Jessica Spinelli, PhD
Research Focus - Metabolic Flexibility in the Tumor Microenvironment
- Hypoxia and metabolic adaptations in the tumor microenvironment
- Flexibility of ETC circuits in cancer
- The mechanisms underlying ETC complex mutations that drive tumor growth
- Novel mitochondrial functions in tumors
Representative Publication
Spinelli JB, Rosen PC, Sprenger HG, et al. Fumarate is a terminal electron acceptor in the mammalian electron transport chain. Science. 2021; 374(6572):1227-1237.