sensing Pathways for Cancer Immunotherapy

  • Understanding inflammatory responses and colonic cancer
  • Elucidating tumor DNA-driven responses
  • Characterizing the cGAS (cyclic GMP-AMP synthase)-STING (stimulator of interferon genes) signaling pathway and anti-tumor immunity 

Representative Publication

Motwani M, Pesiridis S, Fitzgerald KA. DNA sensing by the cGAS-STING pathway in health and disease. Nat Rev Genet. 2019;20(11):657-674.

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  • Katherine Fitzgerald, Phillip Zamore elected to American Academy of Arts & Sciences

    Katherine Fitzgerald, Phillip Zamore elected to American Academy of Arts & Sciences

    Katherine Fitzgerald, PhD, and Phillip D. Zamore, PhD, were elected to the American Academy of Arts & Sciences, which honors excellence and leaders from every field of human endeavor to examine new ideas, address issues of importance to the nation and the world, and work together to cultivate every art and science.

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  • UMass Chan scientists deliver siRNA therapy to lung

    UMass Chan scientists deliver siRNA therapy to lung

    A multidisciplinary team of UMass Chan scientists has developed a technology for delivering siRNA molecules locally to lung tissue, providing the first evidence of a platform capable of delivering chemically modified siRNAs to the lungs nasally and achieving robust genetic silencing.

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  • Nanobody treatment developed by MassBiologics shows promise for treating SARS-CoV-2 infection

    Nanobody treatment developed by MassBiologics shows promise for treating SARS-CoV-2 infection

    MassBiologics of UMass Chan Medical School develops novel nanobody as inhalable and affordable medicine against SARS-CoV-2 and emerging variants.

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  • UMass Chan BRIDGE Fund supports seven faculty projects with commercialization potential

    UMass Chan BRIDGE Fund supports seven faculty projects with commercialization potential

    BRIDGE Innovation and Business Development at UMass Chan Medical School has awarded $2.2 million to seven faculty-led biomedical research projects.

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  • Innate Immunity Day at UMass Chan will honor Robert Finberg

    Innate Immunity Day at UMass Chan will honor Robert Finberg

    The Program in Innate Immunity will host the annual Innate Immunity Day scientific symposium in honor of Robert W. Finberg, MD, at UMass Chan Medical School on Wednesday, May 25. Registration opens April 1.

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  • UMass Center for Clinical and Translational Science awards seven new pilot grants

    UMass Center for Clinical and Translational Science awards seven new pilot grants

    The UMass Center for Clinical and Translational Science has awarded seven pilot grants faculty and research collaborators to accelerate the translation for basic discoveries into practical, cost-effective solutions that improve human health.

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  • Katherine Fitzgerald to receive American Association of Immunologists award

    Katherine Fitzgerald to receive American Association of Immunologists award

    Katherine A. Fitzgerald, PhD, has been named the 2022 recipient of the American Association of Immunologists - Thermo Fisher Meritorious Career Award.

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  • Four interdisciplinary collaborations share mission to demystify devastating brain disorders

    Four interdisciplinary collaborations share mission to demystify devastating brain disorders

    The Dan and Diane Riccio Fund for Neuroscience has awarded four teams of UMass Medical School researchers $50,000 seed grants for interdisciplinary collaborations leading to innovative discoveries that deepen understanding of normal brain function and what goes awry in neurological diseases.

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  • UMass Chan research identifies potential antiviral compound for COVID-19, flu, other viral infection

    UMMS research identifies potential antiviral compound for COVID-19, flu, other viral infection

    Katherine A. Fitzgerald, PhD; Fiachra Humphries, PhD; and Liraz Galia, PhD, working with the British-based pharmaceutical company GlaxoSmithKline, have identified a novel molecule capable of stimulating the innate immune system against SARS-CoV-2 virus.

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  • Katherine Fitzgerald and Nikolaus Grigorieff elected to National Academy of Sciences

    Katherine Fitzgerald and Nikolaus Grigorieff elected to National Academy of Sciences

    Two UMass Medical School professors have been elected to the National Academy of Sciences in recognition of their distinguished and continuing achievements in original research.

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  • UMass Chan immunologist Katherine Fitzgerald admitted to Royal Irish Academy

    UMMS immunologist Katherine Fitzgerald admitted to Royal Irish Academy

    UMass Medical School researcher and world-renowned immunologist Katherine A. Fitzgerald, PhD, has been named an honorary member of the Royal Irish Academy.

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  • Katherine Fitzgerald and Sanjay Ram elected to American Academy of Microbiology

    Katherine Fitzgerald and Sanjay Ram elected to American Academy of Microbiology

    Katherine Fitzgerald, PhD, and Sanjay Ram, MD, were elected to the American Academy of Microbiology. Fellows are elected annually through a highly selective, peer-review process, based on their records of scientific achievement and original contributions that have advanced microbiology.

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